Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

PDF

2021

SARS-CoV-2

Revista de la Facultad de Medicina Humana

Articles 1 - 4 of 4

Full-Text Articles in Medicine and Health Sciences

Clinical Epidemiological Characteristics Of Patients Diagnosed With Sars-Cov-2. Hospital I Florencia De Mora Essalud – La Libertad, 2020, Yeny Tejada López, Evelyn Del Socorro Goicochea Ríos, Olga Y. Guzmán Aybar Oct 2021

Clinical Epidemiological Characteristics Of Patients Diagnosed With Sars-Cov-2. Hospital I Florencia De Mora Essalud – La Libertad, 2020, Yeny Tejada López, Evelyn Del Socorro Goicochea Ríos, Olga Y. Guzmán Aybar

Revista de la Facultad de Medicina Humana

Introduction: the SARS-CoV-2 pandemic affected a large part of the population of La Libertad, among them, the population of Florencia de Mora whose hospital played an important role in the care of patients diagnosed with COVID-19. Objective: to determine the epidemiological clinical characteristics of patients diagnosed with SARS-CoV-2 treated at the care center. Methods: Retrospective observational descriptive study, with a population of 2622 patients treated in the COVID-19 triage, taking into account the molecular test and the rapid serology test for the detection of SARS-CoV-2. Results: SARS-CoV-2 was detected in 74.90% (1155) of patients. The months with the highest number …


Molecular Basis Of Covid-19 Pathogenesis And In Silico Studies Of Potential Pharmacological Treatment, Eduardo Lam Cabanillas, Anthony León Risco, Kevyn León Risco, Gaby Llamo Hoyos, Rosa López Zavaleta, Estefanía Luzuriaga Tirado, Alex Mendoza Blas, Juan Huamán Saavedra Mar 2021

Molecular Basis Of Covid-19 Pathogenesis And In Silico Studies Of Potential Pharmacological Treatment, Eduardo Lam Cabanillas, Anthony León Risco, Kevyn León Risco, Gaby Llamo Hoyos, Rosa López Zavaleta, Estefanía Luzuriaga Tirado, Alex Mendoza Blas, Juan Huamán Saavedra

Revista de la Facultad de Medicina Humana

COVID-19 is a disease caused by SARS-CoV-2, a virus that represents a serious threat to global health. The objective of the article is to deepen into the structure of the structural and non-structural proteins of SARS-CoV-2 and their role during the infection of its target cells; also to propose molecules from in silico studies that inhibit proteins of the viral cycle for potential pharmacological treatments. The SARS-CoV-2 genome has ORFs that encode sixteen non-structural proteins (Nsp1-16), four structural proteins (Spike, Envelope, Membrane, and Nucleocapsid), and nine accessory proteins; that fulfill various functions in the entry of the virus and its …


Neurological Damage In Sars-Cov-2 Infections, Jorge Vega-Fernández, Danny Suclupe-Campos, Franklin Aguilar-Gamboa Mar 2021

Neurological Damage In Sars-Cov-2 Infections, Jorge Vega-Fernández, Danny Suclupe-Campos, Franklin Aguilar-Gamboa

Revista de la Facultad de Medicina Humana

The current Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has severely impacted the economy and health care system in more than 180 countries around the world in an unprecedented event, which since its inception has resulted in countless case reports focusing on the potentially fatal systemic and respiratory manifestations of the disease. However, the full extent of possible neurological manifestations caused by this new virus is not yet known. Understanding the interaction of SARS-CoV-2 with the nervous system is essential to assessing likely short- and long-term pathologic consequences. This review seeks to gather and discuss evidence on the occurrence …


The Covid-19 Pandemic: The Importance Of Being Alert To Zoonoses., Manuel E. Cortés Mar 2021

The Covid-19 Pandemic: The Importance Of Being Alert To Zoonoses., Manuel E. Cortés

Revista de la Facultad de Medicina Humana

The pandemic of Coronavirus Disease - 2019 (COVID) has produced hundreds of thousands of deaths and millions of infected people worldwide, with the consequent collapse of health systems. SARS-CoV-2, the coronavirus causing COVID-19, is a pathogen with a zoonotic origin. The objective of this article is to highlight the importance of being alert to zoonoses, with special reference to COVID-19. First, the general chronology of the COVID-19 pandemic is described, then the characteristics of the coronaviruses are described in detail, especially regarding those of SARS-CoV-2. Subsequently, the One Health concept is highlighted as an appropriate approach to face this zoonosis …