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Comparison Of Serum Levels Of Il-6, Il-8, Tnf-Α, C Reactive Protein And Heat Shock Protein 70 In Patients With Active Or Inactive Behçet’S Disease, Remzi̇ Karadağ, Cemi̇le Koca, Yüksel Totan, Ramazan Yağci, Murat Aydin, Ayşe Serap Karadağ, Celi̇le Gülfer Akbay, Hati̇ce Meral Ekşi̇oğlu, Muhammet Ramazan Yi̇ği̇toğlu
Comparison Of Serum Levels Of Il-6, Il-8, Tnf-Α, C Reactive Protein And Heat Shock Protein 70 In Patients With Active Or Inactive Behçet’S Disease, Remzi̇ Karadağ, Cemi̇le Koca, Yüksel Totan, Ramazan Yağci, Murat Aydin, Ayşe Serap Karadağ, Celi̇le Gülfer Akbay, Hati̇ce Meral Ekşi̇oğlu, Muhammet Ramazan Yi̇ği̇toğlu
Turkish Journal of Medical Sciences
The aim of this study was to elucidate serum levels of IL-6, IL-8, TNF-\alpha, CRP, and HSP 70 in patients with active or inactive Behçet's disease. Materials and methods: The study included 50 patients who met the International Study Group criteria for Behçet's disease. Of these, 26 had active disease and 24 had inactive disease. The control group was comprised of 25 age- and sex-matched healthy participants. Serum levels of IL-6, IL-8, TNF-\alpha, CRP, and HSP 70 were measured. Results: In patients with active disease, significantly higher mean serum levels of IL-6, IL-8, TNF-\alpha, and CRP were found compared to …
Does Melatonin Alleviate Cold Preservation Injury Of The Liver?, Ömer Günal, Abdurrahman Coşkun, Ari̇f Aslaner, Ümran Yildirim
Does Melatonin Alleviate Cold Preservation Injury Of The Liver?, Ömer Günal, Abdurrahman Coşkun, Ari̇f Aslaner, Ümran Yildirim
Turkish Journal of Medical Sciences
To investigate the effect of melatonin added to preservation solution on liver cold ischemia. Materials and methods: Twenty male Wistar albino rats were divided equally into groups treated with University of Wisconsin (UW) solution with and without melatonin. The LDH, AST, and ACP activities of the preservation solutions were determined in samples collected at 2, 24, 36, and 48 h. Tissue malondialdehyde and heat shock protein (HSP 70) levels were also measured and a histological examination was performed at 48 h. Results: Melatonin prevented enzyme elevation, induced heat shock protein (HSP 70), and decreased lipid peroxidation effectively in comparison to …