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Full-Text Articles in Medicine and Health Sciences
Effects Of Erythropoietin On Blood Pressure, Renal Function And Red Blood Cell Production In Dogs With Chronic Kidney Disease With And Without Angiotensin Converting Enzyme Inhibitor, Sujittra Ritthikulprasert, Metinee Rodphol, Adthaphonl Nimrotham, Saikaew Sattayatham, Siripen Komolvanich, Monkon Trisiriroj, Chollada Buranakarl
Effects Of Erythropoietin On Blood Pressure, Renal Function And Red Blood Cell Production In Dogs With Chronic Kidney Disease With And Without Angiotensin Converting Enzyme Inhibitor, Sujittra Ritthikulprasert, Metinee Rodphol, Adthaphonl Nimrotham, Saikaew Sattayatham, Siripen Komolvanich, Monkon Trisiriroj, Chollada Buranakarl
The Thai Journal of Veterinary Medicine
Blood pressure, renal function, urinary protein excretion and red blood cell count were measured in 29 dogswith chronic kidney disease which received hormone recombinant human Erythropoietin (rHuEPO). The experimentwas divided into 2 parts. Parts 1 comprised 3 groups of dogs. Group 1 dogs were studied prior to erythropoietin(EPO) injection (pre-EPO). Group 2 dogs received EPO 100 U/kg 2-3 times a week. Group 3 dogs received both EPOand angiotensin converting enzyme inhibitor which was enalapril 5 mg/kg/daily. The duration of medication wasbetween 7 to 40 days. In part 2 of the experiment, all parameters were measured in the same dogs before …
Effects Of Meloxicam And Etoricoxib On Blood Pressure And Vascular Reactivity In Rats, P Trongtorsak, S Sukpat, D Buapool, K. Thornola
Effects Of Meloxicam And Etoricoxib On Blood Pressure And Vascular Reactivity In Rats, P Trongtorsak, S Sukpat, D Buapool, K. Thornola
Chulalongkorn Medical Journal
Background : Treatment with selective cyclooxygenase-2 (COX-2) inhibitor is associated with increased risk of cardiovascular events. Inhibition of COX-2 reduces vascular prostacyclin synthesis without disrupting COX-1-derived thromboxane synthesis, which may alter vascular tone and responsiveness. Objective : To examine the effects of two COX-2 inhibitors, meloxicam and etoricoxib, on blood pressure and vascular reactivity in rats. Methods : Unconscious blood pressure was obtained from Sprague Dawley rats by a tail-cuff method, and then the rats were divided into 3 groups (n = 9 in all groups): 1) non - treated control, 2) meloxicam 1 mg/kg/d, 3) etoricoxib 3 mg/kg/d. Drugs …