Medicine and Health Sciences Commons^™

A Critical Hermeneutic Analysis Of Presence In Nursing Practice, Alicia L. Bright

Collected Faculty and Staff Scholarship

Nursing presence, although it involves action at times, is a humanitarian quality of relating to a patient that is known to have powerful and positive implications for both nurse and patient. However, this phenomenon has not been well understood. Three theories, drawn from the work of Paul Ricoeur and Hans-Georg Gadamer, served as the boundaries for both data collection and analysis. The theories were narrative identity, play and solicitude. This study follows a critical hermeneutic approach to field research and data analysis. Literature regarding nursing presence is reviewed and discussed, and in-depth conversations with eleven participants are recorded. Examining the …

Lack Of Resistance Of Plasmodium Falciparum To Dihydroartemisinin In Uganda Based On Parasitogolgical And Molecular Assays, Roland A. Cooper, Melissa D. Conrad, Quentin D. Watson, Stephanie J. Huezo, Harriet Ninsiima, Patrick Tumwebaze, Samuel L. Nsobya, Philip J. Rosenthal

Collected Faculty and Staff Scholarship

• Artemisinin-­‐based combination therapy is now standard treatment for falciparum malaria. However, this regimen is threatened by resistance to artemisinins, manifest as delayed clearance of parasitemia after therapy, in southeast Asia.

• Artemisinin resistance in southeast Asia is associated with increased parasitemias in culture, compared to those in sensi0ve parasites, 72 hours a=er a 6 hour pulse with 700 nM dihydroartemisinin (DHA), and with propeller domain polymorphisms in the Plasmodium falciparum kelch (K13; PF3D7_1343700) gene

• Given that artemether/lumefantrine has been adopted as standard therapy for malaria within the last decade in Uganda, we characterized artemisinin sensiBvity in fresh P. falciparum isolates from …

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Mild Cognitive Impairment In Heart Failure Affects Care Transition, Kitsum Li, Kristin Myers

Collected Faculty and Staff Scholarship

Objectives

After attending the presentation, the audiences will be able to:

• Understand the importance of cognition in everyday activity and the cognitive hierarchy to guide practice.
• Recognize the incidence of mild cognitive impairment in individuals with heart failure.
• Understand how mild cognitive impairment may affect heart failure self- care practice and hospitalization readmission.
• Identify the evidence that support use of cognitive screen to identify mild cognitive impairment in individuals with heart failure.
• Compare the evidence among three cognitive screens (Mini-mental Status Exam, Montreal Cognitive Assessment and St. Louis University Mental State Exam).
• (Using Montreal Cognitive Assessment as an example)Identify cognitive …

Exercise: An Antecedent Based Intervention To Address Sensory Motor Needs And Learning Readiness, Laura Greiss Hess, Heather Maurin

Collected Faculty and Staff Scholarship

• “Exercise (ECE) is a strategy that involves an increase in physical exertion as a means of reducing problem behaviors or increasing appropriate behavior while increasing physical fitness and motor skills”
• “ECE can be used effectively to address behavior, school-readiness, academic, and motor skills.” NPDC Exercise Fact Sheet, 2014

Effects Of Sertraline Treatment For Young Children With Fxs, Andrew Ligsay, Laura Greiss Hess, Sarah Fitzpatrick, Kerrie Lemons Chitwood, Jonathan Polussa, Salpi Siyahian, Randi Hagerman

Collected Faculty and Staff Scholarship

Selective serotonin reuptake inhibitors (SSRIs) help treat many of the phenotypic manifestations of fragile X syndrome (FXS) including anxiety, sensory processing challenges, and communication and intellectual deficits. However, the efficacy of SSRIs has not been previously studied in children with FXS under five-years-old. The purpose of this study was to elucidate group differences in behavior and developmental outcome measures for young children with FXS when treated with sertraline compared to placebo.

Mutations In The Plasmodium Falciparum Chloroquine Resistance Transporter, Pfcrt, Enlarge The Parasite's Food Vacuole And Alter Drug Sensitivities, Serena Pulcini, Henry M. Staines, Andrew H. Lee, Sarah H. Shafik, Guillaume Bouyer, Catherine M. Moore, Daniel A. Daley, Matthew J. Hoke, Lindsey M. Altenhofen, Heather J. Painter, Jianbing Mu, David J. P. Ferguson, Manuel Llinas, Rowen E. Martin, David A. Fidock, Roland Cooper, Sanjeev Krishna

Collected Faculty and Staff Scholarship

Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we describe P. falciparum lines subjected to selection by amantadine or blasticidin that carry PfCRT mutations (C101F or L272F), causing the development of enlarged food vacuoles. These parasites also have increased sensitivity to chloroquine and some other quinoline antimalarials, but exhibit no or minimal change in sensitivity to artemisinins, when compared with parental strains. A transgenic parasite line expressing the L272F variant of PfCRT confirmed this increased chloroquine sensitivity and enlarged food vacuole phenotype. Furthermore, the introduction …

A Comparison Of Skills Competency Test Scores Among Philippine-Educated Nursing Students After An Intensive Medical-Surgical Course, Margaret Fink, Debbie Daunt, Patricia Harris, Barbara Mccamish

Collected Faculty and Staff Scholarship

Objective: This study examined the effect of a 10-week intensive medical-surgical course on ability to perform 16 common, acute care skills among Philippine educated nursing students seeking licensure in California. The aims of the study were to (1) determine competency in performing skills at the start of the medical-surgical course and (2) evaluate the effectiveness of the medical-surgical course in improving skill competency.

Methods: Twenty-three Philippine educated nursing students participated in a 4-hour skills competency test procedure that involved 4 patient care stations and 16 common acute care skills. During the last week of the 10-week medical-surgical course that included …

Lack Of Artemisinin Resistance In Plasmodium Falciparum In Uganda Based On Parasitological And Molecular Assays, Roland A. Cooper, Melissa D. Conrad, Quentin D. Watson, Stephanie J. Huezo, Harriet Ninsiima, Patrick Tumwebaze, Samuel L. Nsobya, Philip J. Rosenthal

Collected Faculty and Staff Scholarship

We evaluated markers of artemisinin resistance in Plasmodium falciparum isolated in Kampala in 2014. By standard in vitro assays, all isolates were highly sensitive to dihydroartemisinin (DHA). By the ring-stage survival assay, after a 6-h DHA pulse, parasitemia was undetectable in 40 of 43 cultures at 72 h. Two of 53 isolates had nonsynonymous K13-propeller gene polymorphisms but did not have the mutations associated with resistance in Asia. Thus, we did not see evidence for artemisinin resistance in Uganda.

Does Generalization Occur Following Computer-Based Cognitive Retraining?—An Exploratory Study, Kitsum Li, Jonathan Alonso, Nisha Chadha, Jennifer Pulido

Collected Faculty and Staff Scholarship

Computer-based cognitive retraining (CBCR) intervention has gained great popularity in recent years. This study aimed to investigate the occurrence of skill generalization to daily living task for individuals with acquired brain injury (ABI) after completion of eight modules of a commercially available CBCR program, the Parrot Software. The study investigated changes in individuals’ global cognition as measured by the Montreal Cognitive Assessment, and changes in individuals’ performance during a medication-box sorting task, a novel instrumental activity of daily living. The medication-box sorting task resembled real life medication management with daily prescribed and over-the-counter medications. Twelve individuals with ABI from a …

Impact Of Antimalarial Treatment And Chemoprevention On The Drug Sensitivity Of Malaria Parasites Isolated From Ugandan Children, Patrick Tumwebaze, Melissa D. Conrad, Andrew Walakira, Norbert Leclair, Oswald Byaruhanga, Christine Nakazibwe, Benjamin Kozak, Jessica Bloome, Jaffer Okiring, Abel Kakuru, Victor Bigira, James Kapisi, Jennifer Legac, Jiri Gut, Roland A. Cooper, Moses R. Kamya, Diane V. Havlir, Grant Dorsey, Bryan Greenhouse, Samuel L. Nsobya, Philip J. Rosenthal

Collected Faculty and Staff Scholarship

Changing treatment practices may be selecting for changes in the drug sensitivity of malaria parasites. We characterized ex vivo drug sensitivity and parasite polymorphisms associated with sensitivity in 459 Plasmodium falciparum samples obtained from subjects enrolled in two clinical trials in Tororo, Uganda, from 2010 to 2013. Sensitivities to chloroquine and monodesethylamodiaquine varied widely; sensitivities to quinine, dihydroartemisinin, lumefantrine, and piperaquine were generally good. Associations between ex vivo drug sensitivity and parasite polymorphisms included decreased chloroquine and monodesethylamodiaquine sensitivity and increased lumefantrine and piperaquine sensitivity with pfcrt 76T, as well as increased lumefantrine sensitivity with pfmdr1 86Y, Y184, and 1246Y. …

Ot On College Campuses: Emerging Models Faciltitating Student Success Through Occupation, Lisa Crabtree, Carlin Daley, Jeanne Eichler, Karen Mccarthy, Victoria Schindler

Collected Faculty and Staff Scholarship

No abstract available

Does Therapeutic Horseback Riding Decrease Balance Deficits In Community-Dwelling Older Adults?, Salwa Yaser, Lisa Mrsny, Krystin Beeman, Skyler Moon, Kitsum Li

Occupational Therapy | Critically Appraised Papers Series

Hippotherapy and therapeutic riding (TR) provide pleasurable activity and physical exercise to individuals and yet limited study is available on its therapeutic value to improve balance in older adults. In this study, the researchers measured the benefit of TR on balance and quality of life in communitydwelling older adults. A convenience sample of individuals 65 years and older was recruited from a local community. The study is a single-blind, pretest-posttest, controlled study of a 10-session TR program with a Professional Association of Therapeutic Horsemanship (PATH) trained and certified TR instructor. Each TR session included grooming and tacking, mounting, a warm-up …

Does A Multicomponent Home Intervention Reduce Functional Difficulties In Community-Dwelling Older Adults As Compared To No Intervention?, Laura Henty-Clark, Rosemarie Lion, Nadine Marcelo, Kitsum Li

Occupational Therapy | Critically Appraised Papers Series

Many older adults live with chronic conditions that may affect their ability to safely perform their daily occupations. Small decreases in ability of older adults to function independently can have profound effects, possibly leading to hospitalization, institutionalization, or death. However, preventative home-based interventions for older adults typically are not reimbursed by Medicare or other insurance carriers.

This study on intervention effectiveness contributes to a growing body of evidence for providing preventative home-based intervention to older adults to support their abilities to function independently in their communities. This study examined whether a preventative home-based intervention, including occupational therapy and physical therapy, …

For Low-Income Adults Who Experience Trouble With One Or More Activities Of Daily Living (Adl) Or Two Or More Instrumental Activities Of Daily Living (Iadl), Does The Community Aging In Place: Advancing Better Living For Elders (Capable) Improve Performance Of Adls And Iadls?, Noelle Bakken, Lauryn Banovitz, Abigail Lafrenz, Kitsum Li

Occupational Therapy | Critically Appraised Papers Series

The growing population of older adults has created a societal shift, with many older adults preferring to stay in their homes for a longer period of time. This trend, known as aging-inplace, may provide greater independence and autonomy to older adults compared with those living in nursing homes. However, physical and cognitive changes associated with age may affect the ability to safely perform activities of daily living (ADL) and instrumental activities of daily living (IADL). This study examined performance in ADLs and IADLs, fall efficacy, and quality of life in 40 low-income, community dwelling adults aged 65 and older. Participants …

For Healthy Older Adults, Does Participation In A Water-Based Balance Training Exercise Program, When Compared To A Land-Based Balance Training Exercise Program, Improve Balance Performance?, Sara Pro, Rajvinder Bains, Kitsum Li

Occupational Therapy | Critically Appraised Papers Series

Occupational therapy plays a significant role in wellness promotion for older adults. Critical to maintaining health and wellness in older adults is prevention of falls and fall-related injuries. One in three community-dwelling older adults reports a fall every year, and the incidence of falls increases exponentially from ages 60 to 65 and 80 to 85. Falls are associated with increased morbidity and mortality from fractures and secondary complications. Leading causes of falls in older adults include decreased balance and an abnormal gait pattern. Balance training programs can help improve balance, decrease the risk of falling, and promote functional independence. However, …

Perceptions Of Physician Assistant Students ’ Readiness With System-Based Vs. Problem-Based Physical Diagnosis Curriculum, Carl Garrubba, Kelly Donkers, Laura Daniel, Carol Ennulat

Physician Assistant Studies | Faculty Scholarship

Purpose: The purpose of this study was to identify students’ perceptions of the curriculum in two different cohorts who received two different delivery styles (system-based or problem-based) of physical diagnosis curriculum to determine if significant differences were present, and to identify how each cohort performed on their clinical experiences (CEs). Methods: One-hundred and sixteen students at one physician assistant (PA) program from two cohorts of students were surveyed using a true/false survey (analyzed by chi-square) regarding their perceptions of their preparedness for clinical rotations with regard to the ability to perform physical examinations. Clinical preceptor evaluations were also analyzed for …

Do Restorative Home Care Programs Increase Independence In Adls And Iadls In Older Adults Receiving Home Health Services?, Adrienne Angeles, Shanee Ben-Haim, Amy Smith-Schwartz, Kitsum Li

Occupational Therapy | Critically Appraised Papers Series

There has been a worldwide shift from viewing aging as a dependent stage of life to one that increasingly encourages independence and a more active lifestyle for older adults. In Australia, where this study was conducted, restorative care that embraces active aging was not yet considered an essential component of home health care on the national level. However, restorative home care has been gaining more recognition as increasing importance is placed on independence and self-management in older adults.

The researchers of this study explored whether older adults’ participation in restorative home care programs reduced the need for ongoing personal care. …