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Full-Text Articles in Medicine and Health Sciences

Alcohol-Induced Suppression Of Gluconeogenesis Is Greater In Ethanol Fed Female Rat Hepatocytes Than Males, Ken D. Sumida, Alma A. Cogger, Aleksey V. Matveyenko Jan 2007

Alcohol-Induced Suppression Of Gluconeogenesis Is Greater In Ethanol Fed Female Rat Hepatocytes Than Males, Ken D. Sumida, Alma A. Cogger, Aleksey V. Matveyenko

Physical Therapy Faculty Articles and Research

The impact of alcohol-induced suppression on hepatic gluconeogenesis (HGN) after chronic ethanol consumption between males and females is unknown. To determine the effects of chronic alcohol consumption (8 weeks) on HGN, the isolated hepatocyte technique was used on 24 h fasted male and female Wistar rats. Livers were initially perfused with collagenase and the hepatocytes were isolated. Aliquots of the cell suspension were placed in Krebs-Henseleit buffer and incubated for 30 min with lactate, [U-C-14]lactate, and nine different concentrations of ethanol (EtOH). Dose-effect curves were generated for the determination of maximal and half-maximal alcohol-induced inhibition on HGN. There was no …


Influence Of A Functional Knee Brace And Exercise On Lower Extremity Kinematics During Jogging, Brian M. Campbell, Daniel Cipriani, James A. Yaggie Jan 2007

Influence Of A Functional Knee Brace And Exercise On Lower Extremity Kinematics During Jogging, Brian M. Campbell, Daniel Cipriani, James A. Yaggie

Physical Therapy Faculty Articles and Research

ABSTRACT Context: Functional knee braces (FKB) are used prophylactically and in rehabilitation to aide in the functional stability of the knee joint. Objective: To determine if alterations in sagittal plane lower extremity kinematics remain evident throughout a one hour period in healthy individuals. Design: 2X5 repeated measures design. Setting: Biomechanics Laboratory. Subjects: Twenty subjects (14 male and 6 female, mean age 26.5±7 yrs; height 172.4±13 cm; weight 78.6±9 kg), separated into braced (B) and no brace (NB) groups. Intervention: A one-hour exercise program divided into three 20 minute increments. Main Outcome Measures: Synchronized three-dimensional …


Electromyographic Data Do Not Support A Progressive Recruitment Of Muscle Fibers During Exercise Exhibiting A Vo2 Slow Component, Daniel T. Cannon, Fred W. Kolkhorst, Daniel Cipriani Jan 2007

Electromyographic Data Do Not Support A Progressive Recruitment Of Muscle Fibers During Exercise Exhibiting A Vo2 Slow Component, Daniel T. Cannon, Fred W. Kolkhorst, Daniel Cipriani

Physical Therapy Faculty Articles and Research

The origin of the slow component (SC) of oxygen uptake kinetics, presenting during exercise above the ventilatory threshold (VT), remains unclear. Possible physiologic mechanisms include a progressive recruitment of type II muscle fibers. The purpose of this study was to examine alterations in muscle activity through electromyography (EMG) and mean power frequency (MPF) analysis during heavy cycling exercise. Eight trained cyclists (mean±S.E.; age=30±3 years, height=177±4 cm, weight=73.8±6.5 kg, VO2max=4.33±0.28lmin−1) completed transitions from 20 W to a workload equaling 50% of the difference between VT and VO2max. VO2 was monitored using a breath-by-breath measurement system, and EMG data were gathered from …