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Full-Text Articles in Medicine and Health Sciences
Diagnostic Practices Of Autism Spectrum Disorders In Brazil, Ana Claudia Vesper Manier Dias
Diagnostic Practices Of Autism Spectrum Disorders In Brazil, Ana Claudia Vesper Manier Dias
Honors Theses
In Brazil, in spite of over half a million students with special needs in primary education, little research has been conducted about ASD diagnostic practices. This involves learning about the training that professionals are receiving, what diagnostic practices are being implemented on the field, and whether those are being contextualized according to the Brazilian culture. Students with special needs are directly affected by the results of diagnostic practices, since identifying the individuals is one of the first steps. Lack of understanding about that stage may lead to the problematic realities of underidentification or overidentification, exclusion of children who should receive …
Analysis Of Mammalian Carboxypeptidase O Expression Patterns, Christian Bardan
Analysis Of Mammalian Carboxypeptidase O Expression Patterns, Christian Bardan
Honors Theses
Carboxypeptidase 0 (CPO) is a protease that cuts acidic amino acids from the carboxy termini of substrate proteins. This study aims to describe the expression patterns of CPO in small mammals. We have sampled tissue from four different species: thirteen-lined ground squirrel, eastern chipmunk, eastern mole, and northern short-tailed shrew. Samples were analyzed via Western blot using two CPO antibodies. Immunoreactive bands likely to be CPO, with molecular weights approximately 42 kDa, were seen predominantly in kidney, liver, and intestinal tissue samples. This suggests CPO could play a specific physiological function in these organs.
The Effects Of Omega-3 Fatty Acids On Intracellular Inositol Levels In Saccharomyces Cerevisiae, Jee Yeon (Joanne) Lee
The Effects Of Omega-3 Fatty Acids On Intracellular Inositol Levels In Saccharomyces Cerevisiae, Jee Yeon (Joanne) Lee
Honors Theses
Bipolar disorder is a severe and chronic debilitating mental disorder characterized by extreme mood swings between mania and depression. The current medications for bipolar disorder, lithium and valproate, have been associated with numerous negative side effects. Although the therapeutic mechanism by which lithium and valproate (VPA) exert their effect is unknown, a leading hypothesis implicates inositol depletion as a mechanism of action. On the other hand, omega-3-fatty acids have been shown to relieve symptoms of bipolar disorder. In this study, we compare the effects of VPA to the effects of decosahexaenoic acid (DHA) on Saccharomyces cerevisiae growth and intracellular inositol …
Mobile Application For Biosensor Colorimetric Analysis, Eui Bin You
Mobile Application For Biosensor Colorimetric Analysis, Eui Bin You
Honors Theses
Inexpensive paper-based biosensors can be valuable screening tools to test for various illnesses, but it is often challenging to design them to produce a visual change that can easily be identified by untrained users. This research examines one method of compensating for the lack of distinct visual cues by developing and testing a mobile application that uses a machine learning algorithm (k-Nearest Neighbors) to analyze a picture of a sensor and determine whether it shows a positive or negative result. The machine learning algorithm was trained on a set of labeled sensor images and k-fold cross-validation was used to analyze …