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Full-Text Articles in Medicine and Health Sciences

Metachronous Second Primary Malignancy In Head And Neck Cancer Patients: Is Five Years Of Follow-Up Sufficient?, Muhammad Adeel, Moghira Siddiqui Oct 2018

Metachronous Second Primary Malignancy In Head And Neck Cancer Patients: Is Five Years Of Follow-Up Sufficient?, Muhammad Adeel, Moghira Siddiqui

Section of Otolaryngology, Head & Neck Surgery

Objectives: The aim of this study was to determine the incidence and characteristics of second primary malignancy (SPM) in patients with head and neck squamous cell carcinoma treated at a tertiary care hospital.
Materials and methods: We retrospectively reviewed the medical records of 221 patients who underwent surgery with or without adjuvant treatment for head and neck cancer from 2000 to 2002. Data of age, sex, risk factors, sites of primary and SPM, TNM stage of primary tumor, incidence of SPM, and survival were collected from medical charts.
Results: Eighteen patients developed SPM during a median follow-up of 67 months, …


Quality Of Life After Functional Endoscopic Sinus Surgery In Patients With Chronic Rhinosinusitis, Sadaf Qadeer, Shabbir Akhtar, Montasir Junaid, Muhammad Sohail Halim Jul 2018

Quality Of Life After Functional Endoscopic Sinus Surgery In Patients With Chronic Rhinosinusitis, Sadaf Qadeer, Shabbir Akhtar, Montasir Junaid, Muhammad Sohail Halim

Section of Otolaryngology, Head & Neck Surgery

Chronic Rhinosinusitis (CRS) is a group of disorders characterized by the inflammation of mucosa of the nasal passages and paranasal sinuses. It includes chronic rhinosinusitis with polyps, CRS without polyps and Allergic Fungal Sinusitis (AFS). This debilitating disease causes negative impact on quality of life (QOL) of patients. Functional endoscopic sinus surgery (FESS) is the mainstay of surgical treatment for patients and improves QOL of patients. This subjective assessment of QOL can be measured by disease specific questionnaires. SNOT-22 questionnaire is widely used and validated questionnaire for this purpose. Prospective study was done on 54 patients. Data were collected using …


Unusual Presentation Of Differentiated Thyroid Cancer Metastasis, Haissan Iftikhar, Mubasher Ikram, Adnan Yar Muhammad, Karim Rizwan Nathani Apr 2018

Unusual Presentation Of Differentiated Thyroid Cancer Metastasis, Haissan Iftikhar, Mubasher Ikram, Adnan Yar Muhammad, Karim Rizwan Nathani

Section of Otolaryngology, Head & Neck Surgery

Introduction  The rates of thyroid cancers are on a rise, especially well-differentiated thyroid cancers. This could be partly due to newer diagnostic modalities, like high-resolution ultrasound, that can pick up smaller lesions. Differentiated thyroid cancers with distant metastases are not common, and even rarer is the initial presentation with complaints not related to the neck.

Objectives  The objective of this series was to study and report the unusual cases of patients with differentiated thyroid cancer with distant metastasis. There is a lack of data in the literature on these cases, and due to the rarity of such metastases, no definite …


Frequency Of Cervical Nodal Metastasis In Early Stage Squamous Cell Carcinoma Of The Tongue, Sadaf Qadeer Ahmed, Montasir Junaid, Mohammad Sohail Awan, Maliha Kazi, Hareem Usman Khan, Sohail Haleem Apr 2018

Frequency Of Cervical Nodal Metastasis In Early Stage Squamous Cell Carcinoma Of The Tongue, Sadaf Qadeer Ahmed, Montasir Junaid, Mohammad Sohail Awan, Maliha Kazi, Hareem Usman Khan, Sohail Haleem

Section of Otolaryngology, Head & Neck Surgery

ntroduction Oral cavity carcinoma is an aggressive tumor, with the tongue being one of the most common subsites of involvement. Surgery is a gold standard method of dealing with advanced-stage tumors. However, for early-stage carcinomas of the tongue, the management remains controversial. Several studies have indicated that early-stage cancers have a high chance of occult cervical node metastasis, which, if left untreated, can greatly affect the prognosis. Certain parameters can help identify patients with occult cervical node metastases, and can avoid unnecessary neck dissection in node negative patients. Tumor thickness is one such objective parameter. Objective To estimate the frequency …