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Is Memantine A Safe And Effective Treatment For Alzheimer’S Disease In Patients Over The Age Of 50?, Stephanie Hoarau
Is Memantine A Safe And Effective Treatment For Alzheimer’S Disease In Patients Over The Age Of 50?, Stephanie Hoarau
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE The objective of this selective EBM review is to determine whether or not memantine is a safe and effective treatment for Alzheimer’s disease in patients over the age of 50.
STUDY DESIGN Systematic review of two randomized controlled trials published in 2006 and 2013 and one randomized controlled trial pooled analysis published in 2014.
DATA SOURCES Two randomized controlled trials and one pooled analysis were obtained using PubMed.
OUTCOMES MEASURED Efficacy of memantine as compared to control groups based on cognition, behavior, and adverse events. These were measured using Severe Impairment Battery (SIB), Neuropsychiatric Inventory (NPI), and Behavioral Pathology …
Does Herbal Medicine Have An Effect On The Cognitive Function Of Patients With Mild To Moderate Alzheimer’S Disease Over The Age Of 50?, Melissa Liebman
Does Herbal Medicine Have An Effect On The Cognitive Function Of Patients With Mild To Moderate Alzheimer’S Disease Over The Age Of 50?, Melissa Liebman
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selective evidence based medicine review is to determine whether or not “herbal medicine has an effect on the cognitive function of patients with mild to moderate Alzheimer’s disease over the age of 50”.
STUDY DESIGN: Review of three double-blind, randomized control trials published between 2003 and 2015. All studies were published in English language in peer reviewed journals.
DATA SOURCES: Three randomized control trials were found via PubMed.
OUTCOMES MEASURED: The outcomes measured include changes in Alzheimer’s symptoms based upon a neurologist, improvement of Alzheimer’s symptoms based on ADAS-cog and CDR-SOB clinical rating scale, and …