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Himmelfarb Health Sciences Library, The George Washington University

Anesthesiology and Critical Care Medicine Faculty Publications

Biomarkers--blood

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Full-Text Articles in Medicine and Health Sciences

Renal Angina: Concept And Development Of Pretest Probability Assessment In Acute Kidney Injury, Lakhmir S. Chawla, Stuart L. Goldstein, John A. Kellum, Claudio Ronco Feb 2015

Renal Angina: Concept And Development Of Pretest Probability Assessment In Acute Kidney Injury, Lakhmir S. Chawla, Stuart L. Goldstein, John A. Kellum, Claudio Ronco

Anesthesiology and Critical Care Medicine Faculty Publications

The context of a diagnostic test is a critical component for the interpretation of its result. This context defines the pretest probability of the diagnosis and forms the basis for the interpretation and value of adding the diagnostic test. In the field of acute kidney injury, a multitude of early diagnostic biomarkers have been developed, but utilization in the appropriate context is less well understood and has not been codified until recently. In order to better operationalize the context and pretest probability assessment for acute kidney injury diagnosis, the renal angina concept was proposed in 2010 for use in both …