Medicine and Health Sciences Commons^™

The Never-Ending Lap, Ennica D. Jacob, Alexis Reese

Capstones

This personal film documents the journey of a Haitian-American woman dealing with sexual trauma in a culture that doesn’t speak candidly on the topic. How can women of the African- American diaspora break the cycle of sexual trauma and what are coping mechanisms to navigate their life choices with awareness?

The Never-Ending Lap will follow Ennica’s own healing process, delving delve into the cycles of sexual trauma. The film will explore past experiences through journal entries, therapy sessions and her love for track and field as she is on the road to search for coping mechanisms and healing.

Link: https://ennicajacob.myportfolio.com/videos

African American Male Veterans’ Illness Representation And Reported Self-Management Practices Of High Blood Pressure, Tammie Brodie

Dissertations, Theses, and Capstone Projects

High blood pressure (HBP) is a common condition in the United States, affecting one in four American adults. Forty-one percent of African Americans have HBP compared to 27% of White Americans. African Americans develop high blood pressure at an earlier age and suffer more complications compared to other ethnic groups. Numerous studies have been conducted to find the causes and treatment for HBP in African Americans.

The purpose of this research is to explore self-management practices of African-American male veterans, who have positive HBP representation and controlled HBP. A mixed-methods approach guided the study to gain quantitative and qualitative explanatory …

Hot Spot Mutation In Tp53 (R248q) Causes Oncogenic Gain-Of-Function Phenotypes In A Breast Cancer Cell Line Derived From An African American Patient, Nataly Shtraizent, Hiroshi Matsui, Alla Polotskaia, Jill Bargonetti

Publications and Research

African American (AA) breast cancer patients often have triple negative breast cancer (TNBC) that contains mutations in the TP53 gene. The point mutations at amino acid residues R273 and R248 both result in oncogenic gain-of-function (GOF) phenotypes. Expression of mutant p53 (mtp53) R273H associates with increased cell elasticity, survival under serum deprivation conditions, and increased Poly (ADP ribose) polymerase 1 (PARP1) on the chromatin in the AA-derived TNBC breast cancer cell line MDA-MB-468. We hypothesized that GOF mtp53 R248Q expression could stimulate a similar phenotype in the AA-derived TNBC cell line HCC70. To test this hypothesis we depleted the R248Q …

No Rush To Motherhood: The Lived Experience Of African American Never Pregnant Sexually Active Female Teens, Monique Jenkins

Dissertations, Theses, and Capstone Projects

The purpose of this study was to explore the experiences of sexually active never pregnant African American female adolescents living in an underserved neighborhood including discussions on their thoughts about ways other teens can similarly avoid pregnancy. The study was conducted using a Hermeneutic phenomenological qualitative approach as described and outlined by Merleau-Ponty as well as the van Manen technique to analyze data obtained in this study. This study contributes to the nursing literature and was conducted to understand the essence and meaning of pregnancy avoidance as experienced by sexually active, never pregnant African American female teens within the context …