Medicine and Health Sciences Commons^™

Age-Related Sonoanatomical Change Of The Knee In Children, Shu-Mei Yang, Chia-Wei Lin, Wen-Shiang Chen

Rehabilitation Practice and Science

Ultrasound has been thoroughly studied and become a well-established tool for assessment of adult patients' musculoskeletal system both in research and clinical practice. However, the use of musculoskeletal ultrasound in pediatric populations is still limited. The age-dependent variability of normal sonoanatomy dueto bone maturation and ossification in children is the main limitation to establishing its validity as an imaging tool. Also, standardized definitions of gray-scale and power Doppler ultrasonography findings in different age groups of children is still lacking. Nonetheless, ultrasound is a readily accessible imaging modality that is well tolerated by children. It also allows physicians to perform a …

Quality Of Icu Discharge Summaries Produced By Pediatric Residents: The Memorial Health University Medical Center Experience, Jessica M. Lee, James Ryden, Emma Meehan, Eric Shaw, Mary C. Lytle, Andrew Stack, Ashley Shearman

HCA Healthcare Journal of Medicine

Background

Discharging intensive care unit (ICU) patients directly home is becoming more common. High-quality ICU discharge summaries are crucial in the transition of patient care. Currently, at Memorial Health University Medical Center (MHUMC), there exists no standardized ICU discharge summary template or consistency when discharge documentation is completed. Investigators evaluated the timeliness and completeness of ICU discharge summaries at MHUMC produced by pediatric residents.

Methods

A single-center retrospective chart review of pediatric patients discharged directly from a 10-bed Pediatric ICU to home was conducted. Charts were evaluated pre- and post-intervention. The intervention included the implementation of a standardized ICU discharge …

Gender Dysphoria In Adolescents With Ehlers-Danlos Syndrome., Jordan T. Jones, William R. Black, Christine Moser, Eric T. Rush, Lindsey Malloy-Walton

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: Ehlers-Danlos Syndrome represents a family of heritable connective tissue disorders that include joint hypermobility, tissue fragility, and skin hyperextensibility. Ehlers-Danlos Syndrome presents with clinical sequela across multiple body systems that require multidisciplinary care. Little is known about adolescents with Ehlers-Danlos Syndrome who are transgender and gender diverse. To date, there have been no reports of transgender and gender diverse youth in pediatric patients with Ehlers-Danlos Syndrome. The objective of this study was to characterize transgender and gender diverse adolescents with Ehlers-Danlos Syndrome seen in a pediatric multidisciplinary specialty clinic.

METHODS: A retrospective chart review was performed and it was …

Transplantation In Pediatrics Liver Failure Associated With Acute Hepatitis Of Unknown Etiology, Afid B. Putra, Agi S. Putranto, Muftah Risyaldi, Luthfian A. Nurachman

The New Ropanasuri Journal of Surgery

Introduction. On 5^th April 2022, some cases of severe acute hepatitis of unknown etiology in children were reported in the United Kingdom. Since then, the number has increased rapidly, with 650 probable cases identified worldwide. This review focuses on available information about managing acute liver failure (ALF) in pediatrics with acute hepatitis of unknown etiology through the perspective of hepatobiliary surgery.

Method. A literature review proceeded on some databases, namely PubMed and Google Scholar. Epidemiological data and technical policy were obtained from World Health Organization and some government institutions.

Results. Severe acute hepatitis can progressively develop into acute liver …

The Importance Of Pediatric Provider Awareness Of Social Determinants Of Health And The Impact On Health Outcomes: An Integrative Review, Whitney Lenelle Dowd

Doctoral Dissertations and Projects

Social determinants of health have become a global concern over the past several years. Efforts to reduce negative health outcomes related to social determinants of health are of high priority. Awareness of this issue by providers, especially pediatric providers, must be considered to help combat this major concern. A researcher seeks through an integrative review to determine provider perspective on social determinants of health, impact of social determinants of health on outcomes, and ways of integrating social determinants into prescriptive practice. The integrative review will inform stakeholders about the importance of pediatric provider assessment of social determinants of health and …

Efficacy And Safety Of Fecal Microbiota Transplantation In Treatment Of Clostridioides Difficile Infection Among Pediatric Patients: A Systematic Review And Meta-Analysis, Kyaw Min Tun, Mark Hsu, Kavita Batra, Chun-Han Lo, Tooba Laeeq, Tahne Vongsavath, Salman Mohammed, Annie S. Hong Md

Internal Medicine Faculty Publications

Background and Aims: Cases of Clostridioides difficile infection have been rising among the pediatric and adolescent population. Fecal microbiota transplantation (FMT) has emerged as an alternative therapy for recurrent C. difficile infection. We aim to perform the first systematic review and meta-analysis investigating the safety and efficacy of fecal microbiota transplantation for C. difficile infection in children and adolescents. Methods: A literature search was performed using variations of the keywords “pediatrics”, “C. difficile infection”, and “fecal microbiota transplantation” in PubMed, EMBASE, CINAHL, Cochrane, and Google Scholar from inception to 30 June 2022. The resulting 575 articles were independently screened by …

Screening For Maternal Postpartum Depression In The Pediatric Primary Care Setting: An Educational Project, Mischelle M. Young, Dr. Robert Cornette, Dr. Lisa Padgett

Graduate Publications and Other Selected Works - Doctor of Nursing Practice (DNP)

Abstract

The birth of a baby can bring about an array of powerful emotions that range from joy and excitement to feelings of anxiety, worry, and depression. A majority of mothers experience postpartum baby blues which normally begins 2-3 days after delivery and can last for up to 2-3 weeks, but some mothers experience a more severe form known as postpartum depression (PPD). PPD can be mistaken for baby blues at first, but the signs and symptoms do not diminish and can continue to worsen. Postpartum depression signs and symptoms include withdrawing from friends and family, severe mood swings, excessive …

The Experiences Of Children With Neurological Conditions And Families, Charmaine Alexis Pasion, Jazminne Orozco Arteaga

Fall 2022 Virtual OTD Capstone Symposium

Children with chronic neurological conditions and their families experience various challenges that impact their quality of life and occupational participation as they reintegrate back into their communities (Dumas & Grajo, 2021; Taib et al., 2021). However, rehabilitation for children with chronic neurological conditions focuses on addressing functional impairments and self-care activities rather than transitioning home (Diener et al., 2021). Therefore, children and their families are in need of resources and interventions to address their occupational impact as they return to their occupations (Diener et al., 2021). This capstone research study explored the lived experiences of children with chronic neurological conditions …

Decreasing Pain In Pediatric Patients During Intravenous Catheter Insertions On The Pediatric Inpatient Surgery Unit, Breonna Scott, Robert Cornette, Tammy Childers

Graduate Publications and Other Selected Works - Doctor of Nursing Practice (DNP)

Abstract

As healthcare in the United States transforms, the voice of advocacy for pediatric patients is also evolving. The act of inserting a peripheral intravenous (IV) catheter for medical care of a pediatric patient is one of the most common invasive procedures in the healthcare industry. However, the preventable pain accompanying such a common procedure is often overlooked. Pediatric patients are different than adults due to the lack of physiological and psychological development. When a peripheral intravenous catheter is inserted without pain prevention interventions, there are long-term and short-term consequences for the patient and family. In turn, there are many …

Development And Use Of A Survey Tool To Prioritize And Catalyze Change Surrounding Faculty Wellness In A Department Of Pediatrics, Sarah Rhoads, Alison Riese, Mohammed Faizan, Lloyd Feit, Shuba Kamath, Albert Ross, Katherine Mason

Journal of Wellness

Introduction: Physician wellness is an important factor in the delivery of safe, effective and humanistic patient care. There is compelling data describing the widespread prevalence of physician burnout and its subsequent adverse impact on patient care, healthcare costs, and relationships. Initiatives to improve wellness are necessary to maintain the healthcare work force as well as to ensure high-quality care. This project investigated faculty physicians’ attitudes and priorities regarding physician wellness within the department of Pediatrics at a single-center academic institution.

Methods: A survey was created and distributed via e-mail to all faculty physicians employed within the Department of Pediatrics in …

Evaluation Of Pharmaceutically Compounded Oral Caffeine On The Impact Of Medication Adherence And Risk Of Readmission Among Preterm Neonates: A Single-Center Quasi-Experimental Study, Gul Ambreen, Manoj Kumar, Amin Ali, Syed Akbar Ali Shah, Syed Muzaffar Saleem, Ayesha Tahir, Muhammad Sohail Salat, Muhammad Shahzad Aslam, Kashif Hussain

Department of Biological & Biomedical Sciences

Background: Caffeine is available in an ampoule, used via parenteral and enteral routes in preterm neonates to treat apnea of prematurity (AOP) in neonates of gestational age ≥ 35-40 weeks. A longer duration of therapy has a higher risk of medication non-adherence due to higher costs and inappropriate dosage forms. Pharmaceutically compounded oral caffeine (PCC) could be an appropriate alternate dosage form. The researchers aimed to determine the impact of PCC on medication-related factors influencing medication adherence (MA) and the frequency of hospital readmission with apnea (HRA) in preterm neonates.
Methods: We conducted a single-center quasi-experimental study for this quality …

Improving The Accuracy Of Interactive Voice Response (Ivr) Technology For Pediatric Experience Scores, Elizabeth Spaargaren Ms, Mph, Cpxp, Abigail Kozak Mba, Cpxp, Cara Herbener Cpxp, Barbara Lawlor Burke Ma, Cpxp

Patient Experience Journal

The increased use of interactive voice response (IVR) in assessing patient and family experience should be paired with evidence-based practices on how to obtain the most accurate information via this survey mode. We added a brief clarification sentence of the survey scale at the start of the IVR call to improve our experience data both qualitatively and quantitatively. Our setting was an urban pediatric hospital. We gathered lived experiences from our patients, families, and providers to understand and design a change to the IVR survey mode that would reduce survey inaccuracies. Outcome measures were assessed by baseline measurement and post-intervention …

The Impact Of Follow-Up Calls After A Pediatric Emergency Department Visit, Joseph R. Mijares Iii, Sephora Morrison

Patient Experience Journal

Pediatric emergency department (ED) visits can be a stressful time for patients and their caregivers. This high stress environment can lead to questions and needed clarifications post-discharge. We implemented a post-discharge callback system to resolve these concerns for a focused subset of patients who historically have provided the most negative comment feedback on ED patient experience surveys. We hypothesized that comment types would shift to more positive than negative and the themes of the comments received would change. We developed a discharge callback process that focused on patients who were triaged as ESI level 4 during their emergency department visit. …

Children’S Experiences Of Hospitalization Over Time: An Evaluation Of Using Poetry And Creative Writing By Children To Assess Their Experiences Of Hospitalization, David Wood

Patient Experience Journal

This article explores children’s experiences of hospital admissions through their poetry and creative writing and assesses the validity of this medium compared to other methods of evaluation. Pediatric patient experiences of hospital and their effects on children have been studied in various ways and there have been stepwise changes throughout the past century, matching the overall changes of medical care from paternalistic to patient centered. 17 poems were analyzed from children aged 6-13 years old (median 10) for recurrent themes whilst admitted to a large tertiary hospital in the north of England. Children frequently wrote about attacks on their senses, …

Symptom Relief And Quality Of Life In Autistic Children Using Medical Cannabis: A Secondary Analysis, Wendy J. Ross, Md, Faap, Jennie Ryan, Madalene Zale, Alexander Fossi, Mph

Department of Psychiatry and Human Behavior Posters

Objectives

• This study aimed to examine the experiences of parents and caregivers of autistic children who used medical cannabis (MMJ) for the treatment of core symptoms or co-occurring conditions
• Considered priorities and outcomes of medical cannabis use, including: 1) Quality of life (QoL) effects; 2) Symptoms of interest; 3) Symptoms of co-occurring conditions

A Review Of Ferric Citrate Clinical Studies, And The Rationale And Design Of The Ferric Citrate And Chronic Kidney Disease In Children (Fit4kid) Trial., Mark R. Hanudel, Marciana L. Laster, Anthony A. Portale, Aditi Dokras, Raymond P. Quigley, German A Lozano Guzman, Joshua J. Zaritsky, Nicole A. Hayde, Frederick J. Kaskel, Mark M. Mitsnefes, Jorge A. Ramirez, Peace D. Imani, Poyyapakkam R. Srivaths, Amy J. Kogon, Michelle R. Denburg, Tom D. Blydt-Hansen, Loretta Z. Reyes, Larry A. Greenbaum, Darcy K. Weidemann, Bradley A. Warady, David A. Elashoff, Susan R. Mendley, Tamara Isakova, Isidro B. Salusky

Manuscripts, Articles, Book Chapters and Other Papers

Pediatric chronic kidney disease (CKD) is characterized by many co-morbidities, including impaired growth and development, CKD-mineral and bone disorder, anemia, dysregulated iron metabolism, and cardiovascular disease. In pediatric CKD cohorts, higher circulating concentrations of fibroblast growth factor 23 (FGF23) are associated with some of these adverse clinical outcomes, including CKD progression and left ventricular hypertrophy. It is hypothesized that lowering FGF23 levels will reduce the risk of these events and improve clinical outcomes. Reducing FGF23 levels in CKD may be accomplished by targeting two key stimuli of FGF23 production-dietary phosphate absorption and iron deficiency. Ferric citrate is approved for use …

Prevalence Of Metabolic Syndrome In School-Aged Obese Children, Maha A. Tawfik, Mohamed A Abdo Al-Fiqi, Soheir S. Abou El-Ella, Zeinab S. Abou Zouna

Menoufia Medical Journal

Objective To evaluate the prevalence of metabolic syndrome (MS) in a group of school-aged obese children of both sexes. Background Data about MS in children are limited in Egypt as the prevalence and magnitude of obesity among school-aged children has been increasing dramatically. We examined the effect of varying degrees of obesity on the prevalence of the MS. Patients and methods This cross-sectional study was conducted on obese children (BMI ≥ 95^th percentile), aged 6–16 years. Detailed history taking with family pedigree; complete systemic examination; anthropometric measurements, including weight (kg) on Z score, height (m) on Z score, waist …

Anthropometry Of The Lower Zone Of The Face In Preschool-Aged Children, Assem M. Salama, Maha A. Tawfik, Naglaa F. Barseem

Menoufia Medical Journal

Objective To assess anthropometry of the lower zone of the face (philtrum length, philtrum width, intercommissural distance, and lower lip to chin length) in preschool-aged children in Menoufia Governorate. Background All health personnel having a responsibility toward the care of children should be sufficiently familiar with normal patterns of growth and milestones so that they can recognize overt deviations from the normal range as early as possible, for underlying disorders to be identified and given appropriate attention. Patients and methods This was a cross-sectional study conducted on 516 Egyptian apparently healthy preschool children of both sexes (between 3 and 6 …

Study Of Serum Albumin Level In Critically Ill Children Admitted To Icus, Dina M M. Ali, Maha A. Tawfik, Noran T. Aboelkhair, Zeinab S Abou Zouna

Menoufia Medical Journal

Objectives The aim of the current study was to study serum albumin level in critically ill children admitted to the pediatric ICU in Menoufia University hospital and its relation to the outcome. Background Hypoalbuminemia is a common feature in critically ill children in pediatric ICUs and is associated with a poor outcome. Patients and methods A cross-sectional study was conducted on 118 critically ill children from January 2021 to December 2021. All patients in the present study were subjected to detailed history, physical examination, and laboratory investigations. Pediatric Sequential Organ Failure Assessment (PSOFA), Pediatric Risk of Mortality III (PRISM III), …

Prevalence Of Helicobacter Pylori Infection Among Children With Nephrotic Syndrome, Fahima M. Hassan, Heba B Abd Elsalam, Mahmoud A. E.M. A. Eldaher, Nagwan Y. Saleh

Menoufia Medical Journal

Objective To evaluate the prevalence of Helicobacter pylori infection among children diagnosed as having nephrotic syndrome (NS). Background NS is primarily a pediatric disorder and is 15 times more common in children than adults. H. pylori colonizes more than 50% of people worldwide. Patients and methods This prospective study was conducted on 50 children with NS admitted and followed up in the Pediatric Nephrology Unit at Menoufia University Hospital. They were screened for H. pylori by urea breath test, stool analysis (Rapid HpSA test), and serum H. pylori antibodies. The included patients were divided into two groups regarding clinical manifestations …

Clinical Assessment And Follow-Up Of School-Aged Diabetic Children, Kamel Gomaa, Maha A. Tawfik, Soheir S. A. El-Ella, Zeinab S. Abouzouna

Menoufia Medical Journal

Objective Clinical assessment and follow-up in school-aged diabetic children. Background Diabetes mellitus requires continuous medical care, patient self-management, education, and support to prevent acute complications and to reduce long-term complications. Patients and methods This descriptive study was conducted on 110 diabetic Egyptian children. All patients were subjected to detailed history taking, complete general examination including anthropometric measurements and laboratory investigations including estimation of fasting blood glucose level (mg/dl), postprandial blood glucose level (mg/dl), glycosylated hemoglobin (HbA1c%), lipid profile (cholesterol, low-density lipoprotein, and triglyceride), microalbumin in urine, and thyroid function (thyroid-stimulating hormone and FT4). Results The mean age of the studied …

Evaluation Of Noninvasive Tests For Diagnosis Of Helicobacter Pylori Infection In Hemodialysis Pediatric Patients, Alia E. El-Sayad Oqdah, Fahima M. Hassan, Heba B Abdel Salam, Nagwan Y. Saleh

Menoufia Medical Journal

Background Patients on hemodialysis often have gastrointestinal complications; however, it is unclear whether Helicobacter pylori infection is more prevalent in these patients. Objective To determine the incidence of H. pylori infection in pediatric patients with chronic kidney disease on regular hemodialysis and to investigate the diagnostic value of noninvasive tests [urea-breath test (UBT), stool-antigen test (SAT), and serology] in diagnosing H. pylori infection in hemodialysis patients. Patients and methods An analytical cross-sectional study was carried out on 62 children with the end-stage renal disease treated by regular-maintenance hemodialysis in the Nephrology Unit in Pediatric Department, Menoufia University Hospital, to determine …

Serum Levels Of Homocysteine And Interleukin-6 In Children With Idiopathic Epilepsy In Menoufia University Hospital, Ahmed T. Mahmoud, Maha A. El-Bassuoni, Mohamed S. El Haroun, Shaimaa Ibrahim Zalat

Menoufia Medical Journal

Background Epileptic seizures are due to excessive, abnormal, or synchronous signaling, or depolarization, in the brain cells. Homocysteine (Hcy) and interleukin-6 (IL-6) are a thiol metabolite derived from the demethylation of methionine. It is widely known that folate deficiency takes place in a few epileptic patients taking antiepileptic drugs (AEDs), causing decreased remethylating or transculturation of Hcy. The effect of systemic inflammatory responses on generalized motor seizures in pediatric patients with epilepsy needs to be evaluated. Objectives To measure serum levels of Hcy and IL-6 in children with idiopathic epilepsy in relation to their clinical findings. Patients and methods A …

Neuroglobin As A Novel Biomarker In Childhood Seizures, Heba B. Abd Elsalam, Sameh A. Abd Elnaby, Sara M. Eldeeb, Yasmeen K E. El-Fiky

Menoufia Medical Journal

Objectives The aim of this study is to investigate the possible role of neuroglobin as a novel biomarker in children with febrile seizures and epileptic children. Background Neuroglobin is a new globin member that is highly expressed in the central and peripheral nervous system. Patients and methods This case–control study has been conducted on 75 children, divided into three groups: group I included children with simple febrile convulsions, group II included children with newly diagnosed idiopathic epilepsy, and group III included healthy children selected as controls. Serum neuroglobin assay, complete blood count, C-reactive protein level, random blood sugar, serum electrolytes, …

Role Of Pancreatic Stone Protein In Critically Ill Children, Mina L. Hana, Mona S E. Habieb, Muhammad S. El-Mekkawy, Nagwan Y. Saleh

Menoufia Medical Journal

Objective To assess the role of pancreatic stone protein (PSP) in evaluation of critically ill children admitted to a pediatric intensive care unit (PICU). Background PSP was suggested to be a promising biomarker for determining critical illness severity among pediatric children. Patients and methods This prospective observational study was conducted on 75 critically ill children and 15 healthy controls. Serum PSP was measured in patients within 24 h of PICU admission and on healthy controls with commercially available enzyme-linked immunosorbent assay kits. Results Serum level of PSP was significantly elevated among patients than controls (P < 0.001). The most common cause of PICU admission was respiratory illness (44%). Besides, C-reactive protein, white blood cell count, and absolute neutrophil count were significantly elevated among patients compared with controls (P = 0.001, 0.005, …

Reln Gene (Rs 2229864) Polymorphismas Genetic Risk Factor In Egyptian Children With Autism Spectrum Disorders, Doaa Elsayed Abo Elfetoh, Nahla M. Said Abdelhady, Sally M. El-Hefnawy, Sameh A Abd El Naby

Menoufia Medical Journal

Background Reelin (RELN) is a large secreted extracellular matrix glycoprotein that regulates processes of neuronal migration and positioning in the developing brain by controlling cell–cell interactions. RELN has been suggested to be implicated in pathogenesis of several brain diseases. Autism is a developmental disorder that appears in the first 3 years of life, and affects the brain's normal development of social and communication skills. Aim The purpose of this case–controlled study was to explore the linkage between RELN gene polymorphism (rs2229864) with autism. Patients and methods In total, 180 Egyptian children were enrolled in this study, including 120 children with …

Effect Of Tmprss6 Rs855791 (T>C) Polymorphism On Pathophysiology Of Iron-Deficiency Anemia, Dinesh Pandey, Jyoti Singh, Naresh Bajaj, Sanjay Kumar Pandey, Shalini Kunder, Sudhakar Dwivedi, Sweta Pandey, Vinit Singh Baghel

Menoufia Medical Journal

Background The TMPRSS6 (Transmembrane Serine Protease 6) gene is found on chromosome 22. TMPRSS6 is a protein-coding gene. Iron absorption and metabolism in the body is controlled by matripase-2 enzyme, which is encoded by TMPRSS6 gene. Objectives TMPRSS6 rs855791 polymorphism was investigated for its effect on serum iron levels of patients with iron-deficiency anemia. Patients and methods A tertiary referral hospital served as the study setting. The complete blood count was analyzed using an automated five-part hemtoanalyzer. Enzyme-linked immunosorbent assay (ELISA) was used to analyze ferritin in serum. Restriction fragment length polymorphism PCR-RFLP was used to genotype TMPRSS6rs855791 C>T …

Study Of Klotho Polymorphism In Egyptian Children With Chronic Kidney Disease On Regular Hemodialysis: Single-Center Study, Fatma A. Radwan, Maha A. Tawfik, Mohamed Sh. Elharoun

Menoufia Medical Journal

Background Secondary hyperparathyroidism and bone fractures are common complications of chronic kidney diseases (CKD). Klotho (KL) protein is a coreceptor for fibroblast growth factor 23 and hence is involved in maintaining endocrine-system homeostasis and reduces cell death. Furthermore, KL is a valuable regulating factor in calcium/phosphate (Ca/P) metabolism. Objective To identify the KL polymorphism rs9536314 and its relationship with Ca/P metabolism and parathyroid-hormone (PTH) concentrations in children on regular hemodialysis (HD). Patients and methods A cross-sectional study was conducted for 6 months, from December 2020 to June 2021, on 50 pediatric patients with CKD on regular HD and an exact …

A Methodological And Clinical Approach To Measured Energy Expenditure In The Critically Ill Pediatric Patient., Jaime Silva-Gburek, Paola Hong Zhu, Marwa Mansour, David Walding, Jorge A. Coss-Bu

Manuscripts, Articles, Book Chapters and Other Papers

The metabolic response to injury and stress is characterized initially by a decreased energy expenditure (Ebb phase) followed by an increased metabolic expenditure (Flow phase). Indirect calorimetry is a methodology utilized to measure energy expenditure and substrate utilization by measuring gas exchange in exhaled air and urinary nitrogen. The use of indirect calorimetry in critically ill patients requires precise equipment to obtain accurate measurements. The most recent guidelines suggested that measured energy expenditure by indirect calorimetry be used to determine energy requirements. This article reviews the methodological and clinical use of indirect calorimetry in critically ill pediatric patients.

Conference Proceedings: Select Abstracts Presented At Advocate Aurora Scientific Day 2022

Journal of Patient-Centered Research and Reviews

The abstracts published in this supplement were presented at the 48th annual Advocate Aurora Scientific Day on May 25, 2022. This scholarly symposium provides a closed forum for sharing preliminary results from research studies conducted by faculty physicians and nurses, fellows, residents, scientists, and other health professionals associated with U.S. Midwest-based health system Advocate Aurora Health, publisher of the Journal of Patient-Centered Research and Reviews.