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Articles 1 - 30 of 57
Full-Text Articles in Medicine and Health Sciences
Insulin Signaling In Osteocytes In Bone Development, Vivin Karthik
Insulin Signaling In Osteocytes In Bone Development, Vivin Karthik
Costas T. Lambrew Research Retreat 2021
Hypothesis: IRS1/2 signaling is necessary for osteocyte development and function
Control Of Perivascular Adipose Tissue Differentiation During Cardiovascular Disease, Katie Stieber
Control Of Perivascular Adipose Tissue Differentiation During Cardiovascular Disease, Katie Stieber
Costas T. Lambrew Research Retreat 2021
Hypothesis: Lower BMI will correlate with lower RAB27a expression
Determinants Of Private Well Water Testing In Maine, Jenny Carwile, Shravanthi M. Seshasayee, Kritika Anand, Abby F. Fleisch
Determinants Of Private Well Water Testing In Maine, Jenny Carwile, Shravanthi M. Seshasayee, Kritika Anand, Abby F. Fleisch
Costas T. Lambrew Research Retreat 2021
Objectives: Describe sociodemographic characteristics associated with ever testing well water using data from the 2014-2017 Maine Behavioral Risk Factor Surveillance System (BRFSS) (n= 12,152).
Inhibiting Fatty Acid Binding Protein Family Members Decreases Multiple Myeloma Cell Proliferation Through Effecting The Myc Pathway, Mariah Farrell, Heather Fairfield, Anastasia D'Amico, Carolyne Falank, Connor Murphy, Michaela Reagan
Inhibiting Fatty Acid Binding Protein Family Members Decreases Multiple Myeloma Cell Proliferation Through Effecting The Myc Pathway, Mariah Farrell, Heather Fairfield, Anastasia D'Amico, Carolyne Falank, Connor Murphy, Michaela Reagan
Costas T. Lambrew Research Retreat 2021
FABP inhibition leads to increased survival of myeloma bearing mice and decreased cell growth by inhibiting MYC signaling.
Institutional Experience With Primary Interventional Radiology Sclerotherapy For Lymphatic Malformation, Obiyo Osuchukwu, Brenton Reading, Charlene Dekonenko, Wendy Jo Svetanoff, Jeff Thekkekara, Douglas C. Rivard, Charles L. Snyder, Tolulope A. Oyetunji
Institutional Experience With Primary Interventional Radiology Sclerotherapy For Lymphatic Malformation, Obiyo Osuchukwu, Brenton Reading, Charlene Dekonenko, Wendy Jo Svetanoff, Jeff Thekkekara, Douglas C. Rivard, Charles L. Snyder, Tolulope A. Oyetunji
Costas T. Lambrew Research Retreat 2021
Interventional Radiology Sclerotherapy is effective for treatment of primary and recurrent lymphatic malformations
Plasma Concentrations Of Per- And Polyfluoroalkyl Substances And Body Composition From Mid-Childhood To Early Adolescence, Jaclyn Janis, Sheryl Rifas-Shiman, Shravanthi M. Seshasayee, Clifford J Rosen, Abby F Fleisch, Sharon Sagiv, Emily Oken
Plasma Concentrations Of Per- And Polyfluoroalkyl Substances And Body Composition From Mid-Childhood To Early Adolescence, Jaclyn Janis, Sheryl Rifas-Shiman, Shravanthi M. Seshasayee, Clifford J Rosen, Abby F Fleisch, Sharon Sagiv, Emily Oken
Costas T. Lambrew Research Retreat 2021
BACKGROUND
• Per- and polyfluoroalkyl substances (PFAS) may alter body composition by lowering anabolic hormones and increasing inflammation.
Prior studies have found positive, inverse, and null associations of PFAS concentrations with adiposity among children and adolescents.
Few studies have examined associations of PFAS concentrations with changes in body composition longitudinally.
No study has examined the association of PFAS plasma concentrations with lean mass.
The Effect Of High Fat Diet On Marrow Adipocytes From C57bl/6j (B6) Mice, Gisela Pachón-Peña, Clifford J. Rosen, Samantha Costa
The Effect Of High Fat Diet On Marrow Adipocytes From C57bl/6j (B6) Mice, Gisela Pachón-Peña, Clifford J. Rosen, Samantha Costa
Costas T. Lambrew Research Retreat 2021
In mice models, the administration of a high fat diet (HFD) is an accelerating factor for metabolic syndrome, impaired glucose tolerance, and early type 2 diabetes mellitus (T2DM) (1)
Preventive Healthcare Services Receipt And Primary Care Provider Utilization Among People Who Inject Drugs, E K. Nenninger, Kinna Thakarar
Preventive Healthcare Services Receipt And Primary Care Provider Utilization Among People Who Inject Drugs, E K. Nenninger, Kinna Thakarar
Costas T. Lambrew Research Retreat 2021
Introduction:
People who inject drugs (PWID) face barriers to accessing primary care providers (PCPs) and preventive services, but are at increased risk for preventable infections
Preventive services can be accessed through PCPs, or while hospitalized or at community organizations like syringe service programs (SSPs)
Ketamine Infusions For Post-Cesarean Pain In Patients With Opioid Use Disorder, Talitha Budi, Johanna Cobb, Wendy Craig, Heather Turcotte, Janelle Richard, Aurora Quaye
Ketamine Infusions For Post-Cesarean Pain In Patients With Opioid Use Disorder, Talitha Budi, Johanna Cobb, Wendy Craig, Heather Turcotte, Janelle Richard, Aurora Quaye
Costas T. Lambrew Research Retreat 2021
Discussion:
• Opioid consumption may be reduced during ketamine infusion without significant side effects
• Further investigation planned with a prospective, randomized, double-blind, placebo-controlled trial.
Standardized Ekg Curriculum, Michael Ellerman, Jon Nichols, Sanjeev Francis
Standardized Ekg Curriculum, Michael Ellerman, Jon Nichols, Sanjeev Francis
Costas T. Lambrew Research Retreat 2021
Goal: To study the effect of a standardized EKG curriculum on competency of interpreting common EKGs among internal medicine residents
Boot Camp Translation: Community Engaged Research Process Evaluation, Emma Daybranch, Kerri Barton, Brendan Schauffler, Lisbeth Wierda, Neil Korsen
Boot Camp Translation: Community Engaged Research Process Evaluation, Emma Daybranch, Kerri Barton, Brendan Schauffler, Lisbeth Wierda, Neil Korsen
Costas T. Lambrew Research Retreat 2021
The BCT process was first developed by the High Plains Research Network and its Community Advisory Council in rural Colorado. Between 2004 and 2015 the BCT process was used 31 times across the U.S. on a broad range of topics.
Tusm–Mmc Maine Track: Undergraduate Medical Education Teaching Partnership 2021, Maine Medical Center
Tusm–Mmc Maine Track: Undergraduate Medical Education Teaching Partnership 2021, Maine Medical Center
Annual Reports
2021 Program Report
Anterior-Based Muscle Sparing Approach For Total Hip Arthroplasty, Callahan M. Sturgeon, George M. Babikian, Brian J. Mcgrory, Adam J. Rana
Anterior-Based Muscle Sparing Approach For Total Hip Arthroplasty, Callahan M. Sturgeon, George M. Babikian, Brian J. Mcgrory, Adam J. Rana
Costas T. Lambrew Research Retreat 2021
A high value, high quality and low cost surgery: a 7.5 year single-center, retrospective case series
Impact Of Bowel Management Guidelines On Documentation And Patient Outcomes In The Intensive Care Unit, Alana Trottier, Paul Blakeslee, Kristiina Hyrkas
Impact Of Bowel Management Guidelines On Documentation And Patient Outcomes In The Intensive Care Unit, Alana Trottier, Paul Blakeslee, Kristiina Hyrkas
Costas T. Lambrew Research Retreat 2021
Introduction
• Bowel management (BM) is an inadvertently overlooked aspect of patient care for critically ill patients who have complex, immediate life-threatening health issues.
• Bowel dysfunction is common with the reported incidence of diarrhea between 3.3%-78% and constipation between 20-83%
• Studies suggest that BM guidelines can standardize care, improve documentation, and impact patient outcomes
• Use of BM guidelines has remained low, probably influenced by clinicians’ resistance to change, resulting in small to moderate improvements and difficulties sustaining new practices
• We anticipated that sustained changes require recognizing clinicians’ current practice, integrating modifications into existing workflow, and engaging …
An Evaluation Of The Rollout Of Aunt Bertha, A Community-Centered Directory, Across The Mainehealth Network, Samantha Dinsdale, Lisbeth Wierda, Kerri Barton, Ellen Freedman
An Evaluation Of The Rollout Of Aunt Bertha, A Community-Centered Directory, Across The Mainehealth Network, Samantha Dinsdale, Lisbeth Wierda, Kerri Barton, Ellen Freedman
Costas T. Lambrew Research Retreat 2021
Remote interviews were conducted with community-based organizations across Maine to gain insight to their perspective of Aunt Bertha’s use and potential.
Development Of Maine Ongoing Outreach Simulation Education (Moose), A Novel Telesimulation Program, To Improve Neonatal Resuscitation In A Rural Community Hospital, Allison Zanno, Misty Melendi, Micheline Chipman, Jeffrey Holmes, Alexa Craig, Samantha Piro, Anna Gilbert, Sarah Gabrielson, Leah Mallory, Anya Culter, Mary Ottolini
Development Of Maine Ongoing Outreach Simulation Education (Moose), A Novel Telesimulation Program, To Improve Neonatal Resuscitation In A Rural Community Hospital, Allison Zanno, Misty Melendi, Micheline Chipman, Jeffrey Holmes, Alexa Craig, Samantha Piro, Anna Gilbert, Sarah Gabrielson, Leah Mallory, Anya Culter, Mary Ottolini
Costas T. Lambrew Research Retreat 2021
Objective- To implement monthly neonatal resuscitation telesimulation team training sessions in a rural community hospital delivery room that is feasible, sustainable, and replicable at other sites.
A Period Seroprevalence (Sars-Cov-2) Survey In Mhccn Cancer Healthcare Workers (Hcws) Providing Patient Care During The Height Of The Outbreak: A Registry Study (Initial Progress), Jill Prescott, Caroline Knight, Erin Hobart, Jamie Saunders, Kimberly Caron, Sandra Neptune, Patty Brown, Lisa Lemire, Anne Breggia, Susan L. Guierin-Staples, Lee Lucas, Paul Han, Rachit Kumar, Robert Carlson, Scot Remick
A Period Seroprevalence (Sars-Cov-2) Survey In Mhccn Cancer Healthcare Workers (Hcws) Providing Patient Care During The Height Of The Outbreak: A Registry Study (Initial Progress), Jill Prescott, Caroline Knight, Erin Hobart, Jamie Saunders, Kimberly Caron, Sandra Neptune, Patty Brown, Lisa Lemire, Anne Breggia, Susan L. Guierin-Staples, Lee Lucas, Paul Han, Rachit Kumar, Robert Carlson, Scot Remick
Costas T. Lambrew Research Retreat 2021
Introduction: There is little information on the basic epidemiologic and serologic profile(s) of the novel SARSCoV- 2 coronavirus especially in HCWs employed in rural settings. We embarked on a period seroprevalence study in the MaineHealth Cancer Network (MHCCN) to document Covid-19 exposure in our rural cancer care workforce. Our fundamental hypothesis is that despite implementing procedures to safeguard patients and the use of appropriate PPE in the care of known source patients/PUIs in both the inpatient and outpatient cancer care settings a small, but not insignificant number of cancer care providers (hereafter referred to as cancer HCWs) will have evidence …
Impact Of A Primary Care Clinical Pharmacist On The Management Of Hepatitis C Viral Infection, Sierra Ferreiira, Adam Normandin, Linh Gagnon, Corinn Martineau
Impact Of A Primary Care Clinical Pharmacist On The Management Of Hepatitis C Viral Infection, Sierra Ferreiira, Adam Normandin, Linh Gagnon, Corinn Martineau
Costas T. Lambrew Research Retreat 2021
Interprofessional care including a pharmacist demonstrates a positive trend towards increasing access to care and improving adherence to Hepatitis C management in a primary care setting.
Resilience Of Regional Hospital Nursing Staff Working During The Covid-19 Pandemic Measured By The Connor-Davidson Resilience Scale, Jill Petzel Baer
Resilience Of Regional Hospital Nursing Staff Working During The Covid-19 Pandemic Measured By The Connor-Davidson Resilience Scale, Jill Petzel Baer
Costas T. Lambrew Research Retreat 2021
Low resilience is widespread in nursing staff during the COVID-19 pandemic
Investigation Of The Relationship Between Obesity, Weight Cycling, And Tumor Progression In Murine Myeloma Models, Heather Fairfield, Catherine R. Marinac, Mariah Farrell, Brenda M. Birmann, Michaela R. Reagan
Investigation Of The Relationship Between Obesity, Weight Cycling, And Tumor Progression In Murine Myeloma Models, Heather Fairfield, Catherine R. Marinac, Mariah Farrell, Brenda M. Birmann, Michaela R. Reagan
Costas T. Lambrew Research Retreat 2021
We investigated this relationship in two murine myeloma models with a high fat diet (HFD) to induce obesity, and a diet cycling (DC) regimen to model weight cycling.
Perceptions Of Self-Efficacy And Experiences Of Mindfulness On Pain And Anxiety In Patients Undergoing A Colorectal Surgery: A Prospective Mixed Methods Study, Rebecca Brown, Julie Fitzgibbons, Rachel Farrington
Perceptions Of Self-Efficacy And Experiences Of Mindfulness On Pain And Anxiety In Patients Undergoing A Colorectal Surgery: A Prospective Mixed Methods Study, Rebecca Brown, Julie Fitzgibbons, Rachel Farrington
Costas T. Lambrew Research Retreat 2021
Introduction
• Pain and anxiety have a physiological response on the body.
• Increased heart rate, respiratory rate and blood pressure can lead to complications, and thus longer hospitalization along with decreased patient satisfaction.
Facilitators And Barriers To Accessing Harm Reduction Services In A Rural State, Kinna Thakarar, Michael Kohut, Deb Burris, Hannah Loeb, Rebecca Hutchinson, Kathleen Fairfield
Facilitators And Barriers To Accessing Harm Reduction Services In A Rural State, Kinna Thakarar, Michael Kohut, Deb Burris, Hannah Loeb, Rebecca Hutchinson, Kathleen Fairfield
Costas T. Lambrew Research Retreat 2021
INTRODUCTION
• The impact of social distancing policies during the COVID-19 pandemic on people who inject drugs (PWID) is not known.
• We aimed to describe the impact of the pandemic on PWID access to harm reduction services in Maine
Novel Roles Of Mir-199b In Regulating Fat And Bone Metabolism, Aldona Karaczyn, Victoria Demambro, Jennifer Daruszka, Patrizia Roy, Clifford Rosen, Calvin Vary
Novel Roles Of Mir-199b In Regulating Fat And Bone Metabolism, Aldona Karaczyn, Victoria Demambro, Jennifer Daruszka, Patrizia Roy, Clifford Rosen, Calvin Vary
Costas T. Lambrew Research Retreat 2021
Public Health Problem:
The incidence of obesity has reached epidemic proportions worldwide and has contributed to an increase in the risk of numerous chronic disorders-type 2 diabetes-liver pathologies, dyslipidemia, and cardiovascular diseases.
Obesity can have negative effects on bone remodeling-reduced mineral density-osteoporosis
Imbalance between food intake and energy expenditure-obesity-accumulation of fat mass and energy storage in white adipose tissue (WAT).
Parent Experience Of Hie And Hypothermia: A Call For Trauma Informed Care, Anna Sagaser, Betsy Pilon, Annie Goeller, Monica Lemmon, Alexa Craig
Parent Experience Of Hie And Hypothermia: A Call For Trauma Informed Care, Anna Sagaser, Betsy Pilon, Annie Goeller, Monica Lemmon, Alexa Craig
Costas T. Lambrew Research Retreat 2021
Objective:
To assess parents’ experience of communication with the medical team and involvement with their infant during HIE treatment.
A New Project Echo Focused On Clinical Research In Development By The Nne-Ctr, Ivette Emery, Kerri Barton, Meredith Oestreicher, Neil Korsen, Irwin Brodsky
A New Project Echo Focused On Clinical Research In Development By The Nne-Ctr, Ivette Emery, Kerri Barton, Meredith Oestreicher, Neil Korsen, Irwin Brodsky
Costas T. Lambrew Research Retreat 2021
I diagram presented for the project by the NNE-CTR
Phq 9 Utilization In Maine Health, Steven Gerrish, Kerri Barton, Neil Korsen
Phq 9 Utilization In Maine Health, Steven Gerrish, Kerri Barton, Neil Korsen
Costas T. Lambrew Research Retreat 2021
The PHQ is a brief patient survey for diagnosing depression and monitoring response to treatment.
Notch Signaling Regulates Perivascular Adipose Tissue (Pvat) Function During Diet-Induced Obesity, C Yang, A Harrington, L Ryzhova, L Liaw
Notch Signaling Regulates Perivascular Adipose Tissue (Pvat) Function During Diet-Induced Obesity, C Yang, A Harrington, L Ryzhova, L Liaw
Costas T. Lambrew Research Retreat 2021
Objectives:
-To test the hypothesis that canonical Notch signaling influence vascular function by regulating PVAT-derived vascular relaxation factors.
-To determine how overexpression of Notch signaling or loss of the key Notch signaling component influence PVAT function.
Improving Diabetic Retinopathy Screening Rate In A Rural Primary Care Setting Using Point Of Care Ai Technology, Shane Kirkegaard
Improving Diabetic Retinopathy Screening Rate In A Rural Primary Care Setting Using Point Of Care Ai Technology, Shane Kirkegaard
Costas T. Lambrew Research Retreat 2021
Point of Care AI Technology Poised to Improve Diabetic Retinopathy Screening Rate in Rural Primary Care Setting
Multiple Myeloma Cells Graphs And Figures Inhibit Adipogenesis, Increase Senescencerelated And Inflammatory Gene Transcript Expression, And Alter Metabolism In Preadipocytes, Michaela R. Reagan, Heather Fairfield, Samantha Costa, Carolyne Falank, Mariah Farrell, Connor S. Murphy, Anastasia D'Amico, Heather Driscoll
Multiple Myeloma Cells Graphs And Figures Inhibit Adipogenesis, Increase Senescencerelated And Inflammatory Gene Transcript Expression, And Alter Metabolism In Preadipocytes, Michaela R. Reagan, Heather Fairfield, Samantha Costa, Carolyne Falank, Mariah Farrell, Connor S. Murphy, Anastasia D'Amico, Heather Driscoll
Costas T. Lambrew Research Retreat 2021
Myeloma cells alter metabolism & induce senescence in adipocyte-lineage cells, suggesting that senescence-associated proteins are involved in multiple myeloma.
Naloxone Co-Prescribing Across A Large Health System: A Quality Improvement Project, Marc D. Kimball, Sarah Hemphill, Kristen Silvia
Naloxone Co-Prescribing Across A Large Health System: A Quality Improvement Project, Marc D. Kimball, Sarah Hemphill, Kristen Silvia
Costas T. Lambrew Research Retreat 2021
Introduction:
• Naloxone availability and administration saves lives
• The CDC recommends naloxone co-prescribing for patients with OUD and other eligibility criteria
• Maine Medical Center’s baseline was found to be 6% in one clinic. This held true across the entire MaineHealth system.