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Full-Text Articles in Medicine and Health Sciences

Idiopathic Condylar Resorption: The Current Understanding In Diagnosis And Treatment, Andrew L. Young Jul 2017

Idiopathic Condylar Resorption: The Current Understanding In Diagnosis And Treatment, Andrew L. Young

Andrew L. Young

Idiopathic condylar resorption (ICR) is a condition with no known cause, which manifests as progressive malocclusion, esthetic changes, and often pain. Cone‑beam computed tomography and magnetic resonance imaging are the most valuable imaging methods for diagnosis and tracking, compared to the less complete and more distorted images provided by panoramic radiographs, and the higher radiation of 99mtechnetium‑methylene diphosphonate. ICR has findings that overlap with osteoarthritis, inflammatory arthritis, physiologic resorption/remodeling, congenital disorders affecting the mandible, requiring thorough image analysis, physical examination, and history‑taking. Correct diagnosis and determination of whether the ICR is active or inactive are essential when orthodontic or prosthodontic …


Idiopathic Condylar Resorption: The Current Understanding In Diagnosis And Treatment, Andrew L. Young May 2017

Idiopathic Condylar Resorption: The Current Understanding In Diagnosis And Treatment, Andrew L. Young

All Dugoni School of Dentistry Faculty Articles

Idiopathic condylar resorption (ICR) is a condition with no known cause, which manifests as progressive malocclusion, esthetic changes, and often pain. Cone‑beam computed tomography and magnetic resonance imaging are the most valuable imaging methods for diagnosis and tracking, compared to the less complete and more distorted images provided by panoramic radiographs, and the higher radiation of 99mtechnetium‑methylene diphosphonate. ICR has findings that overlap with osteoarthritis, inflammatory arthritis, physiologic resorption/remodeling, congenital disorders affecting the mandible, requiring thorough image analysis, physical examination, and history‑taking. Correct diagnosis and determination of whether the ICR is active or inactive are essential when orthodontic or …


Expression Of Mmp-13 In Human Temporomandibular Joint Disc Derangement And Osteoarthritis, Juliano Henrique Perotto, Flavio Camejo, Andrea Doetzer, Luis Eduardo Almeida, Marina Azevedo, Marcia Olandoski Jan 2017

Expression Of Mmp-13 In Human Temporomandibular Joint Disc Derangement And Osteoarthritis, Juliano Henrique Perotto, Flavio Camejo, Andrea Doetzer, Luis Eduardo Almeida, Marina Azevedo, Marcia Olandoski

School of Dentistry Faculty Research and Publications

Objective: MMP-13 performs digestion of collagen, which is a primary component of the temporomandibular joint (TMJ) articular disc. This study evaluated the expression of MMP-13 in patients with anterior disc displacement with (ADDwR) and without reduction (ADDwoR), and in the presence of TMJ osteoarthrosis.

Methods: Thirty-nine human temporomandibular joint disc samples were collected and divided in two ways: ADDwR (21 samples), ADDwoR (10 samples), and a control group (8 samples); and with osteoarthrosis (10 samples) and without osteoarthrosis (29 samples). Immunostaining of the TMJ discs was statistically compared between the groups.

Results: There was no statistically significant difference for the …