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Full-Text Articles in Medicine and Health Sciences
Animal Models And Therapeutic Molecular Targets Of Cancer: Utility And Limitations., Maria Cekanova Ms, Rndr, Phd, Kusum Rathore
Animal Models And Therapeutic Molecular Targets Of Cancer: Utility And Limitations., Maria Cekanova Ms, Rndr, Phd, Kusum Rathore
Maria Cekanova MS, RNDr, PhD
Cancer is the term used to describe over 100 diseases that share several common hallmarks. Despite prevention, early detection, and novel therapies, cancer is still the second leading cause of death in the USA. Successful bench-to-bedside translation of basic scientific findings about cancer into therapeutic interventions for patients depends on the selection of appropriate animal experimental models. Cancer research uses animal and human cancer cell lines in vitro to study biochemical pathways in these cancer cells. In this review, we summarize the important animal models of cancer with focus on their advantages and limitations. Mouse cancer models are well known, …
Mycobacterium Ulcerans Fails To Infect Through Skin Abrasions In A Guinea Pig Infection Model: Implications For Transmission, H R. Williamson, L Mosi, Robert L. Donnell, M Aqqad, R W. Merritt, P L. Small
Mycobacterium Ulcerans Fails To Infect Through Skin Abrasions In A Guinea Pig Infection Model: Implications For Transmission, H R. Williamson, L Mosi, Robert L. Donnell, M Aqqad, R W. Merritt, P L. Small
Robert L Donnell DVM, Ph.D., DACVP College of Veterinary Medicine
Transmission of M. ulcerans, the etiological agent of Buruli ulcer, from the environment to humans remains an enigma despite decades of research. Major transmission hypotheses propose 1) that M. ulcerans is acquired through an insect bite or 2) that bacteria enter an existing wound through exposure to a contaminated environment. In studies reported here, a guinea pig infection model was developed to determine whether Buruli ulcer could be produced through passive inoculation of M. ulcerans onto a superficial abrasion. The choice of an abrasion model was based on the fact that most bacterial pathogens infecting the skin are able to …
Magnetic Resonance Imaging (Mri) Spinal Cord And Canal Measurements In Normal Dogs, Silke Hecht, M M. Huerta, Robert B. Reed
Magnetic Resonance Imaging (Mri) Spinal Cord And Canal Measurements In Normal Dogs, Silke Hecht, M M. Huerta, Robert B. Reed
Silke Hecht
The goal of this study was to establish Magnetic resonance imaging (MRI) reference ranges for spinal measurements in normal dogs. Forty dogs (1–10 kg, 11–20 kg, 21–30 kg, > 30 kg; 10 dogs per category) underwent spinal MRI. Measurements were performed on sagittal T2-W images at the level of the 4th thoracic vertebra (T4), the 9th thoracic vertebra (T9) and the 3rd lumbar vertebra (L3). Spinal canal diameter (mm) ranged from 6.07 ± 0.63 (1–10 kg) to 8.27 ± 1.15 (> 30 kg) at the level of T4; 6.55 ± 0.61 (1–10 kg) to 9.04 ± 1.26 (> 30 kg) at …
From The Outside Looking In: A Response To The Hijacking Of Recreational Therapy, Daniel L. Dustin, Kelly S. Bricker, Keri A. Schwab
From The Outside Looking In: A Response To The Hijacking Of Recreational Therapy, Daniel L. Dustin, Kelly S. Bricker, Keri A. Schwab
Keri Schwab
Where does Dr. Austin want his line of thought to lead and what does he expect from the larger field of parks and recreation in return? Is he after reassurance that recreational therapy is valued by the rest of us? Does he want recreation therapists to be acknowledged as the closest thing we have in our midst to medical doctors? Or does he want recreational therapy to disassociate itself from the field of parks and recreation altogether? If recreation therapists want to be viewed as distinct and different from the rest of us, if it is autonomy they are after, …
His Name Is Alton, Susan Sanders
Making Better Decisions During Triage, Susan Sanders, Ptlene Minick
Making Better Decisions During Triage, Susan Sanders, Ptlene Minick
Susan F Sanders PhD, RN
No abstract provided.