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Full-Text Articles in Medicine and Health Sciences
Allocentric Representation In The Human Amygdala And Ventral Visual Stream, Hallvard Røe Evensmoen, Lars M. Rimol, Anderson M. Winkler, Richard Betzel, Tor Ivar Hansen
Allocentric Representation In The Human Amygdala And Ventral Visual Stream, Hallvard Røe Evensmoen, Lars M. Rimol, Anderson M. Winkler, Richard Betzel, Tor Ivar Hansen
School of Medicine Publications and Presentations
The hippocampus and the entorhinal cortex are considered the main brain structures for allocentric representation of the external environment. Here, we show that the amygdala and the ventral visual stream are involved in allocentric representation. Thirty-one young men explored 35 virtual environments during high-resolution functional magnetic resonance imaging (fMRI) of the medial temporal lobe (MTL) and were subsequently tested on recall of the allocentric pattern of the objects in each environment-in other words, the positions of the objects relative to each other and to the outer perimeter. We find increasingly unique brain activation patterns associated with increasing allocentric accuracy in …
Associations Between Self-Reported Sleep Quality And White Matter In Community-Dwelling Older Adults: A Prospective Cohort Study, Claire E. Sexton, Enikő Zsoldos, Nicola Filippini, Ludovica Griffanti, Anderson M. Winkler, Abda Mahmood, Charlotte L. Allan, Anya Topiwala, Simon D. Kyle, Kai Spiegelhalder
Associations Between Self-Reported Sleep Quality And White Matter In Community-Dwelling Older Adults: A Prospective Cohort Study, Claire E. Sexton, Enikő Zsoldos, Nicola Filippini, Ludovica Griffanti, Anderson M. Winkler, Abda Mahmood, Charlotte L. Allan, Anya Topiwala, Simon D. Kyle, Kai Spiegelhalder
School of Medicine Publications and Presentations
Both sleep disturbances and decline in white matter microstructure are commonly observed in ageing populations, as well as in age-related psychiatric and neurological illnesses. A relationship between sleep and white matter microstructure may underlie such relationships, but few imaging studies have directly examined this hypothesis. In a study of 448 community-dwelling members of the Whitehall II Imaging Sub-Study aged between 60 and 82 years (90 female, mean age 69.2 ± 5.1 years), we used the magnetic resonance imaging technique diffusion tensor imaging to examine the relationship between self-reported sleep quality and white matter microstructure. Poor sleep quality at the time …