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Full-Text Articles in Medicine and Health Sciences

Il-1Β Enhances Cell Viability And Decreases 5-Fu Sensitivity In Novel Colon Cancer Cell Lines Derived From African American Patients, Marzia Spagnardi, Jenny Paredes, Jovanny Zabaleta, Jone Garai, Tiana Reyes, Laura A. Martello, Jennie L. Williams Dec 2022

Il-1Β Enhances Cell Viability And Decreases 5-Fu Sensitivity In Novel Colon Cancer Cell Lines Derived From African American Patients, Marzia Spagnardi, Jenny Paredes, Jovanny Zabaleta, Jone Garai, Tiana Reyes, Laura A. Martello, Jennie L. Williams

School of Medicine Faculty Publications

Background: In the U.S., African Americans (AAs) present with the highest incidence and mortality rates for Colorectal Cancer (CRC). When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). Here, we investigate the role of IL-1β in modifying chemotherapeutic response and altering expression of proteins in novel AA …


Understanding Perinatal Patient’S Health Preferences And Patient-Provider Relationships To Prevent Congenital Syphilis In California And Louisiana, Jennifer A. Wagman, Eunhee Park, Gloria P. Giarratano, Pierre M. Buekens, Emily W. Harville Jul 2022

Understanding Perinatal Patient’S Health Preferences And Patient-Provider Relationships To Prevent Congenital Syphilis In California And Louisiana, Jennifer A. Wagman, Eunhee Park, Gloria P. Giarratano, Pierre M. Buekens, Emily W. Harville

School of Nursing Faculty Publications

Background: Congenital syphilis (CS) has reemerged as a global maternal and child health crisis. Kern County, California and East Baton Rouge Parish, Louisiana are among the highest CS morbidity regions in the United States. We previously reported on social-ecological and structural barriers to prenatal care and maternal syphilis testing and treatment in these two regions. The aim of this study was to examine perinatal patient’s health preferences and perceptions of patient-provider relationships in the prenatal care clinic setting. Methods: Between May 2018 and January 2019 we conducted 20 in-depth qualitative interviews with prenatal providers and 8 focus group discussions with …


The Covid-19 Pandemic And Associated Increases In Experiences Of Assault Violence Among Black Men With Low Socioeconomic Status Living In Louisiana, Kaylin Beiter, Denise Danos, Erich Conrad, Stephanie Broyles, Jovanny Zabaleta, Jason Mussell, Stephen Phillippi Jul 2022

The Covid-19 Pandemic And Associated Increases In Experiences Of Assault Violence Among Black Men With Low Socioeconomic Status Living In Louisiana, Kaylin Beiter, Denise Danos, Erich Conrad, Stephanie Broyles, Jovanny Zabaleta, Jason Mussell, Stephen Phillippi

School of Public Health Faculty Publications

Background: The COVID-19 pandemic has had mental health, social, and economic implications among communities with high levels of social disadvantage; this may have impacted community violence rates. The objective of this study was to characterize overall trends in assault and social disadvantage of patients experiencing assault before and during the COVID-19 pandemic. Methods: All trauma activations at a level one trauma center serving the entire southeast Louisiana region were included during March–August pre-COVID (2018–2019) and during COVID (2020). ICD-10 E-codes were used to identify trauma intent (assault vs. other). Assaults in this context are defined as physical injuries caused by …


Editorial: The Interplay Between Social Determinants Of Health And Cancer Related Health Disparities, Tung-Sung Tseng, Chien Ching Li, Alicia K. Matthews May 2022

Editorial: The Interplay Between Social Determinants Of Health And Cancer Related Health Disparities, Tung-Sung Tseng, Chien Ching Li, Alicia K. Matthews

School of Public Health Faculty Publications

No abstract provided.