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Pleomorphic Adenoma: Review Literature, Kittipong Dhanuthai

Chulalongkorn University Dental Journal

Pleomorphic adenoma is the most common benign salivary gland neoplasm of both the major and minor salivary glands. This review article describes the clinical features, the histopathology, the immunohistochemical markers of both the epithelial and myoepithelial components, the differential diagnosis and the treatment. The histopathology of this tumor can display diverse morphological patterns, but it traditionally presents with ducts or tubules lined by inner ductal cells and outer myoepithelial cells arranged in a variety of matrix.