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Articles 1 - 11 of 11
Full-Text Articles in Medicine and Health Sciences
Analysis Of The Genetic And Neurological Components Of Opioid Addiction, With Public Health Perspectives Of The Opioid Epidemic In The United States Of America, Janhavi A. Dubhashi
Analysis Of The Genetic And Neurological Components Of Opioid Addiction, With Public Health Perspectives Of The Opioid Epidemic In The United States Of America, Janhavi A. Dubhashi
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Opioid addiction has reached epidemic levels around the world, with over-prescription of opioid pain relievers being an often-cited reason for the epidemic in the USA. This project looks at opioid addiction from three perspectives: a review of literature dealing with the neural pathways involved in opioid use and addiction; the underlying genetic differences that can increase the risk of opioid use disorder; and an overview of the public health aspects of the epidemic. The paper will conclude with a review of current and new treatments based upon a growing neurobiological and molecular understanding of opioid use disorder.
The Effects Of Adaptogens On The Physical And Psychological Symptoms Of Chronic Stress, Tosin O. Ajala
The Effects Of Adaptogens On The Physical And Psychological Symptoms Of Chronic Stress, Tosin O. Ajala
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Stress is a state of disharmony or threatened homeostasis. The maintenance of homeostasis in stages of internal or external challenges, called stressors, requires constant adjustments of hormonal, behavioral, and autonomic functions. The nuances of life may bring about unwanted stress to the human body. Some of the top causes of stress in America include work, finances, relationships, and health. There are numerous physical and psychological symptoms associated with long-term “chronic” stress, which include chronic fatigue, frustration, irritability, insomnia, frequent headaches, chest and back pain, weakness, and weight gain or weight loss. These symptoms of chronic stress are associated with depression, …
Skin Bleaching In South Africa: A Result Of Colonialism And Apartheid?, Nahomie Julien
Skin Bleaching In South Africa: A Result Of Colonialism And Apartheid?, Nahomie Julien
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
South Africans have not overcome many of the psychological effects of apartheid and colonialism, some of which are self-hatred and low self-esteem. These negative psychosomatic influences often push people to alter their physical appearance to feel better about themselves, and one of the most common methods of doing so is by bleaching the skin(Abrahams, 2000; Charles, 2003; Singham, 1968). Skin bleaching, the application of topical creams, gels, soaps, and household products (e.g., toothpaste, bleach, washing powder, battery acid) to lighten the skin, has become one of the most common forms of potentially harmful body modification practices in the world within …
Post-Apartheid South Africa’S Ultimate Challenge, Nahomie Julien
Post-Apartheid South Africa’S Ultimate Challenge, Nahomie Julien
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Throughout time, South Africa has experienced many upheavals, be they slavery and apartheid or natural, socioeconomic, and political misfortunes.Just after overcoming the oppression of Apartheid, South Africans have to face one of the deadliest illness in the world: HIV/AIDS. HIV/AIDS is currently the number one killer in South Africa(WHO, 2012). This pandemic further worsen the struggles of the nation, obstructing its educational, financial, and political recovery (Oglethorpe, & Gelman, (2008).; Weiser, et al., 2007.). This paper seeks to analyze how apartheid—or rather, its demise—contributed to the alarmingly rapid spread of this pandemic in South Africa. In so doing, the current …
Relationship Of Body Mass Index And Activity Level With Sleep Quality Among College Women, Caroline Wuertz, Yesmira Chia, Jiwon Lee
Relationship Of Body Mass Index And Activity Level With Sleep Quality Among College Women, Caroline Wuertz, Yesmira Chia, Jiwon Lee
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Introduction: The effects of obesity and a sedentary lifestyle on overall health have been thoroughly researched. It is also common for college women to prioritize studying over healthy sleeping habits. However, little is known regarding Body Mass Index (BMI) and activity level and their relationship with sleep quality among college women. Determining these relationships would be beneficial in educating college women about the implications of their behaviors. Purpose: The purpose of this study is to: 1) explore the relationship between BMI and sleep quality, and 2) examine the relationship between levels of physical activity and sleep quality among college women. …
Investigating The Solvation, Binding Mode, And Free Energy Of A Minor Groove Dna Complex Using Atomistic Computer Simulations, Keon Reid
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Two helical (alpha and beta) strands form DNA. The DNA structural background provides grooves which may act as a binding site. The major groove is 22 Å wide whereas the minor groove is 12 Å wide. The minor groove of the double-stranded DNA can interact with many different classes of ligands in a sequence specific fashion. Netropsin is an oligopeptide with antibiotic and antiviral activity that binds tightly to an adenine-rich sequence of DNA. Atomic resolution x-ray crystal structures of the DNA-netropsin complex have been solved and many experiments have been carried out over the year to understand the thermodynamics …
Wearing Memory Thin: The Effects Of High Fat Diet On Neuroinflammation And Memory, Ashley E.N. Watson, Emily C. Bruggeman, Marise B. Parent
Wearing Memory Thin: The Effects Of High Fat Diet On Neuroinflammation And Memory, Ashley E.N. Watson, Emily C. Bruggeman, Marise B. Parent
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
No abstract provided.
Evaluation Of The Seca Inhibitors As Novel Anti-Microbial Agents, Christina Cerovsky, Jinshan Jin, Hsiuchin Yang, Binghe Wang, Phang C. Tai
Evaluation Of The Seca Inhibitors As Novel Anti-Microbial Agents, Christina Cerovsky, Jinshan Jin, Hsiuchin Yang, Binghe Wang, Phang C. Tai
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
The misuse of conventional antibiotics and natural selection of the infectious bacterial population has produced drug resistance. Thus, novel effective antibiotic compounds that treat bacterial infections resistant to available therapies are needed. SecA is an indispensable ATPase of the protein translocation machinery present in all bacteria. SecA is responsible for the secretion of many essential proteins, some toxins and virulence factors, and is essential for bacterial survival. SecA has no counterpart in mammalian cells, thus provides an ideal target for developing antimicrobial agents. SCA-13 (HO) is a pyrimidine analog derived from virtual screening; it exerts the ability to inhibit SecA …
Time Varying Predictor Model Of Socialization Behavior In Children Diagnosed With Pediatric Brain Tumors, Alyssa Ailion, Tricia King, Christopher Henrich, Robin Morris, Nicholas Krawieck
Time Varying Predictor Model Of Socialization Behavior In Children Diagnosed With Pediatric Brain Tumors, Alyssa Ailion, Tricia King, Christopher Henrich, Robin Morris, Nicholas Krawieck
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Medical advances have improved the survival rate of children with brain tumors, allowing research on long-term outcomes. Prior research suggests that social functioning is often negatively affected by brain insults, and social functioning may be related to childhood receptive vocabulary in children with traumatic brain injuries (Greenham et al., 2010). The current study addressed this hypothesis with children diagnosed with pediatric brain tumors longitudinally using latent growth curve modeling (LGCM). Our sample consisted of 154 children with 544 evaluations from 2 to 7 years post diagnosis. All children completed the Peabody Picture Vocabulary Test Revised (PPVT-R) and Vineland Socialization Scale. …
Social Support, Gender, And Treatment-Seeking Behavior For Substance Abuse: Does Social Support Influence Treatment Attendance Among Substance Abusing Women And Men?, Robyn Borgman, Joanna Akin
Social Support, Gender, And Treatment-Seeking Behavior For Substance Abuse: Does Social Support Influence Treatment Attendance Among Substance Abusing Women And Men?, Robyn Borgman, Joanna Akin
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Women are less likely than men to seek treatment for substance abuse (alcohol and illicit drugs). In 2005, women comprised about 32% of all substance abusers seeking treatment (SAMHSA, 2005). One study found that 23% of men and 15.1% of women with alcohol abuse or dependence had ever received treatment, suggesting that a smaller proportion of substance abusing women receive treatment than substance abusing men (Greenfield et al., 2006). Reduced treatment-seeking among women may be due to an interaction of both external and internal barriers. External barriers are defined as socio-cultural or structural factors discouraging treatment attendance and internal barriers …
Quality Of Relationships And Alcohol Dependence In Young Adults, Darlene Belen, Allie Ramsay
Quality Of Relationships And Alcohol Dependence In Young Adults, Darlene Belen, Allie Ramsay
DISCOVERY: Georgia State Honors College Undergraduate Research Journal
Alcohol dependence and abuse in young adults is a growing problem, especially on college campuses. Relationships between young adults and their family members and peers appear to be factors that influence alcohol use. Previous research on alcohol use and relationships has primarily focused on relationship satisfaction or parent involvement, and few studies have investigated the quality of sibling and friend relationships. The purpose of this study was to examine how different dimensions of relationships (i.e., support, depth, and conflict) and relationship type (i.e., parent, sibling, significant other, and same-sex friend) are related to alcohol dependence in young adults. College students …