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TÜBİTAK

Turkish Journal of Medical Sciences

2002

Alloxane diabetes

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Full-Text Articles in Medicine and Health Sciences

The Problem Of Lipid Exchange In Vessel Walls In Insulin Deficit, Gulchekhra M. Irgasheva, Lyudmila Sergeevna Klemesheva, Karim Tadjibaevich Almatov Jan 2002

The Problem Of Lipid Exchange In Vessel Walls In Insulin Deficit, Gulchekhra M. Irgasheva, Lyudmila Sergeevna Klemesheva, Karim Tadjibaevich Almatov

Turkish Journal of Medical Sciences

It has been revealed that in alloxane diabetes the content of the main phospholipids - phosphatidylcholine, phosphatidyletanolamine and phosphatidyl-phosphatidylinosite -decreases in the cells of the vascular wall, whereas the content of the methyl ethers of the fatty acids is not changed, and the content of the fractions of lipids (monoglycerides, diglycerides, triglycerides, cholesterol, free fatty acids, and cholesterol ethers) and phospholipids (phosphatidylserine, cardiolipin, lysophosphatidyletanolamine, lysocardiolipin, sphingomyelin, phosphatide acid and lysophosphatide acid) increase. The depth of these changes correlates with the heaviness of the pathological process.