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Full-Text Articles in Medicine and Health Sciences
Mri And Mrv In Cerebral Venous Thrombosis, Zafar Sajjad
Mri And Mrv In Cerebral Venous Thrombosis, Zafar Sajjad
Department of Radiology
Although Cerebral venous thrombosis is an uncommon cause of stroke among the young, it is being increasingly recognised. A prothrombotic risk factor is identified in the majority of the patients. In most instances it is seen in women in the post-partum period and those on oral contraceptives. Magnetic Resonance Imaging (MRI) has improved our ability to diagnose this condition however the variability of radiological and clinical presentation remains a challenge. MR in combination with MR venography (MRV) is the single most sensitive diagnostic technique. The MR appearance of the thrombus within the dual sinus or cortical vein is variable and …
Mechanism Of Neuronal Injury In Cerebral Venous Thrombosis, Uzma Usman, Mohammad Wasay
Mechanism Of Neuronal Injury In Cerebral Venous Thrombosis, Uzma Usman, Mohammad Wasay
Department of Medicine
The impact of CVT on the brain is wide spectrum, ranging from completely normal parenchyma to brain oedema and/or haemorrhage. Multiple factors relate to neuronal injury in CVT including; dural sinus pressure, increased venous flow velocities, collateralization of venous channels, rate of occlusion, development of cytotoxic and vasogenic oedema, recanalization and accelerated myelination. It is suggested that recanalization of occluded vein, as well as, the presence or absence and the efficiency of intracranial venous collaterals, may have an impact on the extent of brain tissue damage and hence the prognosis of acute CVT.
Cerebral Venous System Anatomy, Muhammad Azeem Uddin, Tanveer Ul Haq, Muhammad Zafar Rafique
Cerebral Venous System Anatomy, Muhammad Azeem Uddin, Tanveer Ul Haq, Muhammad Zafar Rafique
Department of Radiology
Cerebral venous system can be divided into a superficial and a deep system. The. superficial system comprises of sagittal sinuses and cortical veins and these drain superficial surfaces of both cerebral hemispheres. The deep system comprises of lateral sinus, straight sinus and sigmoid sinus along with draining deeper cortical veins. Both these systems mostly drain themselves into internal jugular veins. The veins draining the brain do not follow the same course as the arteries that supply it. Generally, venous blood drains to the nearest venous sinus, except in the case of that draining from the deepest structures, which drain to …
Computed Tomographic Imaging Of Cerebral Venous Thrombosis, Mohammad Kamran Kamal
Computed Tomographic Imaging Of Cerebral Venous Thrombosis, Mohammad Kamran Kamal
Department of Radiology
Cerebral venous thrombosis (CVT) is an entity which is not rare and can have devastating consequences if not diagnosed and treated in a timely manner. Although, the gold standard for diagnosing this entity is a catheter angiogram, magnetic resonance venography, by virtue of its non-invasiveness and detailed demonstration of the cerebral venous structures, has become the diagnostic modality of choice for this entity. However, in a resource-strapped country like Pakistan, CT scan remains the primary first (and sometimes the only) diagnostic modality used in patients with neurological problems. Therefore, it is important to recognize the signs of cerebral venous thrombosis …
Tuberculosis Of The Scapula, Yousuf A. Husen, Naila Nadeem, Fawad Aslam, Muhammad Ali Shah
Tuberculosis Of The Scapula, Yousuf A. Husen, Naila Nadeem, Fawad Aslam, Muhammad Ali Shah
Department of Radiology
Tuberculosis (TB) of the scapula is an extremely rare presentation of osteoarticular tuberculosis. In a tuberculosis endemic setting with a rising burden of acquired immunodeficiency syndrome, this rare presentation may become more frequent. The common presentation is with longstanding Complaints of pain and swelling in the shoulder region, typically in young adults. Classic radiographic features include a well defined radiolucent lesion with minimal sequesteration. The erythrocyte sedimentation rate is usually elevated and initially these patients are frequently mis-diagnosed and thus a high index of clinical suspicion is required. Medical therapy with antituberculous drugs is the standard modality of treatment. This …
Evaluation Of Erectile Dysfunction With Color Doppler Sonography, Vaqar Bari, M Nadeem Ahmed, M Zafar Rafique, Kashif Ashraf, Waseem Ahmad Memon, M Uzair Usman
Evaluation Of Erectile Dysfunction With Color Doppler Sonography, Vaqar Bari, M Nadeem Ahmed, M Zafar Rafique, Kashif Ashraf, Waseem Ahmad Memon, M Uzair Usman
Department of Radiology
Objective: To assess the role of Color Doppler Sonography in the evaluation of erectile dysfunction.Methods: A cross-sectional study was conducted at the Radiology Department, Aga Khan University Hospital Karachi from 5-6-2002 to 2-9-2003. All consecutive patients presenting with erectile dysfunction and undergoing penile color Doppler evaluation with injection PGE1 20 mcg were included in this study.Results: A total of 70 patients with an age range of 24-70 years (mean 41 +/- 12.25 years) were included in the study. A normal response was noted in 45 (psychogenic) cases. Vasculogenic causes were observed in 23 patients, 12 with arterial insufficiency and 11 …
Extra [Corrected] Pulmonary Uptake Of Tc-99m-Maa Perfusion Lung Scan As A Result Of Right To Left Intra Cardiac Shunt, Riffat Hussain, Maseeh-Uz-Zaman, Sohail Abrar Khan, M Nadeem Ahmad
Extra [Corrected] Pulmonary Uptake Of Tc-99m-Maa Perfusion Lung Scan As A Result Of Right To Left Intra Cardiac Shunt, Riffat Hussain, Maseeh-Uz-Zaman, Sohail Abrar Khan, M Nadeem Ahmad
Department of Radiology
Extra pulmonary accumulation of Tc-99m-macroaggregate of albumin (MAA) is rarely seen on perfusion lung scan, and has been reported in less than 4% of a study population of nearly 380 patients. It occurs when the agent bypasses the lungs due to a right to left (R-L) cardiac or pulmonary shunt, when it is shunted to the portal vein before reaching the right atrium and ventricle of the heart, and when the agent is degraded to a submicron particle size. When a pharmaceutical problem is excluded, extra-pulmonary uptake implies unusual hemodynamics with a shunt. A case is reported in which a …
Role Of Focused Appendiceal Computed Tomography In Clinically Equivocal Acute Appendicitis, Kashif Ashraf, Omer Ashraf, Vaqar Bari, Muhammad Zafar Rafique, Muhammad Uzair Usman, Ishtiaq Chisti
Role Of Focused Appendiceal Computed Tomography In Clinically Equivocal Acute Appendicitis, Kashif Ashraf, Omer Ashraf, Vaqar Bari, Muhammad Zafar Rafique, Muhammad Uzair Usman, Ishtiaq Chisti
Department of Radiology
Objective: To determine the accuracy of FACT (focused appendiceal computed tomography) in evaluation of acute appendicitis.Methods: The study was conducted in Aga Khan University Hospital, Karachi, over a period of one year. Sixty-three patients with clinically equivocal acute appendicitis underwent thin-section non-enhanced helical CT. Axial scans were obtained in a single breath hold from L2 vertebral level to the pubic symphysis with 5-mm collimation and a pitch of 1.5. All scans were obtained without oral, intravenous, or rectal contrast material. Criteria for diagnosis of acute appendicitis included an enlarged appendix (>6 mm diameter) and periappendiceal inflammation. Final diagnoses were …
Colorectal Carcinoma, Preoperative Evaluation By Spiral Computed Tomography, Kashif Ashraf, Omer Ashraf, Zeeshan Haider, Zafar Rafique
Colorectal Carcinoma, Preoperative Evaluation By Spiral Computed Tomography, Kashif Ashraf, Omer Ashraf, Zeeshan Haider, Zafar Rafique
Department of Radiology
Objectives: To assess the capability of spiral computed tomography (CT) scan in preoperative evaluation of colorectal carcinoma (CRC).Methods: A cross sectional study on 52 patients with recent histopathologic diagnosis of CRC was conducted over a period of one year at the Aga Khan University Hospital, Karachi. All these patients underwent spiral CT with oral and intravenous contrast administration. Surgery was subsequently done in all cases and surgical specimens were sent for detailed pathologic analysis. The radiologic findings on the CT scans were compared with the pathological findings.Results: The results proved that spiral CT had 60% sensitivity and 83% specificity for …
Sentinel Lymph Node Scintigraphy And Radioguided Dissection In Breast Carcinoma: An Initial Experience At Aga Khan University Hospital, Maseeh Uz Zaman, Shaista Khan, Riffat Hussain, M Nadeem Ahmed
Sentinel Lymph Node Scintigraphy And Radioguided Dissection In Breast Carcinoma: An Initial Experience At Aga Khan University Hospital, Maseeh Uz Zaman, Shaista Khan, Riffat Hussain, M Nadeem Ahmed
Department of Radiology
Objective: To evaluate the efficacy of SLN biopsy using imaging and gamma probe in breast cancer and to establish this technique at Aga Khan University Hospital.Methods: Thirty two patients (mean age 33-76 yrs) with operable breast carcinoma (4 with post-neo adjuvant therapy) with clinically negative axilla were studied. In 28 patients simultaneous axillary dissection was performed. Sentinel lymph nodes (SLN) scintigraphy was performed a day before surgery by injecting Tc-99m labeled nannocolloid sub-dermally in the peri-areolar region in 24 and peri-tumoral in remaining 8. First lymph node (LN) to appear to on the scan was labeled as SLN and marked …
Median Survival Time Of Patients After Transcatheter Chemo-Embolization For Hepatocellular Carcinoma, Zeeshan Haider, Haq Ul, Khalid Munir, M Uzair Usman, Muhammad Azeemuddin
Median Survival Time Of Patients After Transcatheter Chemo-Embolization For Hepatocellular Carcinoma, Zeeshan Haider, Haq Ul, Khalid Munir, M Uzair Usman, Muhammad Azeemuddin
Department of Radiology
Objective: To determine the effect on survival after transarterial chemoembolization (TACE) in patients with unresectable hepatocellular carcinoma (HCC).Design: Longitudinal cohort study.PLACE AND DURATION OF STUDY: Radiology Department, The Aga Khan University Hospital, Stadium Road, Karachi, from December 1997 to September 2005.PATIENTS AND Methods: Patients undergoing TACE procedure for HCC were prospectively followed. Fortythree patients were enrolled from December 1997 to March 2003 in the study and subjected to chemoembolization therapy. Eight out of 43 patients were excluded from the study, who lost to follow-up. All the patients were followed till their death. Median and mean survival were calculated.Results: The median …
Gift Authorship Practices - History, Trends And Remedies, Saba Sohail
Gift Authorship Practices - History, Trends And Remedies, Saba Sohail
Department of Radiology
No abstract provided.