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The Diversity And Synaptic Connectivity Of Somatostatin-Containing Inhibitory Interneurons In The Somatosensory (Barrel) Cortex, Rachel Elaine Hostetler

Graduate Theses, Dissertations, and Problem Reports

The neocortex is the most evolutionarily advanced part of the mammalian brain and is responsible for a multitude of important tasks, such as sensory processing, movement, memory and learning and, in humans, cognition, and language. Within the neocortex, there are intricate circuits of neurons that are responsible for these tasks. These circuits are comprised of a delicate balance of excitatory and inhibitory neurons. Inhibitory interneurons have the crucial role of constraining and controlling the amount of excitation in the brain; disruptions in this balance can lead to a number of neuropsychiatric diseases and disorders. Our studies focused on the subpopulation …