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Full-Text Articles in Medicine and Health Sciences
Decipher Mechanisms By Which Nuclear Respiratory Factor One (Nrf1) Coordinates Changes In The Transcriptional And Chromatin Landscape Affecting Development And Progression Of Invasive Breast Cancer, Jairo Ramos
FIU Electronic Theses and Dissertations
Despite tremendous progress in the understanding of breast cancer (BC), gaps remain in our knowledge of the molecular basis underlying the aggressiveness of BC and BC disparities. Nuclear respiratory factor 1 (NRF1) is a transcription factor (TF) known to control breast cancer cell cycle progression. DNA response elements bound by NRF1 positively correlate with the progression of malignant breast cancer. Mechanistic aspects by which NRF1 contributes to susceptibility to different breast tumor subtypes are still not fully understood. Therefore, the primary objective of this dissertation was to decipher mechanisms by which NRF1 coordinates changes in the transcriptional and chromatin landscape …
Impact Of A Nutrition And Yoga Intervention In Breast Cancer Suvivors' Quality Of Life, Tammy C. Fogarty
Impact Of A Nutrition And Yoga Intervention In Breast Cancer Suvivors' Quality Of Life, Tammy C. Fogarty
FIU Electronic Theses and Dissertations
The aim of the present study was to determine if a nutrition and yoga intervention will improve quality of life (QoL) in breast cancer survivors (BCS). Using the Transactional Model of Stress and Coping as a guide to lead the intervention, the intervention assessed potential barriers, self-efficacy, diet quality, and physical activity as it relates to quality of life. Twenty-seven women were enrolled in the study and randomly assigned to the control or intervention group. The intervention consisted of 6-weeks of yoga classes and 6-weeks of online nutrition education. The control group received a nutrition consultation and nutrition guidelines from …