Medicine and Health Sciences Commons^™

Exploring Available Information On The Gut-Brain Axis And Alzheimer’S Disease For Clinicians Making Dietary Recommendations: A Scoping Review, Megan Gibson

Electronic Theses and Dissertations

Abstract: Alzheimer’s Disease (AD) is a complex neurodegenerative disease that requires interprofessional collaboration. Pharmacological options are currently ineffective, increasing the need for preventative strategies to combat the rise of AD. Considerations of gut-targeted interventions have increased as a key component in the prevention of AD, based on the understanding that the state of the gut microbiome can impact cognitive function through the pathway known as the gut-brain axis.

Methods: This scoping review explored information on the gut-brain axis in persons with AD. A comprehensive search was conducted in November 2023. Forty reviews and 13 human studies were analyzed.

Results: There …

Nutritional Deuterium Depletion And Health: A Scoping Review, Nicole Korchinsky

Department of Nutrition Student Projects

Background: Deuterium depletion is an untapped area of energy metabolism and health.

Objectives: The purpose of this scoping review is to examine the health effects through deuterium depletion via deuterium-depleted water and a deuterium-depleted diet (ketogenic).

Methods: A protocol process approach was used to retrieve current research in deuterium depletion.

Results: 15 research articles were used. Deuterium depletion was found to have beneficial health effects in the following conditions: cancer prevention, cancer treatment, depression, diabetes, long-term memory, anti-aging, and sports performance.

Conclusion: Even with limited data, consistent deuterium depletion was seen across all conditions reviewed. …

Prescribing Flavor: Proposal For A Longitudinal Culinary Medicine Curriculum In A Family Medicine Residency Program, Mario F. Jacome Jr

Department of Nutrition Student Projects

Culinary medicine is gaining recognition as an essential component of healthcare, aiming to integrate food and nutrition into medical practice for managing chronic diseases. However, there is a significant gap in nutrition education within medical schools and residency programs, leaving healthcare professionals ill-equipped to address patients' dietary concerns. This proposal presents a comprehensive longitudinal curriculum blueprint for culinary medicine tailored to family medicine residents. The curriculum emphasizes hands-on learning, collaborative cooking opportunities, and practical counseling techniques to empower residents in addressing nutrition-related diseases effectively. Through a structured approach and innovative educational strategies, this initiative aims to enhance resident proficiency and …

Hhp-8 Barriers And Facilitators To Regular Physical Activity And Healthy Eating Behaviors In Schools: Perspectives Of South Carolina School Personnel, Logan J. Camp-Spivey, Susan D. Newman, Robert N. Stevens, Michelle Nichols

SC Upstate Research Symposium

Background: In South Carolina (SC), 42% of youth are overweight or obese. Two sets of modifiable behaviors contributing to obesity are physical activity (PA) and dietary habits. School-based interventions have successfully improved these behaviors. The purpose of this study was to identify SC public school personnel perspectives on the most common barriers and facilitators to regular PA and healthy eating behaviors in schools.
Methods: A needs assessment survey was conducted with school personnel statewide. There were 17 questions on the survey that addressed: (1) demographic information about participants’ educational backgrounds, (2) barriers to regular PA and healthy eating behaviors in …

Effect Of Medically Tailored Meals On The Physical Health Of Patients With A Cancer Diagnosis, Deeksha Ajeya, Jule Anne Henstenburg

Tower Health Research Day

No abstract provided.

Impact Of Fads Genotype On Polyunsaturated Fatty Acid Content In Human Milk Extracellular Vesicles: A Genetic Association Study, John J. Miklavcic, Natalie Paterson, Jennifer Hahn-Holbrook, Laura M. Glynn

Food Science Faculty Articles and Research

Background

Extracellular vesicles in human milk are critical in supporting newborn growth and development. Bioavailability of dietary extracellular vesicles may depend on the composition of membrane lipids. Single-nucleotide polymorphisms (SNPs) in the fatty acid desaturase gene cluster impact the content of long-chain polyunsaturated fatty acids in human milk phospholipids. This study investigated the relation between variation in FADS1 and FADS2 with the content of polyunsaturated fatty acids in extracellular vesicles from human milk.

Methods

Milk was obtained from a cohort of mothers (N = 70) at 2–4 weeks of lactation. SNPs in the FADS gene locus were determined using …

"Fueling For A Healthy Life:" A Cooking Class For Adolescent And Young Adult Childhood Cancer Survivors, Hope Dominique

Senior Theses

Following cancer treatment, childhood cancer survivors (CCS) are at an increased risk of developing chronic diseases and face an increased risk of health-related death during adulthood. Recent literature demonstrates that modifying lifestyle factors such as nutrition can reduce the risk of late mortality in survivors, suggesting that interventions promoting a healthy lifestyle may improve quality and quantity of life for CCS. However, many adolescent and young adult (AYA) CCS do not adhere to national dietary guidelines and face both real and perceived barriers to adopting healthier eating habits while in a critical period for establishing behaviors that contribute to lifelong …

The Health Effects Of Chocolate: A Literature Review, Erika A. Pierce

Senior Theses

Chocolate has been a part of the human diet for centuries, but while it was once considered a healthy food, it is now seen as a dessert and unhealthy treat. It is known that chocolate contains polyphenols, flavonoids, and minerals that can affect body functioning. To determine the extent to which chocolate plays a role in health, a literature review was performed by searching the PubMed, CINAHL, and Web of Science databases for peer-reviewed articles published between 2004 and 2024. Of the 14 included studies, the health effects of chocolate fell into three overarching categories: neurological effects, including mental health, …

Healthy Hearts: An Interactive Demonstration To Increase Interest In Medicine In Elementary/ Middle School Students In/Around Detroit., Neha Chava, Jessica Elderkin, Austin Kim, Molly Dahle, Rohit Goru, Karamoja Monchamp, Neeraj Ochaney, Meghan Dwaihy Md, Mph

Medical Student Research Symposium

There continues to be a lack of representation and diversity in higher education today, especially in medicine and healthcare. As part of the Healthy Hearts student organization at Wayne State University School of Medicine, we developed a one-time educational session and interactive demonstration to teach students about heart and lung health and fuel students’ enthusiasm for healthcare. This project serves as a quality improvement study to understand how we can increase STEM interest in elementary and middle school students in and around Detroit, Michigan. A three question pre- and post-intervention survey was constructed to measure change in: 1) interest in …

Assessing The Differences Between Chewing And Swallowing Arugula Extract Capsules On The Concentrations Of Nitric Oxide Metabolites In Metabolically Healthy Males, Tomas J. Chapman-Lopez, Leroy Bolden, Dylan T. Wilburn, Jeffery L. Heileson, Rodney Sturdivant, Andrew R. Gallucci, Leslee K. Funderburk, Jeffrey S. Forsse

International Journal of Exercise Science: Conference Proceedings

Previous literature has examined the benefits of consuming nitrate (NO3)-rich crops (e.g., beetroot, spinach, watercress, arugula) on endothelial function due to their positive influence on nitric oxide (NO) production from the utilization of nitrate-reducing bacteria in the oral microbiome. However, there has yet to be a study addressing how the method of consumption may influence the role the oral microbiome plays in the degradation of NO3 to NO from consuming an encapsulated NO3-rich crop. PURPOSE: To determine the differences in NO metabolite concentrations following two different methods (e.g., chewing, swallowing) of consuming the encapsulated arugula extract. METHODS: Eight, …

Nutrition Able: A Lecture-Based Intervention To Promote Nutritional Literacy About Protein Intake In Women, Jeffery Bolte, Alejandra Garcia, Jacob Abalos, Jakson Johnson, Alex Joyce, Christopher Hinds, Jared Tuttle, Jeff Svec

International Journal of Exercise Science: Conference Proceedings

Sport performance is influenced by sport-specific requirements for body composition. One major predictor of body composition is protein intake. Higher protein intake tends to cause leaner body composition relative to lower protein intake, especially during caloric deficit. In Bexar County, ~72% of the adult population is overweight/obese and 15.5% are diabetic. This suggests that high protein diet could be a high leverage option in the San Antonio population for optimizing body composition for sport performance. Furthermore, late life sporting activity and protein intake is a primary method for mitigating sarcopenia, osteoporosis, fractures, and accidental death in post-menopausal women. PURPOSE: …

Challenges Of Competency Management For Dietetics Program And Internship Directors: An Application Of Design Thinking, David Gaviria, Elizabeth Chen

Journal of Dietetic Education

Objective: Dietetics education transitioned to competency-based education (CBE) in July 2022. Despite its benefits, managing competencies may be a challenging aspect of CBE for dietetics program and internship directors (PDIDs), yet it is unclear what specific aspects of competency management are difficult. Using design thinking, this study sought to capture the impact recent CBE implementation had on PDIDs by identifying specific pain points (i.e., challenges) related to competency management. The results of this work serve to document such pain points and may be used to generate solutions to address or eliminate the pain points. For example, this research can support …

The Effectiveness Of Jeffwlp For Weight Loss And General Nutritional Knowledge In Obese Patients, Scott Kozarsky, Ba, Olivia Ackley, Bs, Cynthia Cheng, Md, Phd

Alpha Omega Alpha Research Symposium Posters

PURPOSE: The increasing prevalence of obesity urgently requires effective management strategies. This study evaluates the effectiveness of Jefferson Weight Loss Program (JeffWLP), a trained medical student-delivered health education program in a predominantly African-American patient cohort.

METHODS: A randomized controlled trial was performed enrolling 30 patients with an average socioeconomic status of 5.8 (10 maximum). The intervention group (n=18) completed JeffWLP, a low-cost, 12-week health coaching program combining education sessions with graded step exercises. The control group (n=12) received usual care. Mean baseline age, BMI, and General Nutritional Knowledge Questionnaire (GNKQ) scores were: 46±13 years, 38±5, and 14.7±1.9 (maximum score=17) respectively. …

The Prevalence Of Cardiac Risk Factors In College-Aged Students, Katelyn Butczynski, Brianna Fox, Kristen Mccloskey, Katrina Redline

Student Research Poster Presentations 2024

Background: The impact of Cardiovascular disease (CVD) is typically associated with adulthood. However, its roots can be traced back to childhood. The transition from high school to college includes many lifestyle and environmental changes, which can lead to the creation of new lifelong habits. The college experience can contribute to the development of CVD risk factors with these new lifestyle changes. These risk factors lead to the development of CVD in adulthood.

Aims: This study was conducted to determine the prevalence of CVD in college-aged students and identify their risk for developing CVD in adulthood.

Methods: The study was a …

Improving Nutrition Education And Access To Healthy Food For Low-Income Mainers, Jessica Wyn

Family Medicine Clerkship Student Projects

Many people in Androscoggin county are not able to consistently achieve a diet with the recommended food variety for improving health. Adequate nutrition for improving health outcomes requires access to healthy food at affordable prices, health literacy regarding diet and nutrition concepts, and the skills and access to equipment required to prepare and store food. A lack of resources in any one of these areas can limit a person’s ability to engage in a healthy diet, which increases their risk of developing preventable non-communicable diseases later in life.

Nutritional Support For Oncology Patients: Role For The Pcp, Annabelle S. Feist

Family Medicine Clerkship Student Projects

Adequate nutrition is a key prognostic factor in the treatment outcomes of patients with cancer diagnoses. Despite the increased morbidity and mortality of malnutrition, the importance of nutrition for oncology patients is often not well communicated and not well understood by patients. Part of this issue stems from the limited information most patient can absorb at any given doctors appointment, especially regarding their cancer. Primary care providers hold a unique position to fill this gap and have the information be heard and retained given their usual role in addressing overall health. This project compiles resources in an easily accessible and …

Improving Nutrition Screening Practice In The Hospitalized Heart Failure Patient Population, Amanda J. Bourgeois

DNP Projects

Background: Heart Failure is a disease known to affect nearly 6.5 million adults in the United States. Characterized by recurrent hospitalizations, heart failure significantly contributes to morbidity, mortality, and healthcare costs in the United States and worldwide. Because malnutrition is prevalent in the heart failure population, healthcare providers must perform nutritional assessments on admission to intervene in the case of malnutrition, prevent deterioration, and improve patient prognosis. Without intervention and early identification of malnutrition, heart failure hospitalizations will remain a significant problem.

Purpose: The purpose of this study is to evaluate the effect of an evidence-based educational program for cardiac …

The Nurse's Lived Experience Of Transferring Nutrition Knowledge To Patients: A Descriptive Phenomenology, Kendrah Lynne Cunningham

Doctoral Dissertations and Projects

This descriptive phenomenological qualitative study aimed to gain insight into the nurse’s lived experience of transferring nutrition knowledge to patients. Nurses play an important role in assisting the patient to become more proficient in health and nutrition literacy to make proper choices related to their nutrition. It is necessary to evaluate the lived experience of the nurse in transferring nutrition knowledge to patients. There is a gap in the literature on nurses’ experience in providing nutrition knowledge to their patients. This descriptive phenomenological qualitative study examines the lived experience of nurses in transferring nutrition education to their patients. This was …

Electronic Nicotine Delivery Systems Use And Periodontal Health—Findings From The Population Assessment Of Tobacco And Health Study, Amir Mohajeri, Martin S. Lipsky, Rachana Hegde, Jody Chiang, Man Hung

Institute on Aging Publications

Background: Electronic nicotine delivery systems (ENDSs) are rapidly increasing in the U.S., however, information about their long-term risks and benefits remains limited. This study examined the relationship between ENDS use and periodontal health among U.S. adults. (2) Methods: Data came from 33,822 adults who participated in the 2016–2018 wave of the Population Assessment of Tobacco and Health (PATH) study. Inclusion criteria were adults without a history of cigarette smoking or diabetes. Logistic regression analysis was performed to estimate the associations between ENDS use and a history of periodontal disease, with multivariable logistic regression adjusting for factors associated with poor oral …

Multi-Domain Interventions For Dementia Prevention–A Systematic Review, C. B. Castro, L. M. Costa, C. Max B. Dias, J. Chen, H. Hillebrandt, Samantha L. Gardener, B. M. Brown, R. L. Loo, M. L. Garg, Stephanie R. Rainey-Smith, Ralph N. Martins, Hamid R. Sohrabi

Research outputs 2022 to 2026

Objectives: There is a growing incidence of cognitive decline and dementia associated with the ageing population. Lifestyle factors such as diet, physical activity, and cognitive activities may individually or collectively be undertaken to increase one’s odds of preventing cognitive decline and future dementia. This study will examine whether clinical trials using multidomain lifestyle intervention can significantly decrease the risk of cognitive decline and therefore dementia. Design, Setting and Participants: This systematic literature review of multidomain lifestyle interventions for the prevention of cognitive decline and dementia followed the PRISMA guidelines. Clinical trials involving multidomain intervention (i.e., diet and physical activity, or …

Pili Pono Practice: A Qualitative Study On Reimagining Native Hawaiian Food Sovereignty Through Malama Backyard Aquaponics, Pahonu Coleman, Samantha Keaulana, J Kahaulahilahi Vegas, Phoebe W. Hwang, Leshay Keliiholokai, Jane J. Chung-Do, Ikaika Rogerson, Ilima Ho-Lastimosa

Journal of Health Disparities Research and Practice

Living in one of the most remote island chains in the world, Native Hawaiians developed sophisticated food cultivation systems that sustained a thriving and robust population for centuries. These systems were disrupted by colonization, which has contributed to the health disparities that Native Hawaiians face today. MALAMA, a culturally-grounded backyard aquaponics program, was developed to promote food sovereignty among Native Hawaiians. This study utilized participant interview and focus group data to identify how participating in the MALAMA program impacts the wellbeing. The findings demonstrate that MALAMA enhanced the participants’ pilina (relationship, connection) to traditional foods, land, cultural identity, family, and …

Adapting The Aha’S Blood Pressure And Nutrition Management Program Into Digestible Teaching Plans For Low-Income Communities, Truc Huynh, Jemina Lynn B. Estepa, Fritz Reanne A. Obungen, Katelyn Marie Clasey, Kirsty Keitges, Serah M. Kimani, Hailey Rae Tauscheck, Andrew David Rhoades

Nursing Leadership in Community Engagement Projects

Executive Summary: Adapting the AHA’s blood pressure and nutrition management program into digestible teaching plans for low-income communities

According to the American Heart Association (AHA), 46% of American adults have high blood pressure (Whelton et al., 2017). High blood pressure, especially for those above the age of 50, is associated with a higher prevalence of heart disease and a shorter life expectancy. The AHA’s Check Change Control program (CCC), is an evidence based, self-directed blood pressure management guide (American Heart Association, 2021). The CCC program incorporates four lesson topics related to lifestyle changes to manage hypertension. The four topics are: …

Food And Mood: Investigating The Correlation Between Vitamin B12 Intake And Depression, Jana Soucar, Hawley Almstedt

International Journal of Exercise Science: Conference Proceedings

Vitamin B12 is an essential nutrient that metabolizes homocysteine, which is a potentially neurotoxic molecule when in excess. Studies show that a deficiency in vitamin B12, as well as folate, may be associated with mental health conditions. Additionally, the prevalence of depression is higher in college students than other demographic populations. PURPOSE: The purpose of this study was to investigate a correlation between vitamin B12 and folate intake with signs and symptoms of depression in college students. METHODS: This study was conducted by first providing participants with the Beck Depression Inventory (BDI) to measure signs and symptoms of …

Fluid Intake And Hydration Responses To Mass Participation Gravel Cycling, Brandon Raik, Francis Salmon, Grace Handler, Matthew M. Schubert

International Journal of Exercise Science: Conference Proceedings

Gravel cycling is a relatively new cycling discipline, with the Union Cycliste Internationale (UCI) hosting their first UCI Gravel World Championships in 2022. Gravel races combine features of road racing, cyclocross, and mountain biking, including various terrain of varying technical difficulty (paved roads, dirt roads, fire roads, single- and double-track trails), long distances, substantial vertical elevation gain, obstacles, and limited opportunities to stop for in-race nutrition. PURPOSE: To date, gravel racing has not been scientifically examined to determine the demands of the sport. Data from cycling road races indicate substantial fluid loss, which may impair exercise performance. This study assessed …

Dietary Inflammatory Index Score And Its Association With Body Mass Index, Body Fat Percentage, Body Fat Mass, And Lipid Profile In Patients With Multiple Sclerosis, Seda Kaya, Zeynep Uzdi̇l, Ni̇ti̇n Shi̇vappa, James R. Hebert, Pinar Sökülmez Kaya, Murat Terzi̇

Turkish Journal of Medical Sciences

Background/aim: Multiple sclerosis (MS) may cause modifications in body composition, particularly for body fat associated with obesity and some biochemical parameters such as lipid profiles. We investigated whether there is a link between the inflammatory contents of diets and body composition and lipid profiles in patients with MS. Materials and methods: This was a cross-sectional study that included 85 MS patients. The study data of the patients were collected in the Neurology Clinic of Ondokuz Mayıs University?s Health Practice and Research Center. The data included demographic characteristics; anthropometric measurements such as body weight, height, body mass index, waist circumference, hip …

Implementation Of Nutritional Screening In Adults (Ages 19-65) With Major Depressive Disorder: An Integrative Review, Laurie S. Stephens

Doctoral Dissertations and Projects

The World Health Organization estimates the total percentage of depression at 3.8% and projects it to be the leading cause of global disability by 2030 (WHO, 2023). The economic burden for adults with major depressive disorder in the United States is estimated at a staggering annual cost of 236 billion dollars (Greenberg et al., 2018). Nutritional psychiatry is a growing subspecialty focused upon how diet can improve mental health outcomes. The evidence shows a correlation between diet and depression, influencing questions on how this translates to current dietary recommendations and treatment. An integrative review of current literature was performed to …

The Impact Of Modern Dietary Practices On Cancer Risk And Progression: A Systematic Review, Stephanie Nagy, Stephanie N. Petrosky, Michelle Demory Beckler, Marc M. Kesselman

HPD Articles

Cancer is a leading cause of mortality around the world, despite continued advancements in the management of cancer. Recent research efforts have shifted to evaluating the role that modifiable risk factors play in cancer risk and development, as diet and nutrition have been found to play a significant role in the onset and progression of cancer. As a result, there has been an increasing focus on the impact of dietary modifications on preventing the onset, progression, and reoccurrence of cancer. In this systematic review, data were collected on three common diets, the Mediterranean diet (MD), ketogenic diet (KD), and plant-based …

Nutritional Knowledge, Attitudes, And Practices Among Family Physician Practitioners In Gulf Countries (Bahrain, Kuwait, Saudi Arabia, And Uae), Abeer S. Alzaben, Abeer A. Aljahdali, Lulua F. Alasousi, Ghadeer Alzaben, Lynne Kennedy, Anwar Alhashem

All Works

Family physicians serve as pivotal points of contact within global healthcare systems. Nutrition plays a significant role in lifestyle and preventive medicine. With the rise of chronic and non-communicable diseases in Gulf Cooperation Council (GCC) countries, these physicians advise patients and the public on diet-related conditions. This descriptive cross-sectional study assessed the nutritional knowledge and practices across the GCC. Combining survey data from multiple GCC sites, a sample of family physicians was generated. Registered GCC family physicians received email invitations containing participant information, informed consent forms, and a self-administered online questionnaire. Analysis of data from four GCC countries involving 8751 …

Revisiting The Master Food Volunteer Program: Examining How To Enhance Nutrition Education In The United States, Stacey Viera, Lindsey Haynes-Maslow

The Journal of Extension

America’s diet-related illness crisis intersects with a lack of nutrition literacy, nutrition security, and systemic inequities. The Cooperative Extension Service’s (CES) national infrastructure could potentially provide equitable access to quality nutrition education in the US utilizing a Master Food Volunteer (MFV) model. This research brief examined preliminary evidence for the MFV model as a support for CES agents and paraprofessionals, and results show a paucity of evidence. Further research and a pilot program with pre-established measures for health-related knowledge and behaviors could elucidate the model’s potential to increase equitable access to evidence-based programming, nutrition, and implementation guidance.

Nutrition-Related Experiences Of Women With Perinatal Depression During The Covid-19 Pandemic: A Qualitative Study, Dahlia Stott, Cynthia Klobodu, Lisa A. Chiarello, Bobbie Posmontier, Mona Egohail, Pamela A. Geller, June Andrews Horowitz, Brandy-Joe Milliron

College of Nursing Faculty Papers & Presentations

Women with perinatal depression are at a high risk for unhealthy dietary behaviors but whether the coronavirus disease 2019 (COVID-19) pandemic has exacerbated this risk is unknown. Here we report the findings of a qualitative study exploring the impact of the COVID-19 pandemic on nutrition-related experiences of women with perinatal depression. Using a qualitative descriptive approach, in-depth interviews were conducted with 18 women with a history of perinatal depression and 10 healthcare providers. A semistructured format elicited how food and nutrition-related behaviors of women with perinatal depression were affected by the COVID-19 pandemic. Thematic analysis identified 4 themes related to …