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Full-Text Articles in Medicine and Health Sciences

The Effects Of Stress On American Football Overhand Throw Accuracy, Cale Anderson Dec 2018

The Effects Of Stress On American Football Overhand Throw Accuracy, Cale Anderson

All NMU Master's Theses

The American overhand football throw is a highly scrutinized position because of all the different kinds of stress both physical and psychological that are put onto those players. The current study sought to develop a formula using psycho-emotional and physical variables to predict the performance of an American overhand football throw under stressful/non-stress situations. Participants were tested on two days. The stress situation is where tennis balls were thrown, and the subject did not know where they were going to throw. The non-stressed was a 3 step drop without knowing what target they were throwing at and these conditions were …


Biomechanical Adaptations To An Implemented Ramp Angle In Recreational Alpine Skiers, Stephanie R. Moore Dec 2018

Biomechanical Adaptations To An Implemented Ramp Angle In Recreational Alpine Skiers, Stephanie R. Moore

All NMU Master's Theses

Most ski boot-binding complexes have a negative ramp angle. This angle is not regulated or reported in the alpine ski industry, but may influence skier balance and pressure control. Thus, joint coordination and center of pressure maintenance in alpine skiers (n = 19) was investigated during simulated ski squat and balance tasks with increasing binding ramp angles (0°, 1°, 2°). Greater sagittal plane center of pressure excursions were observed with ski-booted tasks compared to barefoot conditions during squats and balance simulations. Squat tasks performed on skis resulted in more uncoordinated knee-ankle movement, however, this effect was reduced with the highest …


Characterization Of Theranostic Peptides For Glioblastoma Multiforme, Aaron Mellesmoen Aug 2018

Characterization Of Theranostic Peptides For Glioblastoma Multiforme, Aaron Mellesmoen

All NMU Master's Theses

Glioblastoma multiforme (GBM) is a type of primary CNS tumor in which viable treatment options do not exist. Standard of care including tumor resection, chemotherapy, and radiation does little to extend the 5-year survival expectancy past 5.1%. Herein, two small-peptide molecules with inherent antitumor activity, blood-brain barrier permeability, and capability for tumor-specific drug deliverance and intraoperative visualization (termed theranostic) were of focus. Confocal microscopy was employed to characterize in vitro specificity of chlorotoxin, a 4 kDa scorpion venom peptide, and rBSG, the recombinant 25 kDa non-glycosylated extracellular domain of extracellular matrix metalloproteinase inducer (EMMPRIN; Basigin) isoform …


Exploring Empathy In Medical Narratives, Adam Uhrig Jul 2018

Exploring Empathy In Medical Narratives, Adam Uhrig

All NMU Master's Theses

No abstract provided.


Effects Of Norharmane And Nicotine On The Conditioned Place Preference Of Mice, Lindsey Galbo May 2018

Effects Of Norharmane And Nicotine On The Conditioned Place Preference Of Mice, Lindsey Galbo

All NMU Master's Theses

Tobacco smoking in the United States is used by approximately 25% of adults. Many studies using animal models have suggested that nicotine has rewarding properties. Contrastingly, several studies have also found it to be a weakly reinforcing substance at low and high dose levels. Due to this, other tobacco constituents, such as the monoamine oxidase inhibitor norharmane which is found in tobacco leaf and smoke, may be responsible for tobacco addiction by potentiating the rewarding properties of nicotine. Several studies have attempted to observe this phenomenon, however, monoamine oxidase inhibitors that are not found in tobacco leaf or smoke have …


Three Speeds Of Yoga And The Effects On Salivary Cortisol Levels In Female Nursing Students, Meagan Hennekens May 2018

Three Speeds Of Yoga And The Effects On Salivary Cortisol Levels In Female Nursing Students, Meagan Hennekens

All NMU Master's Theses

Purpose: Nursing students are prone to stress-related diseases, such as depression and anxiety, which are associated with chronically elevated cortisol levels due to the excessive firing of the Hypothalamic Pituitary Adrenal (HPA) axis. This study assessed three speeds of yoga and how they acutely affected salivary cortisol levels within female nursing students. Methods: Students participated in three yoga sessions cadenced at different speeds in a non-randomized order: (i) standard-speed yoga (SSY), (ii) high-speed yoga (HSY), and (iii) slow-speed yoga (SLSY). Each class integrated sequencing concepts from the brahmana/langhana strategy (BLS) and the Para Yoga Blueprint (PYB). Cortisol samples were …


Characterization Of The Roles Of Muscle-Synthesized Brain-Derived Neurotrophic Factor And Presynaptic Tyrosine Receptor Kinase B In Motor Neuron Axonal Transport, Luke A. Vanosdol Mar 2018

Characterization Of The Roles Of Muscle-Synthesized Brain-Derived Neurotrophic Factor And Presynaptic Tyrosine Receptor Kinase B In Motor Neuron Axonal Transport, Luke A. Vanosdol

All NMU Master's Theses

Brain-derived neurotrophic factor (BDNF) is a small, diffusible protein essential for the development and function of neurons. It is synthesized by many types of tissue, including muscle. BDNF actions are mediated via binding to its receptor, tyrosine receptor kinase B (TrkB). The BDNF-TrkB complex is endocytosed into a specialized vesicle, which induces downstream signaling cascades locally in the dendrites, or, more often, is delivered to the cell soma via retrograde axonal transport, where it modulates gene expression. BDNF activation of TrkB is critical for the initiation of axonal transport, and this cellular process relies on the interaction of numerous adaptor …