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Full-Text Articles in Medicine and Health Sciences
The Effect Of Vasoconstrictors On Oxygen Consumption In Resting And Contracting Skeletal Muscle Of The Autologous Pump-Perfused Rat Hindlimb, Andrew Hoy, Peter L. Mclennan, Gregory E. Peoples
The Effect Of Vasoconstrictors On Oxygen Consumption In Resting And Contracting Skeletal Muscle Of The Autologous Pump-Perfused Rat Hindlimb, Andrew Hoy, Peter L. Mclennan, Gregory E. Peoples
Graduate School of Medicine - Papers (Archive)
No abstract provided.
Glutathione And Catalase Suppress Tgfß-Induced Cataract-Related Changes In Cultured Rat Lenses And Lens Epithelial Explants, Coral G. Chamberlain, Kylie J. Mansfield, Anna Cerra
Glutathione And Catalase Suppress Tgfß-Induced Cataract-Related Changes In Cultured Rat Lenses And Lens Epithelial Explants, Coral G. Chamberlain, Kylie J. Mansfield, Anna Cerra
Graduate School of Medicine - Papers (Archive)
Purpose: The damaging effects of oxidative stress and transforming growth factor-β (TGFβ)-induced transdifferentiation of lens epithelial cells have both been implicated independently in the etiology of cataract. The aim of this study was to investigate whether the presence of antioxidant systems in the lens influences the ability of lens epithelial cells to respond to TGFβ.
Methods: Whole lenses from young rats were cultured with or without TGFβ in the presence or absence of reduced glutathione (GSH). Lens epithelial explants from weanling rats were used to investigate the effects of GSH and catalase on TGFβ-induced cataract-related changes. Lenses were monitored for …