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Full-Text Articles in Medicine and Health Sciences

Tenascin-C In Betel-Quid Associated Lesions, Rosnah Binti Zain, Fukano H., Ikeda N., Kudeken W., Shrestha P., Ghazali M. N., Takai Y., Mori M. Apr 1999

Tenascin-C In Betel-Quid Associated Lesions, Rosnah Binti Zain, Fukano H., Ikeda N., Kudeken W., Shrestha P., Ghazali M. N., Takai Y., Mori M.

Prof. Dr. Rosnah Binti Zain

The expression of Tenascin-C, an adhesion modulating or anti- adhesive extracellular matrix protein, was evaluated in betel quid associated lesions of oral mucosa showing focal hyperkeratosis (n=15), dysplasia (n=15), oral submucous fibrosis (n=7) and oral squamous cell carcinoma (n=8). All the patients were chewers of betel quid containing betel leaves, areca nuts, lime and tobacco. The results obtained from this study were compared to similar lesions in smokers and non-quid users cited in the literature (Shrestha et al, Oral Oncol, 1994). An enhanced expression of TN-C was observed in epithelial connective tissue interface of quid associated hyperkeratotic and dyplastic mucosa. …


Median Mental Sinus In Twins, W.C. Ngeow, S. T. Ong Apr 1999

Median Mental Sinus In Twins, W.C. Ngeow, S. T. Ong

Wei Cheong Ngeow

Sinus on the chin can be the result of a chronic apical abscess due to pulp necrosis of a mandibular anterior tooth. The tooth is usually asymptomatic, and a dental cause is therefore not apparent to the patient or the unsuspecting clinician. Not infrequently, the patient may seek treatment from a dermatologist or general surgeon instead of a dentist. Excision and repair of the fistula may be carried out with subsequent breakdown because the dental pathology is not removed. This paper reports the presence of median mental sinus of dental origin in twins. One case healed following root canal therapy …


Pcna Expression In Epithelial Linings Of Odontogenic Cysts And Unicystic Ameloblastoma, Sudiono J., Rosnah Binti Zain Apr 1999

Pcna Expression In Epithelial Linings Of Odontogenic Cysts And Unicystic Ameloblastoma, Sudiono J., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

Proliferating cell nuclear antigen (PCNA) is a nuclear protein synthesized in the late G1 and S phase of the cell cycle. It is a useful marker for the proliferating fraction of cells in tissue specimens. The purpose of this study was to describe the expression of PCNA within epithelial linings of odontogenic cyst and to compare the proliferative activities of these lesion using PCNA labeling indices. A total of 61 cases of odontogenic cysts and unicystic ameloblastomas (18 radicular cysts, 16 dentigerous cysts, 15 odontogenic keratocysts (OKC) an 12 unicystic ameloblastomas) was studied. It was found that PCNA staining were …


Oral Mucosal Lesions Associated With Betel Quid, Areca Nut And Tobacco Chewing Habits: Consensus From A Workshop Held In Kuala Lumpur, Malaysia, November 25-27, 1996, Rosnah Binti Zain, Ikeda N., Gupta P. C., Warnakulasuriya S., Van Wyk C. W., Shrestha P., Axéll T. Dec 1998

Oral Mucosal Lesions Associated With Betel Quid, Areca Nut And Tobacco Chewing Habits: Consensus From A Workshop Held In Kuala Lumpur, Malaysia, November 25-27, 1996, Rosnah Binti Zain, Ikeda N., Gupta P. C., Warnakulasuriya S., Van Wyk C. W., Shrestha P., Axéll T.

Prof. Dr. Rosnah Binti Zain

A variety of betel/areca nut/tobacco habits have been reviewed and categorized because of their possible causal association with oral cancer and various oral precancerous lesions and conditions, and on account of their widespread occurrence in different parts of the world. At a recent workshop in Kuala Lumpur it was recommended that 'quid' be defined as 'a substance, or mixture of substances, placed in the mouth or chewed and remaining in contact with the mucosa, usually containing one or both of the two basic ingredients, tobacco and/or areca nut, in raw or any manufactured or processed form.' Clear delineations on contents …