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Systematic Review Comparing All-Cause Mortality Rates Between Tavr And Savr To Treat High Risk Surgical Patients With Severe Aortic Stenosis, Emily Belz
Physician Assistant Studies | Student Articles
Background: Our goal was to conduct a systematic review of available randomized controlled trials to compare the safety and efficacy of TAVR to SAVR by looking at absolute risk reduction in all-cause mortality for high risk surgical patients with severe aortic stenosis at 1, 2 and 5 years post-intervention.
Methods/Results: The PubMed database was searched according to the PRISMA guidelines from inception until September 2020. 6 high quality randomized controlled trials analyzing all-cause mortality for TAVR versus SAVR in the CoreValve US High-Risk Clinical Study and Placement of Aortic Transcatheter Valves (PARTNER) Trial populations at 1, 2 and 5 years …