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Full-Text Articles in Medicine and Health Sciences
Selinexor Hyperactivates Akt And Induces Its Nuclear Accumulation, Erin Lawrence
Selinexor Hyperactivates Akt And Induces Its Nuclear Accumulation, Erin Lawrence
Honors Scholars Collaborative Projects
Selinexor is currently being used in several clinical trials for cancer and has shown anti-cancer effects in combination with other chemotherapies. Clinical trials evaluating the use of selinexor in the treatment of triple negative breast cancer are limited, but in vitro studies show promising results in its ability to kill triple negative breast cancer cells. The mechanism by which this occurs, however, is not understood. The goal of this research was to determine the mechanism by which selinexor kills BT- 549 triple negative breast cancer cells.
Unnatural Disasters: Environmental Trauma And Ecofeminist/Ecowomanist Resistance In Zora Neale Hurston’S Their Eyes Were Watching God And Jesmyn Ward’S Salvage The Bones, Sarah Anne Pfitzer
Unnatural Disasters: Environmental Trauma And Ecofeminist/Ecowomanist Resistance In Zora Neale Hurston’S Their Eyes Were Watching God And Jesmyn Ward’S Salvage The Bones, Sarah Anne Pfitzer
Honors Scholars Collaborative Projects
No abstract provided.
Effect Of Amodiaquine On Gene Expression And Apoptosis In Colorectal Cancer Cells, Holly Pyles
Effect Of Amodiaquine On Gene Expression And Apoptosis In Colorectal Cancer Cells, Holly Pyles
Honors Scholars Collaborative Projects
This study used gene expression analysis to explore the specific response to amodiaquine in HCT116 colorectal cancer cells. Real-time PCR revealed that 20 human stress and toxicity genes were upregulated by at least 3 fold in HCT116 colorectal cancer cells treated with AMQ. Of these 20 upregulated genes, 9 were found to be pro-apoptotic and 2 were DNA damage repair genes, which supports our original hypothesis that amodiaquine is inducing a stress response in these cells. These results are consistent with previous research done by Qiao et al. (2013), as DNA damage repair genes were among the genes upregulated in …
The Effects Of Language Barriers With Hispanic Patients In The Nashville, Rachel Poston
The Effects Of Language Barriers With Hispanic Patients In The Nashville, Rachel Poston
Honors Scholars Collaborative Projects
The existence of language barriers in the health care setting is a vital topic of study. This study assesses language barriers from the perspective of nurse-patient relationships, focusing on the Hispanic patient population in the Nashville, Tennessee area. A survey was designed using the Theory of Bureaucratic Caring by Marilyn Ray (2006) to investigate the current success, according to nursing perspectives, of healthcare facilities support of Hispanic patients to ensure quality outcomes and comprehension of care. The research design for this study was a non-experimental, descriptive study using a cross-sectional survey. The researcher used themes from the Theory of Bureaucratic …
Sleep Deprivation And High-Fat Diet During Adolescence Protect Stress Effects On Object Memory During Adulthood, Karina Glushchak
Sleep Deprivation And High-Fat Diet During Adolescence Protect Stress Effects On Object Memory During Adulthood, Karina Glushchak
Honors Scholars Collaborative Projects
No abstract provided.