Medicine and Health Sciences Commons^™

Cell Cycle-Dependent Phosphorylation Of Nucleophosmin And Its Potential Regulation By Peptidyl-Prolyl Cis/Trans Isomerase, Xuelian Zhao, Junfang Ji, Li-Rong Yu, Timothy Veenstra, Xin Wei Wang

Pharmaceutical Sciences Faculty Publications

Nucleophosmin (NPM) is a ubiquitously expressed phosphoprotein involved in many cellular processes. Phosphorylation is considered the major regulatory mechanism of the NPM protein, associated with diverse cellular events. In this study, we characterized the phosphorylation status of several physiological phosphorylation sites of NPM, especially the newly confirmed