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Faculty of Medicine, Menoufia University

Methotrexate

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Association Of Janus Kinase 2 With Primary Budd-Chiari Syndrome In Egyptian Patients, Asmaa M. Rezk, Mohamed A. Mohamed, Mona F. Mahmoud Dec 2014

Association Of Janus Kinase 2 With Primary Budd-Chiari Syndrome In Egyptian Patients, Asmaa M. Rezk, Mohamed A. Mohamed, Mona F. Mahmoud

Menoufia Medical Journal

Objective To investigate the effect of pentoxifylline (PTX) and pioglitazone (Pg), each alone and in combination with methotrexate (MTX), on rheumatoid arthritis (RA) induced experimentally in male albino rats. Background Individuals have long feared RA as one of the most disabling types of arthritis. It is estimated that over 46 million individuals have arthritis, ~1% worldwide. Material and methods One hundred and eighty adult male albino rats were used in the present study. MTX was administered intraperitoneally at a dose of 0.25 mg/kg daily. PTX was administered intraperitoneally at a dose of 150 mg/kg/rat/day, whereas Pg was administered orally at …