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Articles 1 - 19 of 19
Full-Text Articles in Medicine and Health Sciences
Association Of Dc-Sign Promoter Polymorphism With Increased Risk For Parenteral, But Not Mucosal, Acquisition Of Human Immunodeficiency Virus Type 1 Infection, Maureen P. Martin, Michael M. Lederman, Holli B. Hutcheson, James J. Goedert, George W. Nelson, Yvette Van Kooyk, Roger Detels, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington
Association Of Dc-Sign Promoter Polymorphism With Increased Risk For Parenteral, But Not Mucosal, Acquisition Of Human Immunodeficiency Virus Type 1 Infection, Maureen P. Martin, Michael M. Lederman, Holli B. Hutcheson, James J. Goedert, George W. Nelson, Yvette Van Kooyk, Roger Detels, Susan Buchbinder, Keith Hoots, David Vlahov, Stephen J. O'Brien, Mary Carrington
Biology Faculty Articles
There is considerable debate about the fundamental mechanisms that underlie and restrict acquisition of human immunodeficiency virus type 1 (HIV-1) infection. In light of recent studies demonstrating the ability of C type lectins to facilitate infection with HIV-1, we explored the potential relationship between polymorphisms in the DC-SIGN promoter and risk for acquisition of HIV-1 according to route of infection. Using samples obtained from 1,611 European-American participants at risk for parenteral (n = 713) or mucosal (n = 898) infection, we identified single-nucleotide polymorphisms in the DC-SIGN promoter using single-strand conformation polymorphism. Individuals at risk for parenterally acquired …
Angiotensin Ii Type 2 Receptor Gene Transfer Elicits Cardioprotective Effects In An Angiotensin Ii Infusion Rat Model Of Hypertension, Beverly L. Falcón, Jillian M. Stewart, Erick Bourassa, Michael J. Katovich, Glenn Walter, Robert C. Speth, Colin Sumners, Mohan K. Raizada
Angiotensin Ii Type 2 Receptor Gene Transfer Elicits Cardioprotective Effects In An Angiotensin Ii Infusion Rat Model Of Hypertension, Beverly L. Falcón, Jillian M. Stewart, Erick Bourassa, Michael J. Katovich, Glenn Walter, Robert C. Speth, Colin Sumners, Mohan K. Raizada
HPD Articles
The role of the angiotensin II type 2 receptor (AT2R) in cardiovascular physiology remains elusive. We have developed an in vivo lentiviral vector-mediated gene transfer system to study the physiological functions of the AT2R. Our objectives in this study were to determine whether the AT2R influences cardiac hypertrophy and myocardial and perivascular fibrosis in a nongenetic rat model of hypertension. Lentiviral vector containing the AT2R or saline was injected intracardially in 5-day-old Sprague-Dawley rats. This resulted in a persistent overexpression of the AT2R in cardiac tissues. At 15 wk of age, animals were infused with either 200 ng x kg(-1) …
Apobec3g Genetic Variants And Their Influence On The Progression To Aids, Ping An, Gabriela Bleiber, Priya Duggal, George Nelson, Margaret May, Bastien Mangeat, Irene Alobwede, Didier Trono, David Vlahov, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Stephen J. O'Brien, Amalio Telenti, Cheryl Winkler
Apobec3g Genetic Variants And Their Influence On The Progression To Aids, Ping An, Gabriela Bleiber, Priya Duggal, George Nelson, Margaret May, Bastien Mangeat, Irene Alobwede, Didier Trono, David Vlahov, Sharyne Donfield, James J. Goedert, John Phair, Susan Buchbinder, Stephen J. O'Brien, Amalio Telenti, Cheryl Winkler
Biology Faculty Articles
The cytosine deaminase APOBEC3G, in the absence of the human immunodeficiency virus type 1 (HIV-1) accessory gene HIV-1 viral infectivity factor (vif), inhibits viral replication by introducing G→A hypermutation in the newly synthesized HIV-1 DNA negative strand. We tested the hypothesis that genetic variants of APOBEC3G may modify HIV-1 transmission and disease progression. Single nucleotide polymorphisms were identified in the promoter region (three), introns (two), and exons (two). Genotypes were determined for 3,073 study participants enrolled in six HIV-AIDS prospective cohorts. One codon-changing variant, H186R in exon 4, was polymorphic in African Americans (AA) (f < 37%) and rare in European Americans (f < 3%) or Europeans (f …
College Of Dental Medicine Student Handbook June 2004, Nova Southeastern University
College Of Dental Medicine Student Handbook June 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Optometry Student Handbook June 2004, Nova Southeastern University
College Of Optometry Student Handbook June 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Genomically Intact Endogenous Feline Leukemia Viruses Of Recent Origin, Alfred L. Roca, Jill Pecon-Slattery, Stephen J. O'Brien
Genomically Intact Endogenous Feline Leukemia Viruses Of Recent Origin, Alfred L. Roca, Jill Pecon-Slattery, Stephen J. O'Brien
Biology Faculty Articles
We isolated and sequenced two complete endogenous feline leukemia viruses (enFeLVs), designated enFeLV-AGTT and enFeLV-GGAG. In enFeLV-AGTT, the open reading frames are reminiscent of a functioning FeLV genome, and the 5′ and 3′ long terminal repeat sequences are identical. Neither endogenous provirus is genetically fixed in cats but polymorphic, with 8.9 and 15.2% prevalence for enFeLV-AGTT and enFeLV-GGAG, respectively, among a survey of domestic cats. Neither provirus was found in the genomes of related species of the Felis genus, previously shown to harbor enFeLVs. The absence of mutational divergence, polymorphic incidence in cats, and absence in related species suggest that …
Physician Assistant 2004, Nova Southeastern University
Physician Assistant 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Doctor Of Health Science Overview, Nova Southeastern University
Doctor Of Health Science Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Pharmacy Entry Level Program Overview, Nova Southeastern University
College Of Pharmacy Entry Level Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Bachelor Of Health Science, Nova Southeastern University
Bachelor Of Health Science, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Medical Sciences Master Of Biomedial Sciences (Mbs) 2004, Nova Southeastern University
College Of Medical Sciences Master Of Biomedial Sciences (Mbs) 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Optometry Program Overview, Nova Southeastern University
College Of Optometry Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Health Professions Division Catalog 2004-2005, Nova Southeastern University
Health Professions Division Catalog 2004-2005, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Pharmacy Student Handbook June 2004, Nova Southeastern University
College Of Pharmacy Student Handbook June 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Occupational Therapy Program 2004, Nova Southeastern University
Occupational Therapy Program 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Physical Therapy 2004, Nova Southeastern University
Physical Therapy 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Master Of Science In Public Health Program Overview, Nova Southeastern University
Master Of Science In Public Health Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Adiology 2004, Nova Southeastern University
Adiology 2004, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Osteopathic Medicine Program Overview, Nova Southeastern University
College Of Osteopathic Medicine Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.