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Full-Text Articles in Medicine and Health Sciences

Alzheimer's Disease, Dylan L. Weber Oct 2022

Alzheimer's Disease, Dylan L. Weber

Student Publications

An overview of the background, etiology, pathophysiology, clinical features, diagnosis, treatment and prevention of Alzheimer's disease.


Age Related Macular Degeneration, Kathryn J. Hopsicker Oct 2022

Age Related Macular Degeneration, Kathryn J. Hopsicker

Student Publications

This paper is a literature review on the subject Age-Related Macular Degeneration (AMD) with a focus on its etiology, pathophysiology, clinical features, diagnosis, treatment, and prevention. AMD is the leading cause of severe and irreversible central vision loss in in individuals over the age of 55. There are two subtypes of AMD referred to as dry and wet respectively. The etiology of this disease is multifactorial and complex, with no hallmark of disease definitively identified. The distinct pathophysiological features differing in dry and wet AMD are explored in this review as well as its diagnosis and treatment. This disease is …


Brown Adipose Tissue (Bat) Activation And Its Potential Utilization As A Treatment Option For Obesity And Diabetes, Darcie B. Schneider Apr 2022

Brown Adipose Tissue (Bat) Activation And Its Potential Utilization As A Treatment Option For Obesity And Diabetes, Darcie B. Schneider

Student Publications

Within the human body, there are two types of adipose tissue: white adipose tissue (WAT) and brown adipose tissue (BAT). WAT is beneficial for insulation whereas BAT has thermogenic capacity. BAT activation increases energy consumption via heat generation. Increased energy expenditure is associated with improved glucose and lipid metabolism. Therefore, BAT activation research has primarily been aimed at its potential use in the treatment of obesity, diabetes, and other metabolic disorders. In this literature review, BAT's thermogenic mechanisms, techniques of activation, potential therapeutic targets, and future research topics are explored.


Extreme Exposure To Cold: A Method To Enhance Physical Wellness And Recovery, Mallory E. Duggan Apr 2022

Extreme Exposure To Cold: A Method To Enhance Physical Wellness And Recovery, Mallory E. Duggan

Student Publications

This paper reviews the current literature on Cryotherapy and its ability to enhance physical wellness and recovery. The paper details the proposed mechanisms of Cryotherapy as well as its various clinical applications regarding the treatment of numerous diseases and physical exercise recovery. The paper also details the possible limitations/detrimental effects of Cryotherapy usage.


Water Intoxication: Current Developments In Hyponatremia, Allison C. Mosmiller Apr 2022

Water Intoxication: Current Developments In Hyponatremia, Allison C. Mosmiller

Student Publications

This paper is a review of recent research on the subject of exercise-associated hyponatremia. Hyponatremia is notoriously difficult to diagnose and to treat due to its general symptoms and required specificity in diagnosis in order to assign appropriate treatment. If left untreated, Hyponatremia can result in the development of complications like cerebral edema, seizures, coma, and sometimes death. The pathogenesis of hyponatremia includes multiple proposed mechanisms, including overconsumption of hypotonic fluids, inappropriate release of antidiuretic hormone, inefficiency of fluid filtration by the kidneys, redirection of fluid into intestinal lumen, and activation of the renin-angiotensin-aldosterone system. Signs and symptoms of hyponatremia …


Brown Fat In Humans: The Significance Of Thermogenic Active Tissue, Brett T. Swanson Apr 2022

Brown Fat In Humans: The Significance Of Thermogenic Active Tissue, Brett T. Swanson

Student Publications

Brown adipose tissue is a metabolically active form of fat in the body that performs a crucial function in non-shivering thermogenesis. It can be compared to the prevalent white adipose tissue which is generally understood to be energy storage in the body, with brown tissue performing an opposing role. The tissue itself contains unique gene and protein markers such as uncoupling protein 1 (UCP1) which allows for the thermogenic process inside the cell, burning lipids to do so. These gene and protein markers have proven to be crucial in the detection of brown adipose tissue, which had previously been thought …


Oxygen Deprivation Masks For Training, Brittany M. Hanlon Apr 2022

Oxygen Deprivation Masks For Training, Brittany M. Hanlon

Student Publications

Oxygen deprivation masks are being advertised towards athletes as a piece of fitness equipment that can simulate the effects of high altitude, as well as a respiratory muscle training device. Studies that investigated the claims as to whether ODMs increased VO2max and improved endurance were looked into. Experimental data did not find that the use of these masks increased VO2max, nor was there any supporting data to prove that it improved endurance. The function of ODMs as a training tool to increase respiratory muscle strength was also examined. There were contradicting results between the three different studies examined. One study …


Epidemiology In Higher Education: Scarlet Fever At Gettysburg College, Addison E. Lomax Apr 2022

Epidemiology In Higher Education: Scarlet Fever At Gettysburg College, Addison E. Lomax

Student Publications

Throughout the early 20th century, the relationship between higher education and the spread of epidemic disease evolved in the United States. Two notable epidemics of scarlet fever in 1915 and 1920 serve as a lens through which the larger roles of disease and higher education can be analyzed. By assessing the roles both the administration and the students played at Gettysburg College, then Pennsylvania College, historians can understand the process of combating health crises in the future. Although the Pennsylvania College scarlet fever epidemics of 1915 and 1920 impacted campus to a smaller extent than the 2020 COVID-19 pandemic, the …


Hyperbaric Oxygen Therapy And Wound Healing, Karen E. Lucero Ortega Apr 2022

Hyperbaric Oxygen Therapy And Wound Healing, Karen E. Lucero Ortega

Student Publications

Hyperbaric Oxygen Therapy (HBOT) has been around since the 1860s and is now a well-established form of treatment. HBOT has been proven to be a safe therapeutic option and has been successful in treating non-healing wounds, traumatic wounds, and radiation-induced wounds. There has also been success in treating other conditions such as inflammatory bowel disease, carbon monoxide poisoning, and decompression sickness with HBOT. The way HBOT works is by exposing the body to 100% pure oxygen in a closed chamber, which exceeds normal atmospheric pressure by two to three times. With HBOT, large amounts of oxygen enters the body, which …