Medicine and Health Sciences Commons^™

A Review Of Consanguinity In The Iraqi Population: A Call To Action To Prevent A Future Health Catastrophe, Zaid Ali Hawi, Kealan Pugsley, Atefeh Namipashaki, Walied Samarrai, Ziarih Hawi

Publications and Research

Although not uncommon worldwide, consanguinity has been a part of Arab culture and tradition as a means to strengthen tribal blood relations. However, this type of union has been linked to inherited diseases, particularly those of a recessive nature (e.g., hemoglobinopathies). Furthermore, several recent studies have documented highly significant associations between consanguineous parentage and common multifactorial diseases, including but not limited to hypertension, mental disorders, and several cardiovascular diseases. In Iraq, the prevalence of consanguinity is very high and still on the rise. This has resulted in an increased prevalence of inherited diseases and has significant negative impacts on Iraq’s …

Restorative Materials And Maintenance Protocols, Renata Budny, Khrystyna Vyprynyuk

Publications and Research

No abstract provided.

Preserving Oral Health, Khrystyna Vyprynyuk, Renata Budny

Publications and Research

No abstract provided.

Restorative Materials And Maintenance Protocols, Renata Budny, Khrystyna Vyprynyuk

Publications and Research

No abstract provided.

Secondary Electrons And Compton X-Ray Generation In Solid And Heated Biological Sample In The Presence Of Radiologic Contrast Media, Vanessa Robinson, Daler Djuraev, Fatima Ahmed

Publications and Research

Our goal is identification of secondary electrons and Compton photons when externally infused radiological contrast from iodine and gadolinium interferes with calcium and iron in tissues. This could help develop next generation of x-ray methods as well as mechanistic understanding of toxic effects of radiology contrast materials on living tissue and agriculture. Changes in tissue minerals over time, aging and heat stress are manipulated in our experiments by infusing imaging contrast agents that consist of large atoms like Gadolinium and Iodine. These have chelation properties to alter electron distribution of proteins and carbohydrates of biological matrix. Our experiments try to …

Examining The Evidence Base For Burnout, Renzo Bianchi, Irvin Schonfeld

Publications and Research

Burnout has elicited growing interest among occupational health specialists in recent decades. Since 2019, the World Health Organization has characterized burnout as a syndrome resulting from chronic, unmanageable workplace stress. Accordingly, three symptoms define the entity: (i) feelings of energy depletion or exhaustion; (ii) increased mental distance from one’s job or feelings of negativism or cynicism towards one’s job; and (iii) a sense of ineffectiveness and lack of accomplishment. We call into question the definition of burnout embodied in the Maslach Burnout Inventory and incorporated into the ICD-11. We draw stakeholders’ attention to the fact that burnout’s symptoms and etiology …

Examining The Evidence Base For Burnout, Renzo Bianchi, Irvin Sam Schonfeld

Publications and Research

Burnout has elicited growing interest among occupational health specialists in recent decades. Since 2019, the World Health Organization has characterized burnout as a syndrome resulting from chronic, unmanageable workplace stress. According to the ICD-11, three symptoms define the entity: feelings of exhaustion, increased mental distance from one’s job, and a sense of ineffectiveness at work, all of which correspond to the structure of the Maslach Burnout Inventory. The ICD-11 includes burnout among the factors that influence health status. This paper calls into question that conceptualization based on a number of lines of evidence. The evidence includes the following: burnout was …

Insights Into The Molecular Roles Of Foxr2 In The Pathology Of Primary Pediatric Brain Tumors, Rajendra Gharbaran

Publications and Research

Forkhead box gene R2 (FOXR2) belongs to the family of FOX genes which codes for highly conserved transcription factors (TFs) with critical roles in biological processes ranging from development to organogenesis to metabolic and immune regulation to cellular homeostasis. A number of FOX genes are associated with cancer development and progression and poor prognosis. A growing body of evidence suggests that FOXR2 is an oncogene. Studies suggested important roles for FOXR2 in cancer cell growth, metastasis, and drug resistance. Recent studies showed that FOXR2 is overexpressed by a subset of newly identified entities of embryonal tumors. This review discusses the …

Diminazene Aceturate-Induced Cytotoxicity Is Associated With The Deregulation Of Cell Cycle Signaling And Downregulation Of Oncogenes Furin, C-Myc, And Foxm1 In Human Cervical Carcinoma Hela Cells, Rajendra Gharbaran

Publications and Research

Diminazene aceturate (DIZE) is an FDA‐listed small molecule known for thetreatment of African sleeping sickness. In vivo studies showed that DIZE may bebeneficial for a range of human ailments. However, there is very limited informationon the effects of DIZE on human cancer cells. The current study aimed to investigatethe cytotoxic responses of DIZE, using the human carcinoma Hela cell line. WST‐1cell proliferation assay showed that DIZE inhibited the viability of Hela cells in adose‐dependent manner and the observed response was associated with thedownregulation of Ki67 and PCNA cell proliferation markers. DIZE‐treated cellsstained with acridine orange‐ethidium and JC‐10 dye revealed cell …

Critical Issues In Community Health Course At Kingsborough Cc (Coh 1200) - Fall 2023, Jose Nanin

Open Educational Resources

This syllabus includes OER materials and college policies for a fully online course that exposes students to a range of topics and methods that health specialists use to research health disparities in affected communities. Through readings and videos, as well as online course assignments and discussions, students learn about library/database research methods, credibility of health information, and the health disparities most commonly occurring in modern society.

Body Movement Syllabus - The City College Of New York - Department Of Theatre - Prof Timothy Allen, Timothy J. Allen

Open Educational Resources

This course will explore three modules of learning.

1. Anatomy and Psycho-Physical Centering, will explore two foundations: (1) the start of our research and practical application of the human anatomy in regards to how our body moves; and (2) your ability to tune into movement centers within the body by utilizing Chakra as a guiding study. Please note: Anatomy will be a continuous study throughout the entire semester.

2. THE SECOND MODULE, Partnered Connection, will focus on partnering with lifts, counter-balances, falls, and rolls that will build to a partnering sequence of the tools presented.

3. THE LAST MODULE, Global Archetypes, …

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Brain Arteriovenous Malformations: The Long Way Ahead In Physics, Chemistry And Mr-Angiography Practice Before Fully Replacing Digital Subtraction Angiography., Subhendra N. Sarkar

Publications and Research

Typically, only high field systems are equipped with stronger gradients and short RF pulse designs, a must for high temporal resolution that are also responsible for high SAR, high susceptibility as well as neurostimulation. Gradient induced image noise tends to be high at 3T. Often vendors try to ameliorate such increased image noise with multi-channel head arrays and aggressive filter designs allowing an appearance of high SNR and CNR quality; however, the achievable SNR and CNR in the AVM remain limited as the analyzed articles by Zhuo et al seem to have in common. A short term solution to harvest …

Longitudinal Trends (2011–2020) Of Premature Mortality And Years Of Potential Life Loss (Ypll) And Associated Covariates Of The 62 New York State Counties, Maria-Isabel Roldos, John Orazem, Talita Fortunato-Tavares

Publications and Research

Background

New York State (NYS) is the 27th largest state and the 4th most populous state in the U.S., with close to 20 million people in 62 counties. Territories with diverse populations present the best opportunity to study health outcomes and associated covariates, and how these differ across different populations and groups. The County Health Ranking and Roadmaps (CHR&R) ranks counties by linking the population’s characteristics and health outcomes and contextual factors in a synchronic approach.

Methods

The goal of this study is to analyze the longitudinal trends in NYS counties of age‑adjusted premature mortality rate and years of potential …

Artificial Intelligence In Neuroradiology: A Scoping Review Of Some Ethical Challenges, Pegah Khosravi, Mark Schweitzer

Publications and Research

Artificial intelligence (AI) has great potential to increase accuracy and efficiency in many aspects of neuroradiology. It provides substantial opportunities for insights into brain pathophysiology, developing models to determine treatment decisions, and improving current prognostication as well as diagnostic algorithms. Concurrently, the autonomous use of AI models introduces ethical challenges regarding the scope of informed consent, risks associated with data privacy and protection, potential database biases, as well as responsibility and liability that might potentially arise. In this manuscript, we will first provide a brief overview of AI methods used in neuroradiology and segue into key methodological and ethical challenges. …

Analysis Of Imaging Database And Identifying Novel Mri Diffusion Abnormalities In Alzheimer’S Disease, Analia Basilicata, Jennifer Padilla, Anjalee Rabbani, Anam Riaz

Publications and Research

Alzheimer's disease (AD) is presumably caused by two neuropathological protein markers: amyloid beta (Aβ) and neuro fibrillary tangles. Alzheimer’s Disease Neuroimaging Initiative (ADNI) collects high quality patient data from standardized clinical trials using Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), and Cerebral Spinal Fluid (CSF) biomarkers to diagnose and evaluate the effectiveness of treatment for AD. MRI and PET screening for Alzheimer’s Disease aim to find structural, functional, and neurochemical abnormalities causing or caused by AD brain diffusion tensor imaging (DTI) and Resting State functional MRI (RSfMRI) are emerging AD MRI tools. Tau PET is a promising method for …

Classification Of Normal Versus Pneumonia From Chest X-Ray Using And Ai Model, Tassadit Lounes

Publications and Research

Hypothesis: Deep learning (DL) algorithms, in particular convolutional neural networks (CNNs), have recently been used to address a number of medical-imaging problems, such as pneumonia detection using chest X-ray, and determining the aggressiveness prostate cancer using magnetic resonance images (MRI). They have become the technique of choice in computer vision and they are the most successful type of model for image analysis.

Coh 1500 Healthcare In The Us Oer Syllabus, Shannon Caravello

Open Educational Resources

No abstract provided.

Longitudinal Trends (2011–2020) Of Premature Mortality And Years Of Potential Life Loss (Ypll) And Associated Covariates Of The 62 New York State Counties, Maria-Isabel Roldos, John Orazem, Talita Fortunato-Tavares

Publications and Research

Background

New York State (NYS) is the 27th largest state and the 4th most populous state in the U.S., with close to 20 million people in 62 counties. Territories with diverse populations present the best opportunity to study health outcomes and associated covariates, and how these differ across different populations and groups. The County Health Ranking and Roadmaps (CHR&R) ranks counties by linking the population’s characteristics and health outcomes and contextual factors in a synchronic approach.

Methods

The goal of this study is to analyze the longitudinal trends in NYS counties of age-adjusted premature mortality rate and years of potential …

The Compound Risk Of Heat And Covid-19 In New York City: Riskscapes, Physical And Social Factors, And Interventions, Janelle Knox-Hayes, Juan Camilo Osorio, Natasha Stamler, Maria Dombrov, Rose Winer, Mary Hannah Smith, Reginald Blake, Cynthia Rosenzweig

Publications and Research

Climate change is disrupting the fundamental conditions of human life and exacerbating existing inequity by placing further burdens on communities that are already vulnerable. Risk exposure varies by where people live and work. In this article, we examine the spatial overlap of the compound risks of COVID-19 and extreme heat in New York City. We assess the relationship between socio-demographic and natural, built and social environmental characteristics, and the spatial correspondence of COVID-19 daily case rates across three pandemic waves. We use these data to create a compound risk index combining heat, COVID-19, density and social vulnerability. Our findings demonstrate …

Introduction To Human Biology, Sharon S. Ellerton, Christopher Roblodowski

Open Educational Resources

This OER is intended as a textbook for a one semester introductory course in Human Anatomy and Physiology for non-science majors. It covers the major topics typically covered in A&P, but in a simplified, easier to understand manner. This textbook aims to educate students interested in lower-level health careers and non-science majors without the intimidating detail found in current textbooks. Text and images were created to be more accessible for these student populations.

Validation Of The Occupational Depression Inventory In Brazil: A Study Of 1,612 Civil Servants, Renzo Bianchi, Danísio Calixto Cavalcante, Cristina Queirós, Blezi Daiana Menezes Santos, Jay Verkuilen, Irvin Sam Schonfeld

Publications and Research

Objective: The Occupational Depression Inventory (ODI) assesses work-attributed depressive symptoms. The ODI has demonstrated robust psychometric and structural properties. To date, the instrument has been validated in English, French, and Spanish. This study examined the psychometric and structural properties of the ODI's Brazilian-Portuguese version.

Methods: The study involved 1612 civil servants employed in Brazil (MAGE = 44, SDAGE = 9; 60% female). The study was conducted online across all Brazilian states.

Results: Exploratory structural equation modeling (ESEM) bifactor analysis indicated that the ODI meets the requirements for essential unidimensionality. The general factor accounted for 91% of the common variance extracted. …

The Pandemic Anxiety Inventory: A Validation Study, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Renzo Bianchi

Publications and Research

The Pandemic Anxiety Inventory (PAI) assesses anxiety symptoms individuals attribute to the presence of a pandemic. We conducted this study of 379 British adults during the COVID-19 pandemic and found that the PAI exhibited excellent reliability and solid criterion validity. Pandemic anxiety was associated with reduced social support, anticipated life changes, financial strain, job loss, economic insecurity, and the hospitalization or death of a close friend or relative. Using correlational and bifactor analyses, we found that the PAI demonstrated solid convergent and discriminant validity. The findings suggest that the PAI can be used in research and clinical practice.

Innovations In Implant Therapy, Catherine Monchik, Isis Marsh

Publications and Research

No abstract provided.

The Pandemic Anxiety Inventory: A Validation Study, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Renzo Bianchi

Publications and Research

The Pandemic Anxiety Inventory (PAI) assesses anxiety symptoms individuals attribute to the presence of a pandemic. We conducted this study of 379 British adults during the COVID-19 pandemic and found that the PAI exhibited excellent reliability and solid criterion validity. Pandemic anxiety was associated with reduced social support, anticipated life changes, financial strain, job loss, economic insecurity, and the hospitalization or death of a close friend or relative. Using correlational and bifactor analyses, we found that the PAI demonstrated solid convergent and discriminant validity. The findings suggest that the PAI can be used in research and clinical practice.

Best Practices For Surface Disinfection, Khrystyna Vyprynyuk

Publications and Research

No abstract provided.

Effectiveness And Safety Of Apixaban Vs Warfarin In Patients With Venous Thromboembolism With Risk Factors For Bleeding Or For Recurrences, Alexander T. Cohen, Janvi Sah, Amol D. Dhamane, Dionne M. Hines, Theodore Lee, Lisa Rosenblatt, Birol Emir, Allison Keshishian, Huseyin Yuce, Xuemei Luo

Publications and Research

Introduction

Patients at increased risk of bleeding and recurrent VTE who develop venous thromboembolism (VTE) present challenges for clinical management. This study evaluated the effectiveness and safety of apixaban vs warfarin in patients with VTE who have risk factors for bleeding or recurrences.

Methods

Adult patients with VTE initiating apixaban or warfarin were identified from five claims databases. Stabilized inverse probability treatment weighting (IPTW) was used to balance characteristics between cohorts for the main analysis. Subgroup interaction analyses were conducted to evaluate treatment effects among patients with and without each of the conditions that increased the risk of bleeding (thrombocytopenia …

Serum Cotinine As A Predictor Of Lipid-Related Indices In Turkish Immigrants With Type 2 Diabetes: A Clinic-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Avinash R. Sukhram, Fatma G. Huffman

Publications and Research

Background: Turkish immigrants form the largest ethnic minority group in the

Netherlands and show a higher prevalence of (i) cardiovascular disease (CVD),

(ii) cigarette smoking, and (iii) type 2 diabetes (T2D) as compared to the native

Dutch. This study examines the association of CVD risk factors: serum cotinine, as

an indicator of cigarette smoke, and lipid-related indices among first-generation

(foreign-born) Turkish immigrants with T2D living in deprived neighbourhoods in the

Netherlands.

Methods: A total of 110 participants, physician-diagnosed with T2D, aged 30 years

and older, were recruited by convenience sampling from the Schilderswijk

neighbourhood of The Hague in a clinic-based …

Comentarios Críticos Escritos Por Estudiantes De Medicina Sobre La Evaluación Del Paciente, David Sánchez-Jiménez

Publications and Research

La presente investigación analiza los comentarios críticos producidos por estudiantes chilenos de 3º y 4º de Medicina en la sección Comentario/Reflexión final de la Ficha Clínica con el objetivo de conocer su opinión sobre la experiencia de su estancia hospitalaria y la práctica médica en general, así como de entender los elementos retórico-discursivos que utilizan para posicionar su voz en el texto al evaluar dicha experiencia. Para investigar este fenómeno se realizó un análisis textual computarizado de las categorías gramaticales y los contenidos semántico-funcionales valorativos desde un enfoque cualitativo inductivo-deductivo. Los resultados del estudio mostraron un predominio de los comentarios …

Human Retinal Organoids Release Extracellular Vesicles That Regulate Gene Expression In Target Human Retinal Progenitor Cells, Rajendra Gharbaran

Publications and Research

Introduction: Diabetic Retinopathy (DR) is a potentially blinding retinal disorder that develops through the pathogenesis of diabetes. The lack of disease predictors implies a poor prognosis with frequent irreversible retinal damage and vision loss. Extracellular Vesicles (EVs) present a novel opportunity for pre-symptomatic disease diagnosis and prognosis, both severely limited in DR. All biological fluids contain EVs, which are currently being studied as disease biomarkers. EV proteins derived from urine have emerged as potential noninvasive biomarkers.

Methods: In this study, we isolated EVs from DR retinal tissue explants and from DR patients' urine, and characterized the vesicles, finding differences in …

Coh 1700: Health Care Coordination Syllabus, Sasha Harry

Open Educational Resources

This is the syllabus for a Health Care Coordination course.

The goal of health care coordination is to improve patient outcomes with better health care services. Care coordinators play a critical role in improving patient care. Students will learn how to effectively advocate for patients and interact with members of the healthcare team in finding solutions to provide high quality, value-based, and efficient care. Effective communication styles, assessing patient’s needs and goals, and helping with patients’ transitions of care are among many topics covered in this course. Upon course completion, students will have acquired basic knowledge and skills to educate, …