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Full-Text Articles in Medicine and Health Sciences
Association Of Catechol-Omethyltransferase (Comt Val158met) With Future Risk Of Cardiovascular Disease In Depressed Individuals - A Swedish Population-Based Cohort Study, Aysha Almas, Yvonne Forsell, Vincent Millischer, Jette Möller, Catharina Lavebrat
Association Of Catechol-Omethyltransferase (Comt Val158met) With Future Risk Of Cardiovascular Disease In Depressed Individuals - A Swedish Population-Based Cohort Study, Aysha Almas, Yvonne Forsell, Vincent Millischer, Jette Möller, Catharina Lavebrat
Section of Internal Medicine
Background: Catechol-O-methyltransferase (COMT Val158Met) has been implicated in both depression and cardiovascular disease. The purpose of this study was to assess if COMT Val158Met, which influences the COMT enzyme activity, has an effect on the risk of cardiovascular disease (CVD) in individuals with a history of depression and also to determine if the risk differs depending on gender.
Methods: Data from a longitudinal cohort study of mental health among Swedish adults was used. Depression was assessed twice 3 years apart for each participant, in 1998-2001 and 2001-2003. Saliva DNA was contributed by 4349 (41.7%) of the …
Depression In Adult Patients With Primary Brain Tumours: A Review Of Independent Risk Factors, Anum Sadruddin Pidani, Aaida Mumtaz Rao, Muhammad Shahzad Shamim
Depression In Adult Patients With Primary Brain Tumours: A Review Of Independent Risk Factors, Anum Sadruddin Pidani, Aaida Mumtaz Rao, Muhammad Shahzad Shamim
Section of Neurosurgery
Depression is considered an under-diagnosed problem, especially in patients with malignancies. Patients with brain tumours in particular, have a relatively higher risk of developing depression, which is multifactorial. Herein, the authors review the recent literature on the prevalence of depression in patients with brain tumours, and explore the various risk factors involved.
Prevalence Of Positive Depression Screen Among Post Miscarriage Women- A Cross Sectional Study, Steve Mutiso, Alfred Murage, Abraham Mukaindo
Prevalence Of Positive Depression Screen Among Post Miscarriage Women- A Cross Sectional Study, Steve Mutiso, Alfred Murage, Abraham Mukaindo
Obstetrics and Gynaecology, East Africa
Background: Miscarriages are a common pregnancy complication affecting about 10–15% of pregnancies. Miscarriages may be associated with a myriad of psychiatric morbidity at various timelines after the event. Depression has been shown to affect about 10–20% of all women following a miscarriage. However, no data exists in the local setting informing on the prevalence of post-miscarriage depression. We set out to determine the prevalence of positive depression screen among women who have experienced a miscarriage at the Aga Khan University hospital, Nairobi.
Methods: The study was cross-sectional in design. Patients who had a miscarriage were recruited at the post-miscarriage clinic …