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Full-Text Articles in Medicine and Health Sciences
Role Of Matrix Metalloproteinases In Animals, Sariya Asawakarn, Tanong Asawakarn
Role Of Matrix Metalloproteinases In Animals, Sariya Asawakarn, Tanong Asawakarn
The Thai Journal of Veterinary Medicine
Matrix metalloproteinases are a family of calcium-dependent and zinc-dependent endopeptidases, which excrete from many cell types. These enzymes can hydrolyze extracellular matrix proteins. The most important inhibitor of MMPs is tissue inhibitors of metalloproteinases (TIMPs). The imbalance between MMPs and TIMPs causes pathological condition in human and animals. This review focuses on structural, role and several reports of MMPs in horse, dog, cat, fish and avian. Over production of MMPs is associated with tissue destruction and erosion of cartilage in equine osteoarthritis, especially MMP-2 and MMP-9. In canine and feline, many evidences reported about MMPs and cancer such as MMP-2 …
Time Of The First Embryonic Cleavage Indicates Cat Blastocyst Quality, Nuttha Klincumhom, Ampika Thongphakdee, Mongkol Techakumphu, Kaywalee Chatdarong
Time Of The First Embryonic Cleavage Indicates Cat Blastocyst Quality, Nuttha Klincumhom, Ampika Thongphakdee, Mongkol Techakumphu, Kaywalee Chatdarong
The Thai Journal of Veterinary Medicine
Time of the first cleavage has been used as an indicator to determine developmental rate and quality of embryos in many species. The aim of this study was to examine effect of time of the first cleavage on cat embryo development and blastocyst quality. After in vitro fertilization, embryos were observed twice at 27 and 42 hours. Embryos cleaved at 27 hours post-fertilization (pf) were classified as early cleaved embryos and were separated from the remainder which were determined as delayed cleaved embryos (cleaved between 27 and 42 hours). These two groups were separately cultured in the same condition for …