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Full-Text Articles in Medicine and Health Sciences

Heterogeneity Of Clonogenic Cells In Acute Myeloblastic Leukemia., Kert D. Sabbath, Edward D. Ball, Peter Larcom, Roger B. Davis, James D. Griffin Feb 1985

Heterogeneity Of Clonogenic Cells In Acute Myeloblastic Leukemia., Kert D. Sabbath, Edward D. Ball, Peter Larcom, Roger B. Davis, James D. Griffin

Dartmouth Scholarship

The expression of differentiation-associated surface antigens by the clonogenic leukemic cells from 20 patients with acute myeloblastic leukemia (AML) was studied with a panel of seven cytotoxic monoclonal antibodies (anti-Ia, -MY9, -PM-81, -AML-2-23, -Mol, -Mo2, and -MY3). The surface antigen phenotypes of the clonogenic cells were compared with the phenotypes of the whole leukemic cell population, and with the phenotypes of normal hematopoietic progenitor cells. In each case the clonogenic leukemic cells were found within a distinct subpopulation that was less "differentiated" than the total cell population. Clonogenic leukemic cells from different patients could be divided into three phenotype groups. …


Comparative Study Of Pituitary-Thyroid Hormone Economy In Fasting And Hypothyroid Rats., Donald L. St Germain, Valerie A. Galton Feb 1985

Comparative Study Of Pituitary-Thyroid Hormone Economy In Fasting And Hypothyroid Rats., Donald L. St Germain, Valerie A. Galton

Dartmouth Scholarship

Starvation in laboratory rodents results in significant alterations in thyroid hormone economy characterized by decreased circulating levels of thyroxine (T4) and 3,5,3'-triiodothyronine (T3) and a decline in serum thyrotropin (TSH) concentration. To investigate this apparent paradox, we have compared in fasted and hypothyroid animals the intracellular parameters mediating thyroid hormone action in the anterior pituitary gland. In vitro saturation analysis combined with quantitation of nuclear T3 content by radioimmunoassay allowed for characterization of pituitary nuclear T3 receptors and estimation of the endogenous fractional receptor occupancy. In rats, thyroidectomized 4 wk earlier, the 10-fold increase in serum TSH levels and decline …


Harris County Medical Society Ellen Durckel Interviewing Dr. Mylie E. Durham, Jr. March, 1985, Mylie E. Durham Jr (1919-1991) Jan 1985

Harris County Medical Society Ellen Durckel Interviewing Dr. Mylie E. Durham, Jr. March, 1985, Mylie E. Durham Jr (1919-1991)

Mylie E. Durham, Jr., MD Papers

These documents are an interview done by the Harris County Medical Society by Ellen Durckel. Within the Q&A, he discusses his early childhood, memories with his father, influences of his mother, early marriage, and military history. See more at Mylie E. Durham, Jr., MD Papersand its finding aid.


Summary Of Interview With Doctor Mylie E. Durham, Jr., Md, Mylie E. Durham Jr (1919-1991) Jan 1985

Summary Of Interview With Doctor Mylie E. Durham, Jr., Md, Mylie E. Durham Jr (1919-1991)

Mylie E. Durham, Jr., MD Papers

These documentsare biographical information topics around his family, military history, education, and influential figures. See more at Mylie E. Durham, Jr., MD Papersand its finding aid.


March 1985 Biography Information- Mylie E. Durham Jr., Md, Mylie E. Durham Jr (1919-1991) Jan 1985

March 1985 Biography Information- Mylie E. Durham Jr., Md, Mylie E. Durham Jr (1919-1991)

Mylie E. Durham, Jr., MD Papers

These documents are biographical information in relations to early life, education, and professional activities. See more at Mylie E. Durham, Jr., MD Papersand its finding aid.


Summary Of Interview With Doctor Mylie E. Durham, Jr., Md, Mylie E. Durham Jr (1919-1991) Jan 1985

Summary Of Interview With Doctor Mylie E. Durham, Jr., Md, Mylie E. Durham Jr (1919-1991)

Mylie E. Durham, Jr., MD Papers

These documentsare a summary of an interview with the questions directed by Doctor Roger Bulgar. The Q&A centers around his professional life and what motives him to be a doctor. See more at Mylie E. Durham, Jr., MD Papersand its finding aid.


Index Of Interviews With Mylie E. Durham Jr., Md, Mylie E. Durham Jr (1919-1991) Jan 1985

Index Of Interviews With Mylie E. Durham Jr., Md, Mylie E. Durham Jr (1919-1991)

Mylie E. Durham, Jr., MD Papers

These documents are an index for the summarized transcripts for the interview with Dr. Mylie E. Durham, Jr. See more at Mylie E. Durham, Jr., MD Papersand its finding aid.


Harris County Medical Society Ellen Durckel Interviewing Dr. Mylie E. Durham, Jr. (Continued), Mylie E. Durham Jr (1919-1991) Jan 1985

Harris County Medical Society Ellen Durckel Interviewing Dr. Mylie E. Durham, Jr. (Continued), Mylie E. Durham Jr (1919-1991)

Mylie E. Durham, Jr., MD Papers

In this Q&A, he discusses his early career, his medical focuses on military history, second marriage, his work in Houston, his relationship with George Herman, and how the medical field has become colder and more professional before. See more at Mylie E. Durham, Jr., MD Papersand its finding aid.


Harris County Medical Society Ellen Durckel Interviewing Interviewing Dr. Mylie E. Durham, Jr. (Continued), Mylie E. Durham Jr (1919-1991) Jan 1985

Harris County Medical Society Ellen Durckel Interviewing Interviewing Dr. Mylie E. Durham, Jr. (Continued), Mylie E. Durham Jr (1919-1991)

Mylie E. Durham, Jr., MD Papers

In this Q&A, he discusses how the medical field has evolved into a big business, the changing of relationships between doctors and patients, what made him decide to be specialized in an area, the insurance has made the doctors overcharge for procedures, and what the role of a doctor is. See more at Mylie E. Durham, Jr., MD Papersand its finding aid.