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Full-Text Articles in Medicine and Health Sciences
Synergistic Neuroprotection By A Paf Antagonist Plus A Docosanoid In Experimental Ischemic Stroke: Dose-Response And Therapeutic Window, Madigan M. Reid, Andre Obenaus, Pranab K. Mukherjee, Larissa Khoutorova, Cassia R. Roque, Nicos A. Petasis, Reinaldo B. Oria, Ludmila Belayev, Nicolas G. Bazan
Synergistic Neuroprotection By A Paf Antagonist Plus A Docosanoid In Experimental Ischemic Stroke: Dose-Response And Therapeutic Window, Madigan M. Reid, Andre Obenaus, Pranab K. Mukherjee, Larissa Khoutorova, Cassia R. Roque, Nicos A. Petasis, Reinaldo B. Oria, Ludmila Belayev, Nicolas G. Bazan
School of Graduate Studies Faculty Publications
Objective: We tested the hypothesis that blocking pro-inflammatory platelet-activating factor receptor (PAFR) with LAU-0901 (LAU) plus administering a selected docosanoid, aspirin-triggered neuroprotectin D1 (AT-NPD1), which activates cell-survival pathways after middle cerebral artery occlusion (MCAo), would lead to neurological recovery. Dose-response and therapeutic window were investigated. Materials and methods: Male SD rats were subjected to 2 hours of MCAo. Behavior testing (days 1-7) and ex vivo MRI on day 7 were conducted. In dose-response, rats were treated with LAU (45 and 60 mg/kg; IP), AT-NPD1 (111, 222, 333 µg/kg; IV), LAU+AT-NPD1 (LAU at 3 hours and AT-NPD1 at 3.15 hours) or …
Factors Influencing Family Health History Collection Among Young Adults: A Structural Equation Modeling, Ming Li, Shixi Zhao, Yu Yu Hsiao, Oi Man Kwok, Tung-Sung Tseng, Lei Shih Chen
Factors Influencing Family Health History Collection Among Young Adults: A Structural Equation Modeling, Ming Li, Shixi Zhao, Yu Yu Hsiao, Oi Man Kwok, Tung-Sung Tseng, Lei Shih Chen
School of Public Health Faculty Publications
Family health history (FHH) can serve as an entry point for preventive medicine by providing risk estimations for many common health conditions. College is a critical time for young adults to begin to understand the value of FHH collection, and to establish healthy behaviors to prevent FHH-related diseases. This study seeks to develop an integrated theoretical framework to examine FHH collection behavior and associated factors among college students. A sample of 2670 college students with an average age of 21.1 years completed a web-based survey. Less than half (49.8%) reported actively seeking FHH information from their family members. Respondents’ knowledge …