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Chulalongkorn University

Journal

2024

Kidney stone

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

The Electrical Conductivity Of 24-H Urine Is Decreased In Patients With Calcium Oxalate Urolithiasis., Kamonchat Boonkam Mar 2024

The Electrical Conductivity Of 24-H Urine Is Decreased In Patients With Calcium Oxalate Urolithiasis., Kamonchat Boonkam

Chulalongkorn Medical Journal

Background: Electrical conductivity (EC) of urine depends on the ionic substance-to-water ratio. Calcium oxalate (CaOx) is the most common type of urinary stone, and its formation is driven by decreased urine volume, increased lithogenic substances, and decreased stone inhibitory compounds (specifically citrate). Low urinary citrate excretion (hypocitraturia) is a prominent risk factor in Thai urolithiasis patients.

Objective: To measure the urinary EC, urinary calcium, and urine specific gravity in CaOx stone patients compared with non-stone forming (NSF) subjects.

Method: The urinary EC was measured in 24-h urine samples obtained from 42 CaOx stone patients and 121 NSF subjects. Urinary calcium …


Urinary Oxalate Excretion Is Increased In Calcium Oxalate Nephrolithiasis Patients And Associated With Increased Urinary Capacity Of Calcium Oxalate Crystallization, Chanchai Boonla Mar 2024

Urinary Oxalate Excretion Is Increased In Calcium Oxalate Nephrolithiasis Patients And Associated With Increased Urinary Capacity Of Calcium Oxalate Crystallization, Chanchai Boonla

Chulalongkorn Medical Journal

Background: Calcium oxalate (CaOx) stone is the most common type of stones formed in the urinary tract. Formation of CaOx stone is driven by increased CaOx crystallization in urine.

Objective: To develop a new test, called indole-reacted calcium oxalate crystallization index (iCOCI), and to measure the capability of urine to produce CaOx crystals.

Methods: One hundred samples of 24-h human urine samples obtained from CaOx stone-forming subjects (SFS, n = 50) and non-stone subjects (NSS, n = 50). The levels of oxalate were determined by two methods, i.e., oxalate oxidase method and iCOCI test. Unpaired student t - test, Pearson’s …