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Physician-Patient Communication About Genomic Tumor Testing: Perceptions Of Oncology Providers, Hayley Mandeville, Eric Anderson, Kimberly Murray, Caitlin Gutheil, Leo Waterston, Lee Lucas, Christine Duarte, Christian Thomas, Susan Miesfeldt, Petra Helbig, Andrey Antov, Jens Rueter, Paul Han
Physician-Patient Communication About Genomic Tumor Testing: Perceptions Of Oncology Providers, Hayley Mandeville, Eric Anderson, Kimberly Murray, Caitlin Gutheil, Leo Waterston, Lee Lucas, Christine Duarte, Christian Thomas, Susan Miesfeldt, Petra Helbig, Andrey Antov, Jens Rueter, Paul Han
Maine Medical Center
Background:
• Genomic tumor testing (GTT) is a new technology and a cornerstone of the “precision medicine” movement in cancer care.
• GTT uses next-generation genome sequencing technology to identify somatic variants in tumor cells.
• By identifying somatic variants that predict responses to cancer therapies, GTT can help tailor therapy to individual patients, making them more effective.
• However, due to the fact that GTT also detects many variants of uncertain significance, its clinical value is currently unproven.
• When using GTT, physicians counsel patients about both its benefits and its limitations, but the ideal goals and content of …