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Novel Targeting Approaches Of Nanoparticles For Anticancers Drug Delivery: A Focused Review, Yatri S. Patel, Nandita Das, Sudip Das Sep 2019

Novel Targeting Approaches Of Nanoparticles For Anticancers Drug Delivery: A Focused Review, Yatri S. Patel, Nandita Das, Sudip Das

Scholarship and Professional Work – COPHS

Nanoparticles have presented a new paradigm in anticancer drug delivery to reduce adverse effects and improve therapeutic outcomes. Nanoparticle surface properties and morphology significantly affect the drug delivery to tumors while passive targeting. Conjugations with hyaluronic acid, transferrin and aptamers have shown to be effective in active targeting of anticancer drugs to tumor tissues. This review presents an overview of some credible techniques of passive and active drug delivery to tumors.


Nanomedicine For The Treatment Of Non-Hodgkin Lymphoma, Tanvi Gandhi, B.Pharm Apr 2019

Nanomedicine For The Treatment Of Non-Hodgkin Lymphoma, Tanvi Gandhi, B.Pharm

BU Well

Non-Hodgkin lymphoma, or NHL, is the predominant category of lymphoma. NHL is a type of lymphoid hematopoietic malignancy which approximately 70,000 Americans are diagnosed with annually, with the number of diagnoses growing annually. For decades, chemotherapy was the standard treatment of care, but since the discovery in 1997, monoclonal antibodies are increasingly used as an alternate form of therapy. Nonetheless, almost 20,000 Americans succumb to NHL annually, which highlights the translational gap between preclinical research and the market. Although a lot of progress has been made in therapy options by immunotherapy and combination chemotherapy, the ingenuity of nanomedicine may bridge …