Medicine and Health Sciences Commons^™

Possible Role Of Common Spices As A Preventive And Therapeutic Agent For Alzheimer's Disease, Omid Mirmosayyeb, Amirpouya Tanhaei, Hamid R. Sohrabi, Ralph Martins, Mana Tanhaei, Mohammad Admin Najaf, Ali Safaei, Rokhsareh Meamar

Research outputs 2014 to 2021

For centuries, spices have been consumed as food additives or medicinal agents. However, there is increasing evidence indicating the plant-based foods in regular diet may lower the risk of neurodegenerative diseases including Alzheimer disease. Spices, as one of the most commonly used plant-based food additives may provide more than just flavors, but as agents that may prevent or even halt neurodegenerative processes associated with aging. In this article, we review the role and application of five commonly used dietary spices including saffron turmeric, pepper family, zingiber, and cinnamon. Besides suppressing inflammatory pathways, these spices may act as antioxidant and inhibit …

Study Protocol Of The Intense Physical Activity And Cognition Study: The Effect Of High-Intensity Exercise Training On Cognitive Function In Older Adults, Belinda M. Brown, Stephanie Rainey-Smith, Natalie Castalanelli, Nicole Gordon, Shaun Markovic, Hamid R. Sohrabi, Michael Weinborn, Simon Laws, James Doecke, Kaikai Shen, Ralph Martins, Jeremiah J. Peiffer

Research outputs 2014 to 2021

Introduction:

Inconsistent results from previous studies of exercise and cognitive function suggest that rigorously designed randomized controlled trials are urgently needed. Here, we describe the design of the Intense Physical Activity and Cognition (IPAC) study, which will assess the impact of a 6-month high-intensity exercise intervention on cognitive function and biomarkers of dementia risk, compared with a 6-month moderate-intensity exercise intervention and control group (no study-related exercise).

Methods:

One-hundred and five cognitively healthy men and women aged between 60 and 80 years are randomized into a high-intensity exercise, moderate-intensity exercise, or control group. Individuals randomized to an exercise …