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Full-Text Articles in Medicine and Health Sciences

Family History, Brca1/Brca2 Status, And Local Recurrence In Conservatively Treated Breast Cancer Patients, Elizabeth Virginia Harrold (Ratchford) Mar 2000

Family History, Brca1/Brca2 Status, And Local Recurrence In Conservatively Treated Breast Cancer Patients, Elizabeth Virginia Harrold (Ratchford)

Yale Medicine Thesis Digital Library

This study explores the relationship among young age at diagnosis, family history, BRCA1/2 status, and ipsilateral breast tumor relapse (IBTR) in conservatively treated breast cancer patients. First, age was examined as a prognostic factor for IBTR using clinical information from 984 patients in a computerized database. Second, 52 case patients who had experienced an IBTR were matched to 52 control patients from the database to determine if IBTR was associated with family history. For these 104 patients, detailed family history interviews were conducted; all data were recorded in a pedigree. A genetic counselor blind to the clinical histories then scored …


Prognostic Significance Of Histologic Regression In Thin Cutaneous Malignant Melanoma, Jason C. Sluzevich Jan 2000

Prognostic Significance Of Histologic Regression In Thin Cutaneous Malignant Melanoma, Jason C. Sluzevich

Yale Medicine Thesis Digital Library

No abstract provided.


Using An Electronic Reminder To Improve Physician Practices At Yale-New Haven Hospital, Alicia Inés Arbaje Jan 2000

Using An Electronic Reminder To Improve Physician Practices At Yale-New Haven Hospital, Alicia Inés Arbaje

Yale Medicine Thesis Digital Library

The inappropriate use of diphenhydramine (Benadryl™) can lead to iatrogenic complications, such as cognitive decline. Electronic reminders can be effective in implementing clinical guidelines, providing decision support to clinicians, and reducing medical errors. The purpose of this study was to determine the effect of an electronic reminder screen on physicians' routine use of diphenhydramine as a pretreatment prior to blood transfusions, and to assess their attitudes regarding this reminder. The researchers reviewed diphenhydramine use in adult inpatients before, immediately after, and one year after implementation of the reminder screen. A total of 752 transfusion episodes (467 patients) were reviewed, with …


The Sequential Schedule For Poliovirus Immunization: Factors Associated With Its Adoption By Primary Care Providers, Melissa Sharyn Ellis Jan 2000

The Sequential Schedule For Poliovirus Immunization: Factors Associated With Its Adoption By Primary Care Providers, Melissa Sharyn Ellis

Yale Medicine Thesis Digital Library

No abstract provided.


Severity Of Illness And Prognosis Of Liver Transplant Candidates At Yale, Arvind Venkat Jan 2000

Severity Of Illness And Prognosis Of Liver Transplant Candidates At Yale, Arvind Venkat

Yale Medicine Thesis Digital Library

The increasing number of patients with end-stage liver disease (ESLD) listed for transplantation has forced physicians to examine the disparities in waiting times (WT) for this procedure across the US. The debate has centered upon whether physicians within regions with longer WT, such as that of Yale, are listing patients prematurely compared to regions with shorter WT . Using regional variations in WT, per this argument, to analyze access to organs is therefore misleading. To determine the appropriateness of listing practices at Yale, the authors applied stratification guidelines for liver transplant candidates adopted by the United Network for Organ Sharing …