Medicine and Health Sciences Commons^™

Air Pollution And Health: What The Georgia Physician Should Know, Pamela Meyer, David M. Mannino, Stephen Redd

David M. Mannino

No abstract provided.

Protection From Oxidative Stress–Induced Apoptosis In Cortical Neuronal Cultures By Iron Chelators Is Associated With Enhanced Dna Binding Of Hypoxia-Inducible Factor-1 And Atf-1/Creb And Increased Expression Of Glycolytic Enzymes, P21waf1/Cip1, And Erythropoietin, Kevin O'Donovan

Kevin O'Donovan

No abstract provided.

The Egr Family Of Transcription-Regulatory Factors: Progress At The Interface Of Molecular And Systems Neuroscience, Kevin O'Donovan

Kevin O'Donovan

No abstract provided.

Correlates Of Suicide Risk In Adolescent Inpatients Who Report Histories Of Childhood Abuse, Carlos M. Grilo, Charles A. Sanislow, Dwain C. Fehon, Deborah S. Lipschitz, Steve Martino, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

The study objective was to examine correlates of suicide risk in psychiatrically hospitalized adolescents with a reported history of childhood abuse. Predictors of suicide risk were examined in 74 subjects who reported a history of childhood abuse and 53 depressed subjects who did not report a history of childhood abuse. Subjects completed a battery of psychometrically well-established self-report instruments to assess childhood abuse, suicide risk, and internalizing and externalizing psychopathology. Correlational analyses showed that higher levels of depression, self-criticism, and hopelessness were significantly associated with suicide risk in both study groups and violence was significantly associated with suicide risk in …

A Novel Human Xenograft Model Of Inflammatory Breast Cancer, Mary L. Alpaugh, J. S. Tomlinson, Z. M. Shao, S. H. Barsky

Mary Alpaugh

Stem Cell Research: Licit Or Complicit?, M. Therese Lysaught

M. Therese Lysaught

No abstract provided.

Familial Cases Of Missing Mandibular Incisor: Three Case Presentations, W. L. Chai, W.C. Ngeow

Wei Cheong Ngeow

Hypodontia is the congenital absence of one or more teeth because of agenesis. The most commonly missing teeth are the third molars, the maxillary lateral incisors and the second premolars. Cases are presented of three patients with a missing mandibular incisor.

The Perception Of Spirituality And Its Manifestations In The Lives Of African American Male College Students, Adrienne Coleman

Adrienne Coleman

This study initiated in response to the lack of information on spirituality in African Americans and more specifically African American males. It is very important that spirituality be studied to make health educators knowledgeable about its overall nature. With awareness the health educators will be prepared to implement health promotion interventions that are appropriate and consistent with the beliefs of this subculture. The literature regarding this subject addressed many different aspects of spirituality. There was only a minute amount of information on African Americans and even less on African American males. Instead the literature search concentrated on areas such as: …

Phd Thesis (Doctorat De Spécialité): Université De Ouagadougou, 1999. Dr. Mamoudou H. Dicko. Purification Et Propriétés Physico-Chimiques Des Enzymes De Curculigo Pilosa, Gladiolus Klattianus Et Boscia Senegalensis Catalysant L'Hydrolyse Des Polysaccharides (Amidon Et Béta-Glucanes), Mamoudou H. Dicko Prof.

Pr. Mamoudou H. DICKO, PhD

The objective of this study was the research of novel and inexpensive sources of polysaccharides degrading enzymes such as amylases and glucanases from local plants in order to justify their biotechnological applications. The isolation of two l3-amylases and an endo-1,3-ß-D-glucanase was reached using common protein purification methods such as buffer extraction, ammonium sulfate fractionation, ionexchange and gel filtration chromatographies. The methods used were simple and easily reproducible, suggesting the possibilfty of large-scale production. ln the crude extract of Curculigo pilosa tuber, only ß-amylase was detected as starch degrading enzyme and its activity was approximately 282 Uig of fresh material. The …

Survival Versus Years Of Healthy Life; Which Is More Powerful As A Study Outcome?, Paula Diehr

Paula Diehr

Studies of interventions that are intended to improve patients' health are often evaluated with survival as the primary outcome, even when a measure adjusted for quality of survival, such as years of healthy life (YHL), would seem more appropriate. The purpose of this article is to determine whether studies based on survival are more or less powerful than studies based on YHL in clinical trials where either measure might be appropriate. We used data from the Cardiovascular Health Study (CHS) to estimate the sample size that would be needed in studies of 156 different health conditions, for the two outcome …

Clinicopathologic Study Of Odontogenic Keratocysts In Singapore And Malaysia, W.C. Ngeow, R. B. Zain, J. F. Yeo, W. L. Chai

Wei Cheong Ngeow

This was a retrospective study of odontogenic keratocysts in people from the Singapore-Malaysian region. The purpose of this study was to present the clinicopathologic features of odontogenic keratocysts in the Oriental population and to compare these data with those from other reported studies. Biopsy records from 1981 to 1992 of 61 cases of odontogenic keratocysts from patients in Malaysia and Singapore showed that 42.6% of patients were female and 57.4% of patients were male. Among patients with cysts, 75.4% were Chinese, 6.6% were Malays, 9.8% were Indians and 8.2% were other ethnic groups. The mean age of these patients was …

Serum Micronutrients Level In Selected Malaysian Indian Populations - Preliminary Findings, Rosnah Binti Zain, Shanmuhasuntharam P., Fukano H., Ikeda N., Razak L. A., Ghazali M. N., Yano M., Miyazaki H., Ito Y.

Prof. Dr. Rosnah Binti Zain

A pilot study in 1995 on 46 Malaysian had shown that mean serum levels of alpha carotene (AC), beta carotene (BC), retinol (Ret) and alpha-tocopherol (AT) in patients with oral cancer, leukoplakia or chewer’s mucosa were lower when compared to patients without lesion. The purpose of this study is to further investigate the serum levels of certain micronutrients in a selected group of Indians from estate population in Malaysia. Out of 561 subjects screened for oral cancer and/or precancer (OPC), blood samples were obtained from more than 300 subjects. Serum analysis for Ret, AT, Zeaxanthin/Lutein (Z/L), Cryptoxanthin (Cry), Lycophene (Lye), …

Periodontal Status And Treatment Needs Among Indian Estate Population, Ali T. T., Razak I. A., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

The aim of this study was to determine the periodontal status and treatment needs among the Indian estate population. The Community Periodontal Index of Treatment Needs was used to obtained clinical data on 208 Indian subjects residing in three estates in the state of Selangor. The prevalence of periodontal disease among the subjects was 100%. Less than 1% of the subjects had bleeding on probing as the highest CPITN score. About 97% of the subjects showed evidence of periodontal pocket of 4mm or more. Of these, half showed pocketing of 6mm or more. No statistically significant difference (p> 0.05) was …

Oral Mucosal Lesions In Malay Quid And Non-Quid Chewers In Kelantan, Raman R. A., Rahman Z. A. A., Rosnah Binti Zain, Samsuddin A. R., Razak I. A., Abdullah F., Venugopal I.

Prof. Dr. Rosnah Binti Zain

The Malaysian nationwide survey on oral mucosal lesions (OML) in 1993/94 showed a low prevalence of OML in particular oral cancer and precancer (OPC) among Malays as compared to the Indians and the Indigenous people of Sabah and Sarawak. A low prevalence of quid chewing habit was also noted in the Malays in that survey. The present study was conducted to investigate whether the low prevalence of OPC in the Malays was attributed to the low prevalence of quid users among the Malays and/or whether the quid contents used were different. Two examiners were trained prior to the survey. The …

Clinicopathologic Presentations Of 18 Cases Of Traumatic Granulomas, Rosnah Binti Zain, Ti L. S.

Prof. Dr. Rosnah Binti Zain

A retrospective study of 11 cases of traumatic granulomas was done. The objective of this study is to present the clinicopathological features of traumatic granulomas in some malaysian patients and to compare this data with data from other reported studies, which have been predominantly from Caucasian population. Biopsy records from 1985 to 1998 of 18 cases of traumatic granulomas were obtained. There were 13 male and 5 female patients. The granulomas occured in 38.9% Malay, 38.9% Chinese, 11.1% Indian and 11.1% other ethnic groups. The age of these patients range from 8 to 86 years, with mean of 41.9 ± …

Clinicopathologic Study Of Odontogenic Keratocysts In Singapore And Malaysia, Ngeow W. C., Rosnah Binti Zain, Yeo J. F., Chai W. L.

Prof. Dr. Rosnah Binti Zain

A retrospective study of odontogenic keratocysts in the Malaysia-Singapore region was done. The purpose of this study is to present the clinicopathological features of odontogenic keratocysts in the Oriental population and to compare the data with those from other reported studies. Biopsy records from 1981 to 1992 of 61 cases of odontogenic keratocysts in Malaysia and Singapore showed that there were 42.6% female and 57.4% male patients. The cysts occurred in 75.4% Chinese, 6.6% Malays, 9.8% Indian, and 8.2% other ethnic groups. The mean age of these patients was 26.98 ± 15.38 years with peak incidence in the second to …

Tenascin-C In Betel-Quid Associated Lesions, Rosnah Binti Zain, Fukano H., Ikeda N., Kudeken W., Shrestha P., Ghazali M. N., Takai Y., Mori M.

Prof. Dr. Rosnah Binti Zain

The expression of Tenascin-C, an adhesion modulating or anti- adhesive extracellular matrix protein, was evaluated in betel quid associated lesions of oral mucosa showing focal hyperkeratosis (n=15), dysplasia (n=15), oral submucous fibrosis (n=7) and oral squamous cell carcinoma (n=8). All the patients were chewers of betel quid containing betel leaves, areca nuts, lime and tobacco. The results obtained from this study were compared to similar lesions in smokers and non-quid users cited in the literature (Shrestha et al, Oral Oncol, 1994). An enhanced expression of TN-C was observed in epithelial connective tissue interface of quid associated hyperkeratotic and dyplastic mucosa. …

Median Mental Sinus In Twins, W.C. Ngeow, S. T. Ong

Wei Cheong Ngeow

Sinus on the chin can be the result of a chronic apical abscess due to pulp necrosis of a mandibular anterior tooth. The tooth is usually asymptomatic, and a dental cause is therefore not apparent to the patient or the unsuspecting clinician. Not infrequently, the patient may seek treatment from a dermatologist or general surgeon instead of a dentist. Excision and repair of the fistula may be carried out with subsequent breakdown because the dental pathology is not removed. This paper reports the presence of median mental sinus of dental origin in twins. One case healed following root canal therapy …

Pcna Expression In Epithelial Linings Of Odontogenic Cysts And Unicystic Ameloblastoma, Sudiono J., Rosnah Binti Zain

Prof. Dr. Rosnah Binti Zain

Proliferating cell nuclear antigen (PCNA) is a nuclear protein synthesized in the late G1 and S phase of the cell cycle. It is a useful marker for the proliferating fraction of cells in tissue specimens. The purpose of this study was to describe the expression of PCNA within epithelial linings of odontogenic cyst and to compare the proliferative activities of these lesion using PCNA labeling indices. A total of 61 cases of odontogenic cysts and unicystic ameloblastomas (18 radicular cysts, 16 dentigerous cysts, 15 odontogenic keratocysts (OKC) an 12 unicystic ameloblastomas) was studied. It was found that PCNA staining were …

Vulnerability To Depression: Reexamining State Dependence And Relative Stability, David C. Zuroff, Sidney J. Blatt, Charles A. Sanislow, Colin M. Bondi, Paul A. Pilkonis

Charles A. Sanislow, Ph.D.

Treatment-related decreases in Dysfunctional Attitudes Scale (DAS; Weissman & Beck, 1978) scores have been interpreted as evidence that dysfunctional attitudes are state-dependent concomitants of depression. Data from the National Institute of Mental Health Treatment of Depression Collaborative Research Program were used to reexamine the stability of dysfunctional attitudes. Mean scores for Perfectionism, Need for Approval, and total DAS decreased after 16 weeks of treatment. However, test-retest correlations showed that the DAS variables displayed considerable relative stability. Structural equation models demonstrated that dysfunctional attitudes after treatment were significantly predicted by initial level of dysfunctional attitudes as well as by posttreatment depression. …

Psychological And Behavioral Functioning In Adolescent Psychiatric Inpatients Who Report Histories Of Childhood Abuse, Carlos M. Grilo, Charles A. Sanislow, Dwain C. Fehon, Steve Martino, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

Objective: The purpose of this study was to examine psychological and behavioral functioning in psychiatrically hospitalized adolescents who report histories of childhood abuse. Method: Three hundred twenty-two subjects completed an assessment battery of psychometrically well-established instruments. Childhood abuse was assessed by using the childhood abuse scale of the Millon Adolescent Clinical Inventory. Childhood abuse scores of 30 or less and 70 or greater were used to create two study groups—no abuse (N=93) and high abuse (N=70), respectively. The two study groups were compared demographically and on the battery of instruments. Results: The two groups differed substantially on most measures of …

Understanding The Dental Need And Care During Pregnancy: A Review, W.C. Ngeow, W. L. Chai

Wei Cheong Ngeow

This paper reviews the oral and dental lesions that are seen during pregnancy. Trimester approach should be adopted in the management of the pregnant patients. A good dental preventive programme is essential. The significance of prescribing fluoride supplements and the use of dental radiography during pregnancy is also briefly reviewed.

Enhanced Adhesion Of Pasteurella Multocida To Cultured Turkey Peripheral Blood Monocytes, Ingrid M. Pruimbroom, Richard B. Rimler, Mark R. Ackermann

Mark R. Ackermann

Capsular hyaluronic acid (HA) mediates adhesion of serogroup A strains of Pasteurella multocida to elicited turkey air sac macrophages (TASM). In contrast, freshly isolated turkey peripheral blood monocytes (TPBM) do not bind serogroup A strains. Following culture of TPBM for 6 days in chamber slides, adhesion of the bacteria to TPBM increased gradually. Incubation in chamber slides coated with entactin-collagen IV-laminin (ECL) attachment matrix or exposure to phorbol myristate acetate (PMA) further enhanced the adhesion ofP. multocida to TPBM. Addition of HA, but not Arg-Gly-Asp peptide, to TPBM culture inhibited bacterial adherence similarly to the inhibition previously reported for TASM. …

Kennis En Houdings Van Verpleegkundiges Aangaande Die Voedingsprobleme Van Babas Met Gesplete Lip En Verhemelte, Brenda Louw, Hannelie Botha

Brenda Louw

Orbital Cellulitis As A Sole Symptom Of Odontogenic Infection, W.C. Ngeow

Wei Cheong Ngeow

A case of periapical infection resulting in unilateral maxillary sinusitis and cellulitis of the ipsilateral lower eyelid is presented. The sole symptom was right orbital swelling. The possible pathway for the spread of this type of infection predisposing factors and possible complications are reviewed. The value of radiographic examination and antibiotic therapy are also discussed.

Making Your Own Retrograde Carrier, W. L. Chai, W.C. Ngeow

Wei Cheong Ngeow

One of the problems faced by manufacturers is the difficulty in constructing a robust and reliable, angled applicator tip. This can be overcome by handmaking your own retrograde carrier. The applicator tip may be bent to about 50 degrees and, if a kink occurs while bending the tip, it can be replaced easily by a new modified needle. Because the wire used is flexible, it can adapt to the bend without a problem. Narrower carriers can also be made using a 20-G needle, perhaps more suitable for retrograde fillings of molar apices. Because the carrier is designed to be used …

Mental Health Parity: National And State Perspectives 1999, Bruce Lubotsky Levin, Ardis Hanson, Richard Coe

Ardis Hanson

Mental health parity legislation could substantially reduce the degree to which financial responsibility for the treatment of mental illness is shifted to government, especially state and local government. There is substantial evidence that both mental health and addictions treatment is effective in reducing the utilization and costs of medical services. There appears to be a lack of substantial evidence to discourage Florida from pursuing mental health and substance abuse parity legislation.

Ervilhas, Gado E Gente [Portuguese], Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.

Winter And Cardiovascular Mortality, Paulo A. Lotufo

Paulo A Lotufo

Winter time and mortality due to heart failure in Sao Paulo, Brazil during the 1930's.

Methods For Analyzing Health Care Utilization And Costs, Paula Diehr

Paula Diehr

Important questions about health care are often addressed by studying health care utilization. Utilization data have several characteristics that make them a challenge to analyze. In this paper we discuss sources of information, the statistical properties of utilization data, common analytic methods including the two-part model, and some newly available statistical methods including the generalized linear model. We also address issues of study design and new methods for dealing with censored data. Examples are presented.