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Full-Text Articles in Medicine and Health Sciences

Transition In The Era Of A Pandemic: An Exercise In Mindfulness, Ana Fonseca Conboy Aug 2022

Transition In The Era Of A Pandemic: An Exercise In Mindfulness, Ana Fonseca Conboy

Languages and Cultures Faculty Publications

COVID-19 took over the world in March 2020 and overturned our practices, customs, and perspectives. It reminded us that how we relate to one another defines how we choose to build our community and our society. In our forced isolation and confinement, it became evident that we must remember to let go, slow down, and rely on each other to positively influence our future. In times of drastic change, exercising kindness to yourself and to those around you can help wade through challenges and make the best of them, one day at a time, one step at a time. This …


Stirring Up The Soil: Best Practices To Mitigate Lead Exposure In Contaminated Soils Within Omaha, Nebraska, Mckenzie Blaine May 2022

Stirring Up The Soil: Best Practices To Mitigate Lead Exposure In Contaminated Soils Within Omaha, Nebraska, Mckenzie Blaine

Celebrating Scholarship and Creativity Day (2018-)

Cities across the nation in the United States experience problems associated with lead contamination in their urban soils due to industrial pollution. In many instances, the emission of lead particles occurred – unregulated – for several decades. Though there are federal cleanup efforts to help minimize the negative impacts of lead contamination for the public in the United States, the efforts are designated for specified criteria and thus do not reach all areas which need to be remediated. In order to perform proper lead abatement practices, local organizations must take initiative on projects which meet the needs and demands of …


Implementation Of Staff Training Curriculum Aimed At Improving Mds Coding In A Long-Term Care Setting, Maureen Burns, Emalee Driemeyer, Caitlin O'Toole, Eliana Scheett, Erin Sticha Apr 2022

Implementation Of Staff Training Curriculum Aimed At Improving Mds Coding In A Long-Term Care Setting, Maureen Burns, Emalee Driemeyer, Caitlin O'Toole, Eliana Scheett, Erin Sticha

Celebrating Scholarship and Creativity Day (2018-)

Minimum Data Set (MDS) is used in long-term care facilities to document resident’s information and assessments and to determine the resident’s eligibility to receive Medicare or Medicaid insurance coverage for treatment expenses while in the LTC facility. When reviewing the MDS, the facility identified inaccurate documentation of the resident’s functional mobility ambulating on the unit. This quality improvement project was undertaken to improve assessments, resident interventions, and documentation regarding functional mobility. Following literature review and chart audits, an educational intervention was implemented for nursing assistants to promote understanding of the MDS coding system when charting functional mobility on the unit. …


The Development Of Inhibitors For Sars-Cov-2 Orf8, My Thanh Thao Nguyen Apr 2022

The Development Of Inhibitors For Sars-Cov-2 Orf8, My Thanh Thao Nguyen

CSB and SJU Distinguished Thesis

An unexpected outbreak of SARS-CoV-2 caused a worldwide pandemic in 2020. Many repurposed drugs were tested, but there are currently only three FDA approved antivirals (Merck’s antiviral Molnupiravir, Pfizer’s antiviral Paxlovid, and Remdisivir).1 Most of the antiviral drugs tested SARS-CoV-2 main protease and RNA-dependent RNA polymerase. However, it is important to explore different drug targets of SARS-CoV-2 to prepare for the virus mutations of the future. This research looks at an alternative approach in which SARSCoV- 2 Open Reading Frame 8 (ORF8), which has been shown to be a rapidly evolving hypervariable gene, was chosen to be the protein of …


Sars-Cov-2 Main Protease Inhibitors Repurposed For Hiv-1 Protease Binding, Jacob Minkkinen Apr 2022

Sars-Cov-2 Main Protease Inhibitors Repurposed For Hiv-1 Protease Binding, Jacob Minkkinen

CSB and SJU Distinguished Thesis

Severe acute respiratory syndrome (SARS-CoV-2) led to the COVID-19 global pandemic, with over 460 million cases of infection and over 6 million deaths since the start of the pandemic. SARS-CoV-2 is a retrovirus that utilizes a main protease (Mpro). Mpro is a catalytic cys/his protease. Several treatments were proposed to stop the pandemic including repurposing drugs to inhibit the Mpro. Another retrovirus that uses a protease is human immunodeficiency virus (HIV-1) which has been a global epidemic for 40 years and is a devastating disease that attacks the immune system. HIV-1 has infected 79.5 million people and has killed an …