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Does Continuous Subcutaneous Hydrocortisone Infusion Therapy Improve Vitality In Adult Patients With Addison’S Disease When Compared To Oral Hydrocortisone Therapy?, Vanessa Rivas

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective systematic review is to determine whether or not continuous subcutaneous hydrocortisone infusion (CSHI) therapy improves vitality in adult patients with Addison’s disease when compared to oral hydrocortisone therapy.

STUDY DESIGN: This systematic review used three peer reviewed articles published in English. The articles were a crossover randomized control trial, a double bind placebo controlled clinical trial, and a case series published from 2007 to 2014.

DATA SOURCES: The crossover randomized control trial and the double blind, placebo randomized control trial compared adult patients with Addison’s disease vitality scores when taking oral hydrocortisone tablets to …