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A Geospatiotemporal And Causal Inference Epidemiological Exploration Of Substance And Cannabinoid Exposure As Drivers Of Rising Us Pediatric Cancer Rates, Albert S. Reece, Gary K. Hulse
A Geospatiotemporal And Causal Inference Epidemiological Exploration Of Substance And Cannabinoid Exposure As Drivers Of Rising Us Pediatric Cancer Rates, Albert S. Reece, Gary K. Hulse
Research outputs 2014 to 2021
Background: Age-adjusted US total pediatric cancer incidence rates (TPCIR) rose 49% 1975–2015 for unknown reasons. Prenatal cannabis exposure has been linked with several pediatric cancers which together comprise the majority of pediatric cancer types. We investigated whether cannabis use was related spatiotemporally and causally to TPCIR. Methods: State-based age-adjusted TPCIR data was taken from the CDC Surveillance, Epidemiology and End Results cancer database 2003–2017. Drug exposure was taken from the nationally-representative National Survey of Drug Use and Health, response rate 74.1%. Drugs included were: tobacco, alcohol, cannabis, opioid analgesics and cocaine. This was supplemented by cannabinoid concentration data from the …