Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 8 of 8

Full-Text Articles in Medicine and Health Sciences

Investigation Of The Effects Of Prenatal Drug Exposure On Astrocyte-Mediated Synaptogenic Signaling, Taylor Christian Boggess Jan 2022

Investigation Of The Effects Of Prenatal Drug Exposure On Astrocyte-Mediated Synaptogenic Signaling, Taylor Christian Boggess

Theses, Dissertations and Capstones

One of the most significant outcomes of the rise in rates of opioid abuse in the United States has been a dramatic increase in the incidence of neonatal abstinence syndrome (NAS), the clinical diagnosis for the collection of withdrawal-like signs and symptoms commonly observed in the newborns of mothers who abused certain drugs, such as opioids, during pregnancy. While a great deal of research has investigated the short-term symptoms and potential treatments for NAS, including my own studies to identify emerging trends among a local population of NAS patients, there remains a critical need to investigate the long-term effects of …


From Crib To Bench: Understanding Neonatal Opioid Withdrawal Syndrome (Nows) Using A Novel Rodent Model, Sarah Stevens Jan 2021

From Crib To Bench: Understanding Neonatal Opioid Withdrawal Syndrome (Nows) Using A Novel Rodent Model, Sarah Stevens

Theses, Dissertations and Capstones

As the opioid epidemic continues to grow, opioid use among pregnant women is increasing significantly. This has led to a steady rise in the number of infants born with neonatal opioid withdrawal syndrome (NOWS). Although short-term withdrawal symptoms associated with NOWS are well characterized, there are many gaps in our understanding of the short and long-term effects of prenatal opioid exposure. In CHAPTER 1, we describe the clinical presentation, associated neurodevelopmental challenges, and current treatments of NOWS. Our current understanding of the neuropathology of NOWS is limited, and therefore further research is needed. However, current animal models are limited by …


From Darkness To Light: An Exploration Of Self-Discovery And Healing Through Collaborative Recovery Expressive Writing, Leighann Justice Davidson Jan 2019

From Darkness To Light: An Exploration Of Self-Discovery And Healing Through Collaborative Recovery Expressive Writing, Leighann Justice Davidson

Theses, Dissertations and Capstones

This participatory action research project was developed to explore the participants’ experiences during a collaborative recovery expressive writing (CREW) workshop while in long-term treatment from substance use disorders (SUDs). This workshop featured the primary components of the James W. Pennebaker model, but adapted the technique to create a safe environment for the participants to share their writings. This qualitative study conducted at Recovery Point West Virginia began by exploring how ten women sharing their emotions within a supportive environment used collaborative writing to continue their recovery journey through self-discovery and healing. Following the CREW workshop, the project continued with focus …


The State Of Neonatal Abstinence Syndrome In West Virginia, Sean Loudin Jul 2018

The State Of Neonatal Abstinence Syndrome In West Virginia, Sean Loudin

Marshall Journal of Medicine

No abstract provided.


Chasing The Dragon, Daniel Young Cho, Hani Nazha, Kalin Fisher Jan 2018

Chasing The Dragon, Daniel Young Cho, Hani Nazha, Kalin Fisher

Marshall Journal of Medicine

Abstract: Although rare, toxic leukoencephalopathy (TLE) associated with heroin inhalation have been reported. ‘Chasing the dragon’ may lead to progressive spongiform degeneration of the brain and presents with a large range of neuropsychological sequelae. A thorough social history and clinical suspicion are paramount in recognizing the diagnosis. This case is an example of TLE in a middle-aged white male with a history of polysubstance abuse. He presented with a three week history of progressive neuropsychological symptoms, including abulia, bradyphrenia, hyperreflexia, and visual hallucinations. He was initially suspected to have progressive multifocal leukoencephalopathy, however, JCV PCR was negative. MRI showed diffuse …


Opioid Epidemic-- Is There An End In Sight?, Sean Loudin, Mehiar El-Hamdani, Mohammed Ranavaya Oct 2017

Opioid Epidemic-- Is There An End In Sight?, Sean Loudin, Mehiar El-Hamdani, Mohammed Ranavaya

Marshall Journal of Medicine

No abstract provided.


Physician, Heal Thy Community, Clay B. Marsh Md Jul 2017

Physician, Heal Thy Community, Clay B. Marsh Md

Marshall Journal of Medicine

What if the opioid epidemic and the chronic health problems we encounter in West Virginia and beyond are a symptom of a deeper problem? How can we create healthcare to address the root issues here, and then spread these solutions globally?


The Crisis Of Opiates In Appalachia, James B. Becker Md Jan 2016

The Crisis Of Opiates In Appalachia, James B. Becker Md

Marshall Journal of Medicine

No abstract provided.