Medicine and Health Sciences Commons^™

The Effect Of Different Interfaces On Aerosol Delivery In Simulated Spontaneously Breathing Adult With Tracheostomy, Alaa Ahmed Bugis

Respiratory Therapy Theses

Background: The delivery of an aerosol via a tracheostomy tube has been previously described with both a tracheostomy collar and a T-piece, but not with a Wright mask, or aerosol mask. The primary purpose of this study was to quantify lung doses using different interfaces: tracheostomy collar, Wright mask, and aerosol mask. The secondary purposes were to compare albuterol delivery between an opened vs. a closed fenestration hole and also to determine the effect of inspiratory time:expiratory time (I:E) ratio on aerosol delivery.

Methods: A teaching mannequin (Medical Plastic Labs, Gatesville, TX) with a tracheostomy opening was used. Two of …

Comparison Of Albuterol Delivery Between High Frequency Oscillatory Ventilation And Conventional Mechanical Ventilation In A Simulated Adult Lung Model Using Different Compliance Levels, Waleed A. Alzahrani

Respiratory Therapy Theses

COMPARISON OF ALBUTEROL DELIVERY BETWEEN HIGH FREQUENCY OSCILLATORY VENTILATION AND CONVENTIONAL MECHANICAL VENTILATION IN A SIMULATED ADULT LUNG MODEL USING DIFFERENT COMPLIANCE LEVELS By Waleed A. Alzahrani, BSRT BACKGROUND: Delivery of aerosol by pMDI has been described with conventional mechanical ventilation (CMV) but not with high frequency oscillatory ventilation (HFOV). The purpose of this study was to compare aerosol delivery to a simulated 75 kg adult with low compliance during both CMV and HFOV. Since actuation of pMDI with inspiration is not feasible with HFOV, we investigated the impact of actuation timing only during CMV. METHOD: CMV (Respironics Esprit) and …

Effects Of Heat And Moisture Exchangers Designed To Allow Aerosol Delivery On Airflow Resistance And Aerosol Deposition, William Sonny Bowers Ii

Respiratory Therapy Theses

Introduction: Several problems arise when HMEs are used while giving aerosolized medication including increased airway resistance (Raw) or the need to open the ventilator circuit. Recently, heat and moisture exchangers designed to allow aerosol delivery (HME-AD) have been developed to solve this problem, but no tests have been performed to confirm their effectiveness. The purpose of this study is to evaluate the effect of HME-ADs on aerosol deposition and Raw.

Methods: An in-vitro lung model consisting of an 8.0 mm ID endotracheal tube (ETT) connected to a standard ventilator circuit and ventilator was connected to a rubber test lung via …