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Full-Text Articles in Medicine and Health Sciences
A Surface Based Approach For Cortical Thickness Comparison Between Pib+ And Pib-Healthy Control Subjects, V Dore, P Bourgeat, J Fripp, O Acosta, G Chetelat, C Szoeke, Kathryn Ellis, Ralph Martins, V Villemagne, C L Masters, D Ames, C 0 Rowe, O Salvado
A Surface Based Approach For Cortical Thickness Comparison Between Pib+ And Pib-Healthy Control Subjects, V Dore, P Bourgeat, J Fripp, O Acosta, G Chetelat, C Szoeke, Kathryn Ellis, Ralph Martins, V Villemagne, C L Masters, D Ames, C 0 Rowe, O Salvado
Research outputs 2012
β-amyloid has been shown to play a crucial role in Alzheimer's disease (AD). In vivo β-amyloid imaging using [11C] Pittsburgh compound B (PiB) positron emission tomography has made it possible to analyze the relationship between β-amyloid deposition and different pathological markers involved in AD. PiB allows us to stratify the population between subjects which are likely to have prodromal AD, and those who don't. The comparison of the cortical thickness in these different groups is important to better understanding and detect the first symptoms of the disease which may lead to an earlier therapeutic care to reduce neurone loss. Several …