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Ensuring A Knowledgeable Geriatric Workforce: Interdisciplinary Education In Long-Term Services And Supports, Gina Tucker-Roghi Dec 2022

Ensuring A Knowledgeable Geriatric Workforce: Interdisciplinary Education In Long-Term Services And Supports, Gina Tucker-Roghi

Occupational Therapy | Faculty Scholarship

In this symposium, we describe five interdisciplinary educational programs to enhance the geriatric workforce in long-term services and supports (LTSS): Skilled nursing facilities (SNFs), assisted living, and home health and hospice. The interdisciplinary teams that came together to offer the programs leveraged technology to maximize access to experts in both the curriculum development process and the delivery of the educational programs for a wide range of target learners. The first program, an interdisciplinary telementoring series on dementia care for therapists in SNFs, was developed by a team of experts from occupational, physical and speech therapy. The program included asynchronous online …


Interdisciplinary Telementoring For Therapists In Snfs To Improve Dementia Care Knowledge And Skills, Gina Tucker-Roghi Dec 2022

Interdisciplinary Telementoring For Therapists In Snfs To Improve Dementia Care Knowledge And Skills, Gina Tucker-Roghi

Occupational Therapy | Faculty Scholarship

Occupational, physical, and speech therapists possess knowledge and skills that have the potential to reduce the burden of care and improve the quality of life of skilled nursing facility (SNF) residents living with dementia. Despite this opportunity to impact the well-being of residents with dementia, many therapy practitioners lack specialized training on the management of dementia. Therapy practitioners (n=31) from 22 SNFs participated in eight weekly interdisciplinary educational sessions using the Project ECHO (Extension for Community Health Outcomes) tele-mentoring model. An interdisciplinary team of therapy experts collaborated on the development of the curriculum, which included didactic content on dementia-care best …


Education Research: Neurologic Education In Physician Assistant Programs, Carl Garubba Dec 2022

Education Research: Neurologic Education In Physician Assistant Programs, Carl Garubba

Physician Assistant Studies | Faculty Scholarship

Background and Objectives A growing number of advanced practice providers (APPs) are entering neurologic practice, and educational initiatives focused on postgraduate training in neurology for these providers are growing in turn. Neurologic education in APP degree programs is not well defined, which limits the ability to tailor these initiatives to the specific needs of APPs. We aim to describe neurologic education in physician assistant (PA) degree programs to better inform these efforts.

Methods The 2018 American Academy of Neurology clerkship director survey was adapted for directors of PA programs via an iterative approach. The survey was distributed to program directors …


Systematic Review Brief: Virtual Interventions That Address Motor And Balance Impairments And Skills For Adults With Traumatic Brain Injury (Tbi) (12-21), Kitsum Li, Beth Fields, Adam Kinney, Olivia Condon, Emilio Villavicencio Sep 2022

Systematic Review Brief: Virtual Interventions That Address Motor And Balance Impairments And Skills For Adults With Traumatic Brain Injury (Tbi) (12-21), Kitsum Li, Beth Fields, Adam Kinney, Olivia Condon, Emilio Villavicencio

Occupational Therapy | Faculty Scholarship

Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association’s (AOTA’s) Evidence-Based Practice Program. Each Systematic Review Brief summarizes the evidence on a theme related to a systematic review topic. This Systematic Review Brief presents findings from the theme of virtual interventions that address motor and balance impairments and skills for adults with traumatic brain injury (TBI).


Physical Activity Interventions That Address Motor And Balance Impairments And Skills For Adults With Traumatic Brain Injury (Tbi) (2012-2021), Beth Fields, Kitsum Li, Adam Kinney, Olivia Condon, Emilio Villavicencio Sep 2022

Physical Activity Interventions That Address Motor And Balance Impairments And Skills For Adults With Traumatic Brain Injury (Tbi) (2012-2021), Beth Fields, Kitsum Li, Adam Kinney, Olivia Condon, Emilio Villavicencio

Occupational Therapy | Faculty Scholarship

Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association’s (AOTA’s) Evidence-Based Practice Program. Each Systematic Review Brief summarizes the evidence on a theme related to a systematic review topic. The systematic review is on interventions to address motor and balance impairments to improve occupational performance for adults with TBI, the theme reported in this Systematic Review Brief is physical activity interventions.


Batok: The Exploration Of Indigenous Filipino Tattooing As A Resistive Collective Occupation, Chelsea Ramirez, Karen Mccarthy, Ana Cabalquinto, Carmela Dizon, Mai Santiago Aug 2022

Batok: The Exploration Of Indigenous Filipino Tattooing As A Resistive Collective Occupation, Chelsea Ramirez, Karen Mccarthy, Ana Cabalquinto, Carmela Dizon, Mai Santiago

Occupational Therapy | Faculty Scholarship

Batok (also known as Fatek/Burik/Tatak/Batek/Patik) is an Indigenous Filipino tattooing practice where the practitioner marks the skin by hand-tapping the ink using bone/wood implements. Previous research on tattooing from an occupational science perspective has considered European tattooing and its engagement and implication on the individual. This qualitative research explores how batok is experienced by the person and their identified community. Three Filipino participants with batok, and four family or community members were interviewed. Thematic analysis highlighted three themes recognized as Kapwa, Revealing One’s Batok, and Decolonization and Reclamation as a Cultural Practice. These themes are situated in the lens of …


Exploring The Meaningful Qualities Of Transactions In Virtual Environments For Massively Multiplayer Online Role-Playing Gamers, Karen Mccarthy, Shasta Rice, Amanda Flores, John Miklos, Alex Nold Aug 2022

Exploring The Meaningful Qualities Of Transactions In Virtual Environments For Massively Multiplayer Online Role-Playing Gamers, Karen Mccarthy, Shasta Rice, Amanda Flores, John Miklos, Alex Nold

Occupational Therapy | Faculty Scholarship

To date, most research on massively multiplayer online role-playing games (MMORPGs) has focused on the effects playing MMORPGs have on players’ health and wellness. The virtual environment of MMORPGs has yet to be explored as a space where meaningful occupations occur. This qualitative descriptive study examined the virtual environment using a transactional perspective to describe the qualities of gaming to which MMORPG players ascribe meaning. Participants included six MMORPG players with experience playing World of Warcraft, Runescape, or Guild Wars 2. Data were gathered using interviews, participant observation, and a focus group, and analyzed using thematic analysis. Three themes were …


Exploring Dating As An Occupation For Young Heterosexual Women In Ireland, Karen Mccarthy, Jeanne Jackson Jul 2022

Exploring Dating As An Occupation For Young Heterosexual Women In Ireland, Karen Mccarthy, Jeanne Jackson

Occupational Therapy | Faculty Scholarship

Purpose – Dating is a meaningful occupation for many single people. The occupation of dating has transformed considerably in Ireland due to recent changes in Irish culture and the advent of online dating technology. The purpose of this study was to explore the complexities and intricacies of dating in an Irish context.

Design/methodology/approach – A qualitative research approach was used and data were collected using semi-structured interviews with ten heterosexual women (age 24-34) living in urban areas of Ireland. Data were analysed using inductive thematic analysis (Braun and Clarke, 2006).

Findings – Dating did not fully resonate with their experience, …


Global Developments In Social Prescribing, Daniel F. Morse, Sahil Sandhu, Kate Mulligan, Stephanie Tierney, Marie Polley, Bogdan Chiva Giurca, Siân Slade, Sónia Dias, Kamal R. Mahtani, Leanne Wells, Huali Wang, Bo Zhao, Cristiano Emanuel Marta De Figueiredo, Jan Joost Meijs, Hae Kweun Nam, Kheng Hock Lee, Carolyn Wallace, Megan Eliott, Juan Manuel Mendive, David Robinson, Miia Palo, Wolfram Hermann, Rasmus Østergaard Nielsen, Kerryn Husk May 2022

Global Developments In Social Prescribing, Daniel F. Morse, Sahil Sandhu, Kate Mulligan, Stephanie Tierney, Marie Polley, Bogdan Chiva Giurca, Siân Slade, Sónia Dias, Kamal R. Mahtani, Leanne Wells, Huali Wang, Bo Zhao, Cristiano Emanuel Marta De Figueiredo, Jan Joost Meijs, Hae Kweun Nam, Kheng Hock Lee, Carolyn Wallace, Megan Eliott, Juan Manuel Mendive, David Robinson, Miia Palo, Wolfram Hermann, Rasmus Østergaard Nielsen, Kerryn Husk

Applied Computer Science | Faculty Scholarship

Social prescribing is an approach that aims to improve health and well-being. It connects individuals to non-clinical services and supports that address social needs, such as those related to loneliness, housing instability and mental health. At the person level, social prescribing can give individuals the knowledge, skills, motivation and confidence to manage their own health and well-being. At the society level, it can facilitate greater collaboration across health, social, and community sectors to promote integrated care and move beyond the traditional biomedical model of health. While the term social prescribing was first popularised in the UK, this practice has become …


Preclinical Characterization And Target Validation Of The Antimalarial Pantothenamide Mmv693183., Laura E. De Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M J Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering Apr 2022

Preclinical Characterization And Target Validation Of The Antimalarial Pantothenamide Mmv693183., Laura E. De Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M J Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering

Natural Sciences and Mathematics | Faculty Scholarship

Drug resistance and a dire lack of transmission-blocking antimalarials hamper malaria elimination. Here, we present the pantothenamide MMV693183 as a first-in-class acetyl-CoA synthetase (AcAS) inhibitor to enter preclinical development. Our studies demonstrate attractive drug-like properties and in vivo efficacy in a humanized mouse model of Plasmodium falciparum infection. The compound shows single digit nanomolar in vitro activity against P. falciparum and P. vivax clinical isolates, and potently blocks P. falciparum transmission to Anopheles mosquitoes. Genetic and biochemical studies identify AcAS as the target of the MMV693183-derived antimetabolite, CoA-MMV693183. Pharmacokinetic-pharmacodynamic modelling predict that a single 30 mg oral dose is sufficient …


Discovery And Preclinical Pharmacology Of Ine963, A Potent And Fast-Acting Blood-Stage Antimalarial With A High Barrier To Resistance And Potential For Single-Dose Cures In Uncomplicated Malaria., Benjamin R. Taft, Fumiaki Yokokawa, Tom Kirrane, Anne-Catherine Mata, Richard Huang, Nicole Blaquiere, Grace Waldron, Bin Zou, Oliver Simon, Subramanyam Vankadara, Wai Ling Chan, Mei Ding, Sandra Sim, Judith Straimer, Armand Guiguemde, Suresh B Lakshminarayana, Jay Prakash Jain, Christopher Bodenreider, Christopher Thompson, Christian Lanshoeft, Wei Shu, Eric Fang, Jafri Qumber, Katherine Chan, Luying Pei, Yen-Liang Chen, Hanna Schulz, Jessie Lim, Siti Nurdiana Abas, Xiaoman Ang, Yugang Liu, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Glaxosmithkline Gamo, Benigno Crespo-Fernandez, Philip J. Rosenthal, Roland A. Cooper, Patrick Tumwebaze, Anna Caroline Campos Aguiar, Brice Campo, Simon Campbell, Jürgen Wagner, Thierry T Diagana, Christopher Sarko Mar 2022

Discovery And Preclinical Pharmacology Of Ine963, A Potent And Fast-Acting Blood-Stage Antimalarial With A High Barrier To Resistance And Potential For Single-Dose Cures In Uncomplicated Malaria., Benjamin R. Taft, Fumiaki Yokokawa, Tom Kirrane, Anne-Catherine Mata, Richard Huang, Nicole Blaquiere, Grace Waldron, Bin Zou, Oliver Simon, Subramanyam Vankadara, Wai Ling Chan, Mei Ding, Sandra Sim, Judith Straimer, Armand Guiguemde, Suresh B Lakshminarayana, Jay Prakash Jain, Christopher Bodenreider, Christopher Thompson, Christian Lanshoeft, Wei Shu, Eric Fang, Jafri Qumber, Katherine Chan, Luying Pei, Yen-Liang Chen, Hanna Schulz, Jessie Lim, Siti Nurdiana Abas, Xiaoman Ang, Yugang Liu, Iñigo Angulo-Barturen, María Belén Jiménez-Díaz, Glaxosmithkline Gamo, Benigno Crespo-Fernandez, Philip J. Rosenthal, Roland A. Cooper, Patrick Tumwebaze, Anna Caroline Campos Aguiar, Brice Campo, Simon Campbell, Jürgen Wagner, Thierry T Diagana, Christopher Sarko

Natural Sciences and Mathematics | Faculty Scholarship

A series of 5-aryl-2-amino-imidazothiadiazole (ITD) derivatives were identified by a phenotype-based high-throughput screening using a blood stage Plasmodium falciparum (Pf) growth inhibition assay. A lead optimization program focused on improving antiplasmodium potency, selectivity against human kinases, and absorption, distribution, metabolism, excretion, and toxicity properties and extended pharmacological profiles culminated in the identification of INE963 (1), which demonstrates potent cellular activity against Pf 3D7 (EC50 = 0.006 μM) and achieves "artemisinin-like" kill kinetics in vitro with a parasite clearance time of/kg is fully curative in the Pf-humanized severe combined immunodeficient mouse model. INE963 (1) also exhibits a high barrier to resistance …


Bits & Pieces: Project Review, Erin Partridge, Sadie Harmon, Katie Wade, Casey O'Neill Jan 2022

Bits & Pieces: Project Review, Erin Partridge, Sadie Harmon, Katie Wade, Casey O'Neill

Art Therapy | Project Reports

This project explores the impact of creative collaboration on social connections between participants and volunteers in a friendly visiting program to answer the following questions:

  1. What is the significance of a participatory based research process where older adults, staff, and volunteers are all primary contributors?

  2. How can we co-design programming to elevate a sense of meaning and connection for staff, participants, and volunteers?


Interprofessional Collaboration In High Performing Healthcare Teams, Zilola Khashimova Jan 2022

Interprofessional Collaboration In High Performing Healthcare Teams, Zilola Khashimova

Physician Assistant Studies | Faculty Scholarship

As healthcare becomes more complicated, it is important for healthcare workers to collaborate and work together as a team to provide high quality healthcare to patients. Interprofessional teams have been widely introduced into healthcare organizations across the nation aimed at achieving patient centered care and increasing the quality of patient care. The introduction of technology like electronic medical records, escribing, telehealth, and telemedicine gave interprofessional collaborators alternative mediums for communication to achieve patient centered care rather than traditional communication mediums. Technology has evolved the way interprofessional collaboration is done in the healthcare field and has created barriers and solutions for …


Providing Healthcare Workers In Medically Underserved Areas: A Case Study, Zilola Khashimova Jan 2022

Providing Healthcare Workers In Medically Underserved Areas: A Case Study, Zilola Khashimova

Physician Assistant Studies | Faculty Scholarship

Introduction: Demographic trends forecast an increasing population of aging, chronically ill patents in rural areas of the Southeastern United States. Most healthcare professionals opt to practice in or near urban areas because of higher incomes and nearness to desirable facilities. This leaves a chronic shortage of healthcare providers in rural areas where they are critically needed. A university located in one of the critically underserved areas started a program to train physician assistants with the idea that most of the students would be residents of the area and tend to stay in the area to practice after graduation.
Purpose of …